Venture Capital Firms in Chicago

Browse 717 venture capital firms headquartered in Chicago. Median check across the 708 firms that disclose a range is $500K–$2.5M; most active at Seed, Pre-Seed, Series A; concentrated in SaaS, AI / ML, Enterprise. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified Chicago VC firms

Decision Impact Fund

Aims to empower technologies transforming decision-making through innovative AI applications.

  • Other
  • AI / ML
  • Pre-Seed
  • $75K – $200K
  • Chicago, IL
  • 1 portfolio company

Delta Seed Partners

Focused on seed-stage SaaS ventures addressing B2B operational inefficiencies.

  • SaaS
  • Seed
  • $500K – $3.0M
  • Chicago, IL
  • 1 portfolio company

DentalTech Ventures

Invests exclusively in dental innovations, including technology, diagnostics, and consumer-facing products designed for dental channels.

  • Other
  • Seed, Series A
  • $250K – $3.0M
  • Chicago, IL
  • 1 portfolio company

DestinationNext Ventures

Invests in innovative travel and tourism solutions that help destinations manage and improve visitor experiences.

  • Other
  • Pre-Seed, Seed
  • $250K – $1.0M
  • Chicago, IL
  • 1 portfolio company

DevOps Innovators Fund

Targets world-class DevOps and infrastructure startups that enable efficient AI operations at scale, prioritizing real-time analytics and automation.

  • Developer Tools
  • AI / ML
  • Seed
  • $1.3M – $4.0M
  • Chicago, IL
  • 1 portfolio company

DiagNovate Ventures

Invests in groundbreaking companies innovating in diagnostics through AI and bioinformatics.

  • Other
  • AI / ML
  • Seed
  • $300K – $750K
  • Chicago, IL

Diagnostic Innovation Fund

Specializes in investing in early-stage companies that are pioneering new diagnostic technologies.

  • Other
  • SaaS
  • Seed
  • $250K – $1.0M
  • Chicago, IL

Digest Ventures

Digest Ventures focuses on cutting-edge solutions improving operations and efficiency for foodservice and hospitality businesses, particularly tech-driven SaaS platforms for independent operators.

  • Other
  • SaaS
  • Food / AgTech
  • Pre-Seed, Seed
  • $500K – $3.0M
  • Chicago, IL
  • 2 portfolio companies

Digital Compliance Fund

Focused on compliance, regulatory innovations, and enterprise SaaS solutions that enhance data security and oversight.

  • Other
  • Enterprise
  • SaaS
  • Seed, Series A
  • $1.0M – $5.0M
  • Chicago, IL
  • 2 portfolio companies

Digital Foresight Seed Fund

Invests in technical founders building category-defining AI/ML and SaaS platforms for underserved markets.

  • AI / ML
  • SaaS
  • Other
  • Pre-Seed, Seed
  • $50K – $1.0M
  • Chicago, IL
  • 2 portfolio companies

Digital Genre Lab

Supports development of genre-specific digital content with a preference for horror and thriller categories that show strong online distribution potential.

  • Other
  • development
  • $500K – $2.0M
  • Chicago, IL
  • 1 portfolio company

Digital Health Emerging Ventures

Invests in early-stage digital health and healthcare SaaS platforms focusing on innovative solutions for practitioners.

  • Healthcare
  • SaaS
  • Pre-Seed
  • $300K – $1.0M
  • Chicago, IL
  • 10 portfolio companies

Digital Health Seed Fund

Partnering with digital health startups that streamline operations in mid-market healthcare facilities.

  • Healthcare
  • SaaS
  • Seed
  • $500K – $1.5M
  • Chicago, IL
  • 1 portfolio company

Digital Retail Partners

Focused on disrupting traditional retail through innovative E-commerce solutions, particularly platforms enhancing B2B digital transactions.

  • Other
  • Seed, Series A
  • $500K – $2.5M
  • Chicago, IL

Diverse Journey Ventures

Invests in culturally rich and creator-led businesses that transcend borders and foster community engagement.

  • Other
  • Pre-Seed
  • $500K – $3.0M
  • Chicago, IL
  • 1 portfolio company

DocuAI Fund

Focuses on companies delivering AI-driven solutions to improve healthcare documentation and operations.

  • Other
  • Healthcare
  • $1.5M pre-seed, Early-Stage
  • $200K – $2.0M
  • Chicago, IL
  • 1 portfolio company

Dogma Ventures

Dogma Ventures specializes in funding premium pet food and products tailored to the modern pet owner's lifestyle.

  • Other
  • Consumer
  • AI / ML
  • Pre-Seed, Seed
  • $300K – $2.5M
  • Chicago, IL
  • 27 portfolio companies

Domain Ventures

Invests in PropTech and FinTech startups that demonstrate the potential to transform property and finance industries.

  • Real Estate
  • Fintech
  • Seed
  • $1.0M – $3.0M
  • Chicago, IL
  • 1 portfolio company

DrivenVC

Invests in early-stage enterprise SaaS products empowering teams to collaborate effectively using AI and advanced analytics.

  • SaaS
  • AI / ML
  • Other
  • Pre-Seed, Seed
  • $250K – $750K
  • Chicago, IL
  • 2 portfolio companies

E-commerce Innovators Fund

Invests in cutting-edge e-commerce technologies and AI-driven solutions to streamline online retail platforms.

  • Other
  • AI / ML
  • Consumer
  • Pre-Seed
  • $1.0M – $4.0M
  • Chicago, IL
  • 1 portfolio company

Echo Capital Partners

Investing in promising SaaS startups in the Midwest, focusing on innovative B2B solutions.

  • SaaS
  • Seed
  • $2.0M – $4.0M
  • Chicago, IL

Ecom Sprint Fund

Focused on early-stage companies revolutionizing the e-commerce landscape through technological advancements.

  • Other
  • Pre-Seed
  • $250K – $600K
  • Chicago, IL
  • 1 portfolio company

EcomFund Ventures

Focused on investing in early-stage startups solving innovative problems within the e-commerce industry.

  • Other
  • Seed
  • $750K – $2.5M
  • Chicago, IL

Ecommerce Ecosystem Fund

Investing in innovative e-commerce platform solutions and marketplaces that optimize local and sustainable commerce.

  • Other
  • Marketplace
  • Pre-Seed, Seed
  • $250K – $1.0M
  • Chicago, IL
  • 1 portfolio company

Showing 169–192 of 717 firms — page 8 of 30.

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