PI

Pioneer One Ventures

VC
Chicago, ILWebsite

Pioneer One Ventures is a Pre-Seed venture capital firm based in Chicago, IL investing in SaaS, Healthcare, Other. The firm typically writes $100K–$1.0M checks and has 27 portfolio companies in our records.

Check size
$100K–$1.0M
Portfolio
27 companies on record
Partners
7 listed
Stage
Pre-Seed
Sectors
SaaS, Healthcare, Other, Developer Tools, Enterprise
HQ
Chicago, IL
AUM
Not in our records

Last verified: 2026-07-08

How to approach: warm intro preferred
Stage

Pre-Seed

Check Size

$100K – $1.0M

Portfolio

27+ companies

Team

7 partners

Investor activity
Investments in last 12 months: 0

Investment Thesis

A sector-agnostic micro fund emphasizing deep data platforms and SaaS applications bringing new paradigms in healthcare and enterprise tech.

How Pioneer One Ventures invests

Pioneer One Ventures is a vc firm based in Chicago, IL. The firm invests at the Pre-Seed stage, with a focus on SaaS, Healthcare, Other, Developer Tools, Enterprise.

Pioneer One Ventures typically writes checks of $100K–$1.0M per investment.

Pioneer One Ventures has backed 27 companies in our records, including DataPredict AI, Bea Fertility, BioAscent Discovery Limited.

Partners & Team

AS

Anton Schilling

Managing Partner

SS

Sophie Sorg

Innovation Manager

TG

Thomas Gabriel

Managing Partner

SK

Sophia Kuther

Innovation Manager

JK

Julian König

Manager

RH

Rachel Hayes

Sole GP

Pre-Seed
B2B SaaS
CS

Christina Senft

Innovation Manager

Industry Focus

Invests In

SaaS
Healthcare
Other
Developer Tools
Enterprise

Portfolio Companies (27)

Other

DA

DataPredict AI

Healthcare Data Analytics
BE

Bea Fertility

Digital Health/Therapeutics·Seed

Fertility treatment platform using AI and biotech.

BI

BioAscent Discovery Limited

Discovery Services·Seed

Drug discovery and development services.

BI

Bio-Images Drug Delivery Limited

Medical Technologies·Seed

Drug delivery via imaging tech.

BI

BiVictrix Therapeutics Plc

Therapeutics·Seed (public now)

Bispecific antibody therapeutics for cancer.

EN

EnteroBiotix

Therapeutics·Seed

Microbiome therapeutics for gut disorders.

FA

FasTBioPharma

Discovery Services·Pre-Seed/Seed

Rapid biologics manufacturing platform.

GE

Genxt Network

Digital Health/Pharma Tech·Seed

AI-driven next-gen biotech network (inferred).

IM

ImmuONE Limited

Diagnostics/Discovery·Seed

Human lung organ-on-chip for drug testing.

KI

Kinomica Limited

Therapeutics/Discovery·Seed

Kinase biology platform for drug discovery.

How to pitch Pioneer One Ventures
  • Raising at Pre-Seed? You're squarely in their sweet spot.
  • Lead with your fit in SaaS, Healthcare, Other — the sectors they actively back.
  • Size your ask to their typical $100K – $1.0M check.
  • warm intro preferred
  • Address your outreach to a specific partner, such as Anton Schilling, Managing Partner.
  • A warm introduction beats a cold email. Get matched and request an intro.

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