AI & Machine Learning Venture Capital Firms

Browse 1,256 venture capital firms investing in AI & Machine Learning startups. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

.406 Ventures

Early-stage firm investing in digital health and data/security infrastructure, including healthcare IT and enterprise SaaS.

  • Healthcare
  • Other
  • Security
  • Seed, Series A
  • $750K – $6.0M
  • Boston, MA
  • 97 portfolio companies

01 Advisors

Operator-led enterprise fund investing in technical B2B software, including security and infrastructure products. Helpful for founders needing enterprise GTM and scaling support.

  • Enterprise
  • Security
  • Developer Tools
  • Seed, Series A
  • $500K – $3.0M
  • San Francisco, CA
  • 13 portfolio companies

1Sharpe Ventures

Early-stage fund investing in frontier/AI and enterprise software, often at pre-seed with conviction checks.

  • AI / ML
  • SaaS
  • Developer Tools
  • Pre-Seed, Seed
  • $250K – $1.5M
  • San Francisco, CA
  • 23 portfolio companies

2048 Ventures

Pre-seed/seed fund focused on being an early check for software companies across sectors.

  • Other
  • SaaS
  • Enterprise
  • Pre-Seed, Seed
  • $250K – $1.0M
  • Alexandria, VA
  • 26 portfolio companies

217 Capital

Invests in early-stage AI-driven startups focused on transforming traditional industries like real estate, construction, and logistics.

  • Other
  • AI / ML
  • Pre-Seed, Seed
  • $500K – $2.0M
  • Boulder, CO
  • 1 portfolio company

2XN Ventures

2XN Ventures backs disruptive SaaS startups leveraging AI for business efficiency and workflow transformation.

  • SaaS
  • AI / ML
  • Other
  • Pre-Seed, Seed
  • $250K – $1.0M
  • New York, NY
  • 33 portfolio companies

305 Ventures

305 Ventures invests in transformative technologies addressing climate change and supporting sustainable development across the African continent.

  • Other
  • AI / ML
  • Fintech
  • Pre-Seed, Seed
  • $100K – $1.0M
  • Cape Town, South Africa
  • 11 portfolio companies

305 Ventures

305 Ventures invests in transformative technologies addressing climate change and supporting sustainable development across the African continent.

  • Other
  • AI / ML
  • Fintech
  • Pre-Seed, Seed
  • $100K – $1.0M
  • Cape Town, South Africa
  • 22 portfolio companies

360 Ventures

Backs cutting-edge companies transforming the workplace using AI and SaaS solutions targeted at HR and training.

  • Other
  • SaaS
  • AI / ML
  • Seed
  • $500K – $3.5M
  • Boston, MA
  • 200 portfolio companies

404 Founders

404 Founders is a microfund specializing in European and African B2B SaaS and enterprise technology innovations.

  • SaaS
  • Other
  • Enterprise
  • Pre-Seed
  • $200K – $1.0M
  • Berlin, Germany
  • 6 portfolio companies

511 Ventures

511 Ventures focuses on AI-enabled enterprise infrastructure and tools aimed at safety, stability, and optimization within high-consequence B2B verticals.

  • Other
  • Deep Tech
  • SaaS
  • Seed, Series A
  • $250K – $2.5M
  • Boston, MA
  • 1 portfolio company

A16z Crypto Seed Fund

Andreessen Horowitz Crypto Seed Fund focuses solely on decentralized, blockchain, and crypto projects that enable efficient economic systems.

  • Other
  • AI / ML
  • Developer Tools
  • Pre-Seed, Seed
  • $500K – $3.0M
  • Menlo Park, CA
  • 103 portfolio companies

ACME Capital

ACME Capital supports early-stage companies modernizing infrastructure, enterprise technologies, and industrial workflows.

  • SaaS
  • AI / ML
  • Other
  • Seed, Series A
  • $1.0M – $3.0M
  • San Francisco, CA
  • 8 portfolio companies

AEC Innovate Fund

Focused on investing in groundbreaking technologies within the AEC industry that leverage AI to improve efficiency and reduce costs.

  • Real Estate
  • Other
  • AI / ML
  • pre_seed
  • $1.0M – $3.0M
  • Austin, TX
  • 2 portfolio companies

AFRICAGrow Ventures

AfricaGrow Ventures invests in technology-powered African startups that enhance financial inclusion and agricultural productivity.

  • Other
  • Fintech
  • Consumer
  • Pre-Seed, Seed
  • $200K – $750K
  • Lagos, Nigeria
  • 36 portfolio companies

AI Alliance Fund

Backing AI-driven technologies across industries, with a key emphasis on enterprise and B2B intelligence solutions.

  • AI / ML
  • SaaS
  • seed+, Series A
  • $1.0M – $5.0M
  • San Francisco, CA
  • 37 portfolio companies

AI Amplify Fund

AI Amplify Fund is dedicated to supporting AI-driven productivity software that enhances connectivity and collaboration.

  • Other
  • AI / ML
  • SaaS
  • Pre-Seed, Seed
  • $300K – $1.5M
  • Boston, MA
  • 36 portfolio companies

AI Angel Fund

AI Angel Fund invests in early-stage companies leveraging AI for business and government applications, with a particular focus on ethical AI and SaaS platforms.

  • AI / ML
  • SaaS
  • Other
  • Pre-Seed, Seed
  • $50K – $250K
  • Austin, TX
  • 53 portfolio companies

AI Defense Network

Invests in startups using AI to spearhead innovations in cybersecurity, enhancing threat detection and response capabilities.

  • Security
  • Other
  • AI / ML
  • Seed, Series A
  • $500K – $3.0M
  • Chicago, IL
  • 16 portfolio companies

AI Diagnostics Fund

Investing exclusively in AI-driven diagnostics solutions for healthcare.

  • AI / ML
  • Other
  • Healthcare
  • Pre-Seed
  • $500K – $1.0M
  • San Francisco, CA
  • 4 portfolio companies

AI Evolution Fund

Invests in AI infrastructure that supports enterprise-level implementations, with a focus on scalable and secure platforms.

  • AI / ML
  • Enterprise
  • Seed
  • $2.0M – $4.0M
  • Boston, MA
  • 1 portfolio company

AI Fortify Fund

Dedicated to early-stage AI applications enhancing competitive intelligence and strategic decision-making.

  • Other
  • AI / ML
  • Developer Tools
  • Pre-Seed
  • $200K – $500K
  • Austin, TX
  • 3 portfolio companies

AI Frontier Ventures

Focused on innovative AI/ML B2B SaaS solutions that enhance decision-making and automate business processes.

  • AI / ML
  • SaaS
  • Enterprise
  • Pre-Seed
  • $50K – $250K
  • San Francisco, CA
  • 19 portfolio companies

AI Fund

AI Fund focuses on investing in AI-first startups applying machine learning to solve industry-specific challenges.

  • AI / ML
  • SaaS
  • Pre-Seed, Seed
  • $500K – $3.0M
  • Palo Alto, CA
  • 8 portfolio companies

Showing 1–24 of 1256 firms — page 1 of 53.

Frequently Asked Questions

Which VC firms invest in AI & Machine Learning?
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