Venture Capital Firms in San Francisco

Browse 972 venture capital firms headquartered in San Francisco. Median check across the 972 firms that disclose a range is $500K–$2.5M; most active at Seed, Pre-Seed, Series A; concentrated in SaaS, AI / ML, Enterprise. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

01 Advisors

Operator-led enterprise fund investing in technical B2B software, including security and infrastructure products. Helpful for founders needing enterprise GTM and scaling support.

  • Enterprise
  • Security
  • Developer Tools
  • Seed, Series A
  • $500K – $3.0M
  • San Francisco, CA
  • 13 portfolio companies

0xVentures

Investing in early-stage Blockchain startups innovating in DeFi, tokenization, and core infrastructure.

  • Other
  • Pre-Seed, Seed
  • $500K – $2.5M
  • San Francisco, CA
  • 1 portfolio company

1M1B Ventures

1M1B Ventures invests in startups solving societal challenges using AI for Governance and impact-driven technology solutions in underserved regions.

  • Other
  • seed+
  • $250K – $5.0M
  • San Francisco, CA & Bengaluru, India
  • 2 portfolio companies

1Sharpe Ventures

Early-stage fund investing in frontier/AI and enterprise software, often at pre-seed with conviction checks.

  • AI / ML
  • SaaS
  • Developer Tools
  • Pre-Seed, Seed
  • $250K – $1.5M
  • San Francisco, CA
  • 23 portfolio companies

1confirmation

Early-stage investment fund focused exclusively on blockchain, Web3, and crypto startups reshaping financial systems.

  • Other
  • Pre-Seed, Seed
  • $250K – $1.5M
  • San Francisco, CA
  • 2 portfolio companies

3rd Rail Capital

Focuses on fintech infrastructure with an emphasis on blockchain-based systems for lending and payments.

  • Fintech
  • Other
  • Pre-Seed
  • $50K – $300K
  • San Francisco, CA
  • 1 portfolio company

50 Years (impact; education possible)

Invests in companies solving major world problems; education and economic opportunity can fit where outcomes are measurable.

  • Other
  • EdTech
  • Healthcare
  • Seed
  • $250K – $2.0M
  • San Francisco, CA

50 Years VC

Focuses on startups building deep tech solutions to tackle the world's biggest problems, including sustainability, climate change, and urban innovation.

  • Other
  • Deep Tech
  • Seed, seed+
  • $1.0M – $4.0M
  • San Francisco, CA
  • 4 portfolio companies

500 Global

Global early-stage investor and accelerator platform investing at pre-seed/seed across software categories.

  • Other
  • SaaS
  • Enterprise
  • Pre-Seed, Seed
  • $100K – $2.0M
  • San Francisco, CA
  • 5 portfolio companies

5050 VC

Early-stage fund backing diverse founding teams across software and general technology.

  • Other
  • SaaS
  • Enterprise
  • Pre-Seed, Seed
  • $50K – $500K
  • San Francisco, CA
  • 37 portfolio companies

8VC

Building companies that transform analog industries through software.

  • Enterprise
  • Healthcare
  • Real Estate
  • Seed, Series A
  • $500K – $20.0M
  • US-SF
  • 23 portfolio companies

ACME Capital

ACME Capital supports early-stage companies modernizing infrastructure, enterprise technologies, and industrial workflows.

  • SaaS
  • AI / ML
  • Other
  • Seed, Series A
  • $1.0M – $3.0M
  • San Francisco, CA
  • 8 portfolio companies

Abstract Ventures

Early-stage fund investing in ambitious founders across consumer and enterprise software.

  • Other
  • Pre-Seed, Seed
  • $250K – $1.0M
  • San Francisco, CA
  • 5 portfolio companies

Accel

From the earliest stages through all phases of growth, we help founders become the best version of themselves.

  • SaaS
  • Consumer
  • Developer Tools
  • Seed, Series A
  • $1.0M – $20.0M
  • US-SF
  • 3 portfolio companies

Acceleprise Ventures

Primarily invests in early-stage B2B SaaS companies with an accelerator model.

  • SaaS
  • Pre-Seed, Seed
  • $500K – $1.5M
  • San Francisco, CA
  • 68 portfolio companies

Accelerator Ventures

Invests very early in technology companies, often at pre-seed/seed, with a long-running focus on helping founders get to product-market fit.

  • SaaS
  • Other
  • Marketplace
  • Pre-Seed, Seed
  • $250K – $1.5M
  • San Francisco, CA
  • 28 portfolio companies

Accessibility Ventures

Accessibility Ventures focuses solely on investing in assistive technology and startups improving the lives of people with disabilities globally.

  • Other
  • EdTech
  • Healthcare
  • Pre-Seed, Seed
  • $500K – $3.0M
  • San Francisco, CA
  • 18 portfolio companies

Acrew Capital

Enterprise software investor; not HR-specific but strong at early enterprise go-to-market and AI/data products.

  • SaaS
  • Other
  • AI / ML
  • Pre-Seed, Seed
  • $1.0M – $3.0M
  • San Francisco, CA
  • 11 portfolio companies

Actual Ventures

Focuses on early-stage consumer-facing companies shaping how people engage with media and culture.

  • Other
  • Consumer
  • Pre-Seed, Seed
  • $500K – $2.0M
  • San Francisco, CA
  • 1 portfolio company

Acuity Ventures

Acuity Ventures focuses exclusively on early-stage startups building compliance, audit, and accounting innovation, particularly AI-driven tools for regulated industries.

  • Other
  • SaaS
  • Seed
  • $750K – $5.0M
  • San Francisco, CA
  • 2 portfolio companies

Acústica Ventures

Focused on companies using acoustic technologies to innovate within biotech and medical device sectors.

  • Healthcare
  • Other
  • Pre-Seed
  • $75K – $250K
  • San Francisco, CA
  • 1 portfolio company

AdCapsule Ventures

AdCapsule Ventures focuses on early-stage investments in AdTech and Programmatic Advertising startups, particularly those advancing innovations in DOOH and measurement solutions.

  • Other
  • Pre-Seed, Seed
  • $250K – $1.5M
  • San Francisco, CA
  • 2 portfolio companies

a]ventures

Early-stage fund for technical founders building developer infrastructure.

  • Developer Tools
  • AI / ML
  • Pre-Seed, Seed
  • $100K – $1.0M
  • US-SF
  • 10 portfolio companies

a_capital

a_capital invests in foundational technologies underpinning the evolution of AI and computing infrastructure with enterprise utility.

  • AI / ML
  • Enterprise
  • Developer Tools
  • Seed, Early Growth, Deployment-ready Architecture
  • $1.0M – $3.0M
  • San Francisco, CA
  • 9 portfolio companies

Showing 1–24 of 972 firms — page 1 of 41.

Frequently Asked Questions

How many VC firms are based in San Francisco?
Investor Match tracks 972 verified venture capital firms headquartered in San Francisco.
What is a typical check size for VC firms in San Francisco?
Across the 972 firms in San Francisco that disclose a range, the median check runs $500K–$2.5M. Individual firms vary widely — check each profile for its own range.
What stages do San Francisco VC firms invest at?
The most common stage focuses among San Francisco firms we track are Seed (774), Pre-Seed (611), Series A (159). Firms often invest across more than one stage.
Which sectors do San Francisco investors back most?
The sectors most represented among San Francisco firms we track are SaaS (445), AI / ML (305), Enterprise (250).
How do I get introduced to investors in San Francisco?
Upload your pitch deck to Investor Match and we'll match you with investors in San Francisco that fit your startup, then help you reach out.
Do VC firms in San Francisco only invest locally?
No. Most venture firms headquartered in San Francisco invest across regions, though many favor startups they can meet in person. Check each firm's thesis for geographic focus.

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