Series A AI & Machine Learning Venture Capital Firms

Browse 575 venture capital firms that invest in AI & Machine Learning startups at the Series A stage. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified Series A AI & Machine Learning VC firms

Terrapact Capital

Funding scalable technologies in sustainable development and carbon credit platforms, with strong focus on North American startups.

  • Climate / Energy
  • Other
  • SaaS
  • Seed, Series A
  • $1.0M – $5.0M
  • Toronto, Canada
  • 2 portfolio companies

.406 Ventures

Early-stage firm investing in digital health and data/security infrastructure, including healthcare IT and enterprise SaaS.

  • Healthcare
  • Other
  • Security
  • Seed, Series A
  • $750K – $6.0M
  • Boston, MA
  • 88 portfolio companies

01 Advisors

Operator-led enterprise fund investing in technical B2B software, including security and infrastructure products. Helpful for founders needing enterprise GTM and scaling support.

  • Enterprise
  • Security
  • Developer Tools
  • Seed, Series A
  • $500K – $3.0M
  • San Francisco, CA
  • 8 portfolio companies

20VC

Media-venture hybrid investing at the intersection of venture, software, and internet distribution. The firm backs early-stage companies across consumer and B2B software with strong product and narrat...

  • Other
  • Consumer
  • Enterprise
  • Pre-Seed, Seed, Series A
  • $100K – $3.0M
  • London, England
  • 11 portfolio companies

359 Capital

A venture investor active in software and data-driven businesses. SportsVisio’s inclusion in its portfolio indicates it will consider AI sports analytics and video automation deals.

  • AI / ML
  • SaaS
  • Other
  • Seed, Series A
  • Atlanta, Georgia

511 Ventures

511 Ventures focuses on AI-enabled enterprise infrastructure and tools aimed at safety, stability, and optimization within high-consequence B2B verticals.

  • Other
  • Deep Tech
  • SaaS
  • Seed, Series A
  • $250K – $2.5M
  • Boston, MA
  • 1 portfolio company

ACME Capital

ACME backs deep-tech founders with technical ambition and decisive execution, investing in frontier technologies before they become mainstream. Its current portfolio includes areas such as AI, autonom...

  • SaaS
  • AI / ML
  • Other
  • Seed, Series A
  • $1.0M – $3.0M
  • San Francisco, United States
  • 8 portfolio companies

ACP Healthtech

Capital-efficient healthcare investing at regulatory inflection points, targeting B2B healthtech, AI diagnostics, smart medtech, and B2B software with global reach across the EU, US, and Middle East.

  • Healthcare
  • SaaS
  • AI / ML
  • Series A, Growth
  • Germany
  • 6 portfolio companies

AENU

Impact-first climate investor backing companies that decarbonize industries and infrastructure. While not a legaltech specialist, it is relevant for carbon-compliance automation and sustainability rep...

  • Climate / Energy
  • AI / ML
  • Developer Tools
  • Seed, Series A
  • Berlin, Germany
  • 43 portfolio companies

AI Alliance Fund

Backing AI-driven technologies across industries, with a key emphasis on enterprise and B2B intelligence solutions.

  • AI / ML
  • SaaS
  • seed+, Series A
  • $1.0M – $5.0M
  • San Francisco, CA
  • 37 portfolio companies

AI Defense Network

Invests in seed and Series A startups using AI, cybersecurity, national/public safety or dual-use defense technologies, especially those innovating in security, AI/ML and threat detection or response.

  • Security
  • Other
  • AI / ML
  • Seed, Series A
  • $500K – $3.0M
  • Chicago, United States
  • 16 portfolio companies

AI Fintech Partners

Dedicated to advancing AI-centric fintech startups that improve financial workflows, debt solutions, and operational efficiencies.

  • AI / ML
  • Fintech
  • Other
  • Seed, Series A
  • $1.0M – $7.0M
  • Atlanta, GA
  • 2 portfolio companies

AI First Capital

AI First Capital specializes in early-stage companies using artificial intelligence to solve industry-specific problems, focusing on verticalized AI applications.

  • AI / ML
  • SaaS
  • Other
  • Pre-Seed, Seed, Series A
  • $500K – $3.0M
  • Palo Alto, CA
  • 8 portfolio companies

AI Government Fund

Focused on government utilization of AI to improve public services and operations within government agencies.

  • AI / ML
  • Other
  • Series A
  • $1.5M – $12.0M
  • Chicago, IL

AI Inspection Labs

Specializes in AI-driven industrial inspection technologies that enhance operational safety and efficiency.

  • Other
  • AI / ML
  • Seed, Series A
  • $300K – $3.5M
  • Boston, MA
  • 1 portfolio company

AI Media Innovators

Supports innovative AI technologies in the media sector to drive narrative creation and consumer engagement through predictive analytics.

  • AI / ML
  • Other
  • Series A
  • Up to $20.0M

AI Native Ventures

Invests in AI-native platforms with infrastructural applications for enterprise software systems and integrations.

  • AI / ML
  • SaaS
  • Seed, Series A
  • $500K – $3.0M
  • New York, NY
  • 1 portfolio company

AI Propulsion Fund

Focuses exclusively on companies propelling AI technologies for use cases in marketing and enterprise visibility solutions.

  • SaaS
  • Other
  • AI / ML
  • Seed, Series A
  • $1.0M – $3.0M
  • Toronto, Canada
  • 1 portfolio company

AI Strategy Fund

Targets AI-driven SaaS solutions with data analytics components that transform business operations.

  • AI / ML
  • Developer Tools
  • SaaS
  • Series A
  • $5.0M – $10.0M
  • Austin, TX

AI Ventures Foundry

AI Ventures Foundry is a micro-fund investing exclusively in AI-driven enterprises with a strong B2B SaaS model, focusing on early-stage investments.

  • AI / ML
  • SaaS
  • Enterprise
  • Series A
  • $2.5M – $4.0M
  • San Francisco, CA
  • 16 portfolio companies

AI and Industry Fund

Focuses on AI investments that drive efficiencies in industrial sectors, including logistics.

  • AI / ML
  • Other
  • Seed, Series A
  • $500K – $3.0M
  • Boston, MA

AI in Manufacturing Fund

Invests in early-stage companies using AI to transform manufacturing processes and capabilities.

  • AI / ML
  • Other
  • SaaS
  • Pre-Seed, Seed, Series A
  • $300K – $3.0M
  • Tokyo, Japan
  • 2 portfolio companies

AMD Ventures

AMD Ventures invests across the AI ecosystem from hardware to software and is strategically relevant to chip design and verification infrastructure. It can be valuable when the company aligns with nex...

  • Other
  • AI / ML
  • Seed, Series A, Growth
  • Santa Clara, California

AMP Robotics Capital

Specialized in AI/ML startups with productivity-focused applications, especially those targeting operational efficiency in commerce and logistics sectors.

  • AI / ML
  • Other
  • Seed, Series A
  • $500K – $3.0M
  • New York, NY
  • 3 portfolio companies

Showing 1–24 of 575 firms — page 1 of 24.

Frequently Asked Questions

How many VCs invest in AI & Machine Learning at the Series A stage?
Investor Match tracks 575 verified venture capital firms that back AI & Machine Learning startups at the Series A stage.
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Upload your pitch deck and Investor Match will score every Series A AI & Machine Learning investor by fit, so you can focus outreach on the best matches.
Are these Series A AI & Machine Learning VC firms verified?
Yes. Every firm listed is verified for an active website and investing activity before it appears in the directory.

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