.406 Ventures
.406 Ventures is a Seed, Series A venture capital firm based in Boston, MA investing in Healthcare, Other, Security. The firm typically writes $750K–$6.0M checks and has 97 portfolio companies in our records.
- Check size
- $750K–$6.0M
- Portfolio
- 97 companies on record
- Partners
- 11 listed
- Stage
- Seed, Series A
- Sectors
- Healthcare, Other, Security, Developer Tools, AI / ML, SaaS, Enterprise
- HQ
- Boston, MA
- AUM
- Not in our records
Last verified: 2026-04-12
Seed, Series A
$750K – $6.0M
97+ companies
11 partners
Investment Thesis
Early-stage firm investing in digital health and data/security infrastructure, including healthcare IT and enterprise SaaS.
How .406 Ventures invests
.406 Ventures is a vc firm based in Boston, MA. The firm invests at the Seed, Series A stages, with a focus on Healthcare, Other, Security, Developer Tools, AI / ML.
.406 Ventures typically writes checks of $750K–$6.0M per investment.
.406 Ventures has backed 97 companies in our records, including Iora Health, Health Verity, Corvus.
Partners & Team
Maria Palma
General Partner
Trip Hofer
Venture Partner
Industry Focus
Invests In
Portfolio Companies (97)
Other
Iora Health
Health Verity
Corvus
AbleTo
Bluebird Kids Health
Multi-disciplinary pediatric health platform.
Bobsled
Data sharing platform for providers, SaaS companies, and others.
FamilyWell
Mindgard
NaceAI
OncoveryCare
Cancer survivorship care platform.
- •Raising at Seed, Series A? You're squarely in their sweet spot.
- •Lead with your fit in Healthcare, Other, Security — the sectors they actively back.
- •Size your ask to their typical $750K – $6.0M check.
- •warm intro preferred
- •Address your outreach to a specific partner, such as Maria Cirino, Managing Partner.
- •A warm introduction beats a cold email. Get matched and request an intro.
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