Series A AI & Machine Learning Venture Capital Firms

Specializes in climate-resilient tech and sustainable infrastructure for industrial and global applications.

• Other
• Developer Tools
• AI / ML

• Seed, Series A
• $1.0M – $5.0M
• Singapore
• 2 portfolio companies

Invests in technically differentiated companies across AI and healthcare. A proprietary claims-event dataset and autonomous operating stack are well within its thesis area.

• AI / ML
• Healthcare
• SaaS

• Series A
• San Francisco, California
• 50 portfolio companies

French specialist investor active in defense and adjacent industrial technologies. The firm participates in defense-tech financing and is relevant for hardware requiring industrialization.

• Other
• Security
• AI / ML

• Seed, Series A
• Paris, France
• 6 portfolio companies

Focused exclusively on transformative healthcare technology solutions that address hospital challenges and improve care delivery via AI and SaaS models.

• Other
• Healthcare
• SaaS

• Seed+, Series A
• $3.0M – $10.0M
• Boston, MA
• 2 portfolio companies

Growth-oriented software investor with a history in enterprise software and AI-enabled automation. Particularly relevant when the product has strong SaaS retention and operational workflow value.

• Enterprise
• AI / ML
• SaaS

• Seed, Series A
• New York, New York
• 2 portfolio companies

Addition Ventures backs enterprise and vertical software with strong operational value. It is relevant for businesses that combine software workflow control with a narrow operational customer segment.

• Enterprise
• SaaS
• Other

• Seed, Series A
• $500K – $3.0M
• Cambridge, Massachusetts
• 16 portfolio companies

Investor in AI Diagnostics, suggesting an interest in medtech and healthcare solutions serving emerging markets. The regional orientation may align with India and other frontier markets.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed, Series A
• 13 portfolio companies

Specialist investor in African agribusinesses providing patient capital and sector expertise. Invests in agriculture value chains and operational businesses that strengthen food systems across Africa.

• Food / AgTech
• Other
• Consumer

• Seed, Series A
• $1.1M – $10.0M
• London, England
• 16 portfolio companies

Fostering early-stage innovations in agricultural technology through strategic funding of startups poised to optimize food supply chains.

• Food / AgTech
• Fintech
• AI / ML

• Seed, Series A
• $500K – $3.0M
• London, UK
• 1 portfolio company

AI-first solo GP backing technical founders building software, developer tools, and AI infrastructure. The fund is especially strong for early technical products with research depth and infrastructure...

• AI / ML
• Developer Tools
• Enterprise

• Pre-Seed, Seed, Series A
• $500K – $25.0M
• London, England
• 27 portfolio companies

Airtree backs ambitious Australian and New Zealand technology founders, investing from pre-seed and seed through growth. Its current thesis emphasizes exceptional founders pursuing globally scalable o...

• AI / ML
• Other
• Marketplace

• Pre-Seed, Seed, Series A
• $500K – $5.0M
• Sydney, Australia
• 49 portfolio companies

They invest in early-stage AI-native companies (Pre-seed to Series A) where AI is a core component of the product, across sectors like infrastructure, enterprise software, healthcare/life sciences, an...

• Other
• SaaS
• AI / ML

• Seed, Series A
• $1.0M – $5.0M
• Newark, California, United States
• 31 portfolio companies

Akkadian Ventures is a venture secondary investment firm that provides liquidity to founders, employees, and early investors, and invests across primary and secondary private-technology transactions, ...

• Enterprise
• Other
• SaaS

• Seed, Series A
• $250K – $10.0M
• San Francisco, California, United States
• 47 portfolio companies

Focuses on ventures rethinking the future of commerce and retail sustainability, including furniture, home goods, and fashion.

• Other
• Climate / Energy
• AI / ML

• Seed, Series A
• $500K – $3.0M
• Chicago, IL
• 16 portfolio companies

AlignThesis backs startups proving measurable productivity gains in enterprise environments, including vertical SaaS targeting HR and people operations.

• Other
• SaaS
• Enterprise

• Seed, Series A
• $700K – $5.0M
• Chicago, IL
• 2 portfolio companies

Pre-seed, Seed, Series A tech startups across USA & Canada.

• SaaS
• Fintech
• Other

• Pre-Seed, Seed, Series A
• $100K – $350K
• 87 portfolio companies

Invests in software-driven healthcare transformation, especially AI-enabled tools that improve operating leverage in care delivery. Good fit for back-office automation and practice management software...

• Healthcare
• AI / ML
• Other

• Seed, Series A
• US
• 33 portfolio companies

Invests at the intersection of enterprise SaaS and AI/ML innovation, targeting scalable B2B solutions.

• SaaS
• AI / ML

• seed+, Series A
• $1.5M – $3.0M
• New York, NY
• 12 portfolio companies

Focuses on early-stage investments in AI-backed solutions transforming B2B marketing, sales, and customer engagement strategies.

• Other
• AI / ML
• SaaS

• Seed, Series A
• $300K – $1.5M
• Chicago, IL
• 2 portfolio companies

Focuses on B2B SaaS startups leveraging data and AI-driven automation.

• SaaS
• Marketplace
• AI / ML

• Seed, Series A
• $300K – $2.0M
• New York, NY
• 2 portfolio companies

Multi-fund platform investing in venture-backed startups at seed and beyond, often co-investing in priced seed rounds.

• Other
• Healthcare
• AI / ML

• Seed, Series A
• $250K – $3.0M
• Manchester, NH
• 34 portfolio companies

They invest from seed to growth in deep tech—specifically in Intelligence (AI, advanced computing, quantum), Human (health, medicine, wellness), and Planet (sustainability, novel materials, space)—bac...

• AI / ML
• Healthcare
• SaaS

• Seed, Series A
• $1.0M – $5.0M
• London / Cambridge / Oxford, United Kingdom
• 46 portfolio companies

Corporate venture arm focused on voice innovation, smart devices, AI, and entertainment. While broader than a niche fund, it is highly relevant for products that make voice a core interface layer acro...

• Other
• AI / ML
• Consumer

• Seed, Series A, Series B
• Seattle, Washington
• 5 portfolio companies

Seed and early-stage venture firm focused on AI and data companies. Could be interested in an AI-native operating system if the product demonstrates strong data capture and decision automation.

• AI / ML
• Developer Tools
• Enterprise

• Seed, Series A
• $250K – $2.0M
• Palo Alto, CA
• 45 portfolio companies