AI Investors Backing the Next Generation of Models

AI founders need investors who can tell a durable advantage from a thin wrapper. We match you with VCs actively funding machine learning and applied AI — people who understand model economics, data moats, and how technical products reach customers.

AI & ML Investors at a Glance

Active Investors

126

Avg Check Size

$6.1M

Featured Firms

24+

Featured AI & ML Investors

PO

Point72 Ventures

New York, NY

Invests in enterprise software and AI with strong data orientation; can lead or co-lead early rounds.

seed
$1M–$10M164 investments

Portfolio: Hyperscience, Domino Data Lab, Cedar

E1

E14 Fund

Cambridge, MA

E14 Fund invests in MIT-founded or MIT-affiliated startups focused on deep tech and enterprise solutions, emphasizing AI and practical applications.

pre-seed
seed
$75K–$500K101 investments

Portfolio: Perceptive Automata, Overjet, Mosaic ML

HI

High Alpha

Indianapolis, IN, USA

B2B SaaS specialist with strong operator DNA. Focused on sales org productivity and enablement AI with clear GTM buyer.

seed
series-a
$1M–$5M99 investments

Portfolio: AudiencePlus, Authenticx, Backstroke

AL

Alpaca VC

Boston, MA

Seed-stage fund investing in B2B SaaS and vertical software with clear ROI and repeatable GTM.

pre-seed
Seed
$500K–$2M91 investments

Portfolio: Buoy Health, TraceLink, Compass

AQ

AQC Capital

Montreal, Canada

Supports high-tech companies innovating in semiconductors, wireless RF systems, and advanced industrial processes.

seed
$750K–$2.5M70 investments

Portfolio: Xanadu Quantum, Infinera, AAVAA

AR

Archetype Ventures

San Francisco, CA

Invests in founders building tech models that solve global and systemic challenges, including AI and analytics for enterprise applications.

pre-seed
seed
$250K–$2M66 investments

Portfolio: Tractable, Passthrough, KENCOPA

WI

Wisconsin Alumni Research Foundation (WARF Ventures)

Madison, WI

Supports commercialization of UW–Madison innovations and Wisconsin-based technology startups, including deep tech and materials-derived IP.

pre-seed
seed
$250K–$2M65 investments

Portfolio: Virent Inc., NeuWave Medical (historic WARF-related), Exact Sciences (historic Wisconsin ecosystem)

DE

Deep Tech Ventures

Berlin, Germany

Investment arm designed for pioneering companies in the deeptech fields such as infrastructure and AI/ML systems with high barriers-to-entry.

pre-seed
seed
$500K–$2M63 investments

Portfolio: ENS, SPL, Hardhat

DE

Deep Blue Ventures

Los Angeles, CA

Invest in pioneering Maritime and Defense Technologies transforming surveillance and security.

pre-seed
$1M–$3M60 investments

Portfolio: Nautical AI, Advantage Club, Allocations

NE

Neotribe Ventures

Palo Alto, CA

Focus on deep tech startups creating unconventional and disruptive solutions at the intersection of hardware, AI infrastructure, and advanced materials.

early stage
series-a
$500K–$7M59 investments

Portfolio: Lightmatter, Grady, BigUp

PA

Particle VC

Austin, TX

Focuses exclusively on cutting-edge materials innovation and hardware technologies for next-gen computing and connectivity.

pre-seed
seed
$500K–$3M50 investments

Portfolio: BiiLabs, Affirm, Axonius

AI

AI Seed

London, United Kingdom

Invests in early-stage AI companies with a focus on applied AI solutions for enterprises.

pre-seed
$250K–$1.5M46 investments

Portfolio: 9fin, ai Build, Causalens

PU

Purpose Ventures

San Francisco, USA

Investing in early-stage purpose-driven AI and DeepTech companies solving global challenges.

pre-seed
$250K–$1M45 investments

Portfolio: Element AI, Seldon, OPV Social Equity I, LLC (CIK 0001817969)

AL

Alumni Ventures

Manchester, NH

Multi-fund platform investing in venture-backed startups at seed and beyond, often co-investing in priced seed rounds.

seed
Series A
$250K–$3M34 investments

Portfolio: Hims & Hers, OpenAI, Oura

AT

Atomix Ventures

Austin, TX

Atomix Ventures focuses on deep tech startups innovating in semiconductors, advanced materials, and cutting-edge computing hardware.

pre-seed
seed
$500K–$2M33 investments

Portfolio: Hims & Hers, OpenStore, Bungalow

QU

Quantum Wave Ventures

Los Altos, CA

Focuses on startups driving innovation in semiconductors, materials science, and quantum-enabling technologies.

pre-seed
seed
$500K–$3M33 investments

Portfolio: Kvantify, Wave Photonics, Multiverse Computing

AI

Air Street Capital

London, UK

AI-first venture capital fund investing in machine learning companies from pre-seed onward, including applied AI in vertical workflows.

pre-seed
Seed
$500K–$3M32 investments

Portfolio: Faculty, Chattermill, Clove

AQ

AquaTech Ventures

San Diego, CA

AquaTech Ventures specializes in supporting maritime technology startups that leverage deep technology to transform traditional marine operations.

pre-seed
seed
$750K–$2.5M32 investments

Portfolio: Naval Innovations Inc., BioMOD™ Anaerobic Membrane Bioreactor, BioMOD™ Dissolved Air Flotation

BI

Big Pi Ventures

Boston, MA

Big Pi Ventures invests in IP-driven startups developing scientific breakthroughs, with a strong interest in healthcare and biotech.

pre-seed
seed
$500K–$3M31 investments

Portfolio: Concerto HealthAI, IntelyCare, Audio software

TW

Two Sigma Ventures

US-NYC

Investing in data-driven companies solving hard problems.

seed
series-a
series-b
$1M–$25M30 investments

Portfolio: Amper Music, Anomalo, Ansel Health

SP

Spark Capital

US-SF

We believe in the founders who build the future.

seed
series-a
$1M–$20M30 investments

Portfolio: Discord, Anthropic, Plaid

RA

Radical Ventures

Toronto, Canada

AI-focused venture firm backing applied and foundational AI companies, including vertical applications.

Seed
$500K–$5M30 investments

Portfolio: Waabi, Ribbon, Crusoe

UN

Union Square Ventures

US-NYC

Thesis-driven venture capital. Investing at the intersection of emerging networks and public benefit.

seed
series-a
$1M–$25M30 investments

Portfolio: Pluralis, Humane Genomics, Electroflow

SC

Scale Venture Partners

US-SF

Partner with category-defining enterprise software companies.

series-a
series-b
$5M–$40M29 investments

Portfolio: Bill.com, JFrog, Box

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