PI

Pioneer One Ventures

VC
Chicago, ILWebsite
How to approach: warm intro preferred
Stage

Pre-Seed

Check Size

$100K – $1.0M

Portfolio

27+ companies

Team

7 partners

Investor activity
Investments in last 12 months: 0

Investment Thesis

A sector-agnostic micro fund emphasizing deep data platforms and SaaS applications bringing new paradigms in healthcare and enterprise tech.

Meet the Team

CS

Christina Senft

Innovation Manager

SS

Sophie Sorg

Innovation Manager

TG

Thomas Gabriel

Managing Partner

AS

Anton Schilling

Managing Partner

SK

Sophia Kuther

Innovation Manager

JK

Julian König

Manager

RH

Rachel Hayes

Sole GP

Pre-Seed
B2B SaaS

Industry Focus

Invests In

SaaS
Healthcare
Other
Developer Tools
Enterprise

Portfolio Companies (27)

Other

DA

DataPredict AI

Healthcare Data Analytics
BE

Bea Fertility

Digital Health/Therapeutics·Seed

Fertility treatment platform using AI and biotech.

BI

BioAscent Discovery Limited

Discovery Services·Seed

Drug discovery and development services.

BI

Bio-Images Drug Delivery Limited

Medical Technologies·Seed

Drug delivery via imaging tech.

BI

BiVictrix Therapeutics Plc

Therapeutics·Seed (public now)

Bispecific antibody therapeutics for cancer.

EN

EnteroBiotix

Therapeutics·Seed

Microbiome therapeutics for gut disorders.

FA

FasTBioPharma

Discovery Services·Pre-Seed/Seed

Rapid biologics manufacturing platform.

GE

Genxt Network

Digital Health/Pharma Tech·Seed

AI-driven next-gen biotech network (inferred).

IM

ImmuONE Limited

Diagnostics/Discovery·Seed

Human lung organ-on-chip for drug testing.

KI

Kinomica Limited

Therapeutics/Discovery·Seed

Kinase biology platform for drug discovery.

How to pitch Pioneer One Ventures
  • Raising at Pre-Seed? You're squarely in their sweet spot.
  • Lead with your fit in SaaS, Healthcare, Other — the sectors they actively back.
  • Size your ask to their typical $100K – $1.0M check.
  • warm intro preferred
  • Address your outreach to a specific partner, such as Christina Senft, Innovation Manager.
  • A warm introduction beats a cold email. Get matched and request an intro.

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