TW

Twine Ventures — Pre-Seed & Seed VC Firm

VC

Twine Ventures is a Pre-Seed, Seed venture capital firm investing in Healthcare, Other, Fintech. The firm has 33 portfolio companies in our records.

Portfolio
33 companies on record
Partners
3 listed
AUM
$100M
Stage
Pre-Seed, Seed
Sectors
Healthcare, Other, Fintech, Developer Tools, AI / ML, SaaS
Check size
Not in our records

Last verified: 2026-10-24

How to approach: warm intro preferred
Stage

Pre-Seed, Seed

AUM

$100M

Portfolio

33+ companies

Team

3 partners

Investor activity
Investments in last 12 months: 0

Investment Thesis

An early-stage investor with direct involvement in a wearable-data-enabled clinical SaaS round. The firm appears comfortable with products that connect consumer health data to providers.

How Twine Ventures invests

Twine Ventures is a vc firm. The firm invests at the Pre-Seed, Seed stages, with a focus on Healthcare, Other, Fintech, Developer Tools, AI / ML.

Twine Ventures manages approximately $100M in assets. Our records include 2 funds raised by the firm.

Twine Ventures has backed 33 companies in our records, including Airship, Alaffia, Alchemy.

Partners & Team

U

Unknown

Partner

Clinical SaaS
Wearable data
LS

Leshika Samarasinghe

Founder

early-stage
health
climate

Dedicated career to supporting mission-driven founders building at the earliest stages: early product team at Google, founding member of the Advanced Research Projects Agency for Energy (ARPA-E), and Managing Partner at The Production Board, a venture studio founding companies in health and climate. She loves to partner with founders on GTM strategies and driving competitive Series A fundraises.

EY

Ethan Yeh, PhD

Managing Partner

data science
technology startups
policy
government
academic research

Data science leader turned investor. Former Head of Data Science at Stripe, director at Twitter, and health economist at the World Bank. His work has spanned technology startups, policy, government, and academic research. As an operator and investor, he has supported teams from inception to IPO.

Industry Focus

Invests In

Healthcare
Other
Fintech
Developer Tools
AI / ML
SaaS

Funds

Twine Ventures Fund II

$150M2021
actively investing

Twine Ventures Fund I

$100M2019
fully deployed

Portfolio Companies (33)

Other

AI

Airship

Industrials

Sales enablement software for HVAC professionals

AL

Alaffia

Healthcare

AI-based payment integrity that lowers health costs

AL

Alchemy

Healthcare

Tech-enabled pharmacy for underserved populations

AL

Alden

Healthcare
AL

Alpha Grid

Industrials

Pricing intelligence for EV charging infrastructure

AP

Apella

Healthcare
AT

Atrix

Healthcare
AV

Ava

Fintech / Data
CL

CloudCruise

Healthcare
CO

Colla Health

Healthcare
How to pitch Twine Ventures
  • •Raising at Pre-Seed, Seed? You're squarely in their sweet spot.
  • •Lead with your fit in Healthcare, Other, Fintech — the sectors they actively back.
  • •warm intro preferred
  • •Address your outreach to a specific partner, such as Unknown, Partner.
  • •A warm introduction beats a cold email. Get matched and request an intro.

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