Pearl Avenue Partners — Seed VC Firm ($300K–$1.5M Checks)
Pearl Avenue Partners is a Seed venture capital firm based in Chicago, IL investing in Healthcare, SaaS, AI / ML. The firm typically writes $300K–$1.5M checks and has 2 portfolio companies in our records.
- Check size
- $300K–$1.5M
- Portfolio
- 2 companies on record
- Stage
- Seed
- Sectors
- Healthcare, SaaS, AI / ML, Enterprise
- HQ
- Chicago, IL
- AUM
- Not in our records
Last verified: 2026-05-21
Seed
$300K – $1.5M
2+ companies
Investment Thesis
Pearl Avenue Partners invests in early-stage technology companies streamlining enterprise health services with AI.
How Pearl Avenue Partners invests
Pearl Avenue Partners is a vc firm based in Chicago, IL. The firm invests at the Seed stage, with a focus on Healthcare, SaaS, AI / ML, Enterprise. It does not invest in Direct retail.
Pearl Avenue Partners typically writes checks of $300K–$1.5M per investment.
Pearl Avenue Partners has backed 2 companies in our records, including OrthoAI, PayerLogic.
Industry Focus
Invests In
Does Not Invest In
Portfolio Companies (2)
Other
OrthoAI
PayerLogic
- •Raising at Seed? You're squarely in their sweet spot.
- •Lead with your fit in Healthcare, SaaS, AI / ML — the sectors they actively back.
- •Size your ask to their typical $300K – $1.5M check.
- •cold outreach ok
- •A warm introduction beats a cold email. Get matched and request an intro.
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