Series B Venture Capital Firms

Lux Capital invests in frontier science and deep‐tech founders, backing radical breakthroughs at the intersection of physical, life, and computational sciences, from very early (inception/seed) throug...

• Deep Tech
• Other
• Climate / Energy

• Seed, Series A, Series B
• $100K – $100.0M
• New York, United States
• 9 portfolio companies

Menlo Ventures invests at every early-to-growth stage—pre-seed, seed, Series A/B and inflection—in AI, consumer, enterprise, healthcare and frontier technologies, backing founder-led teams seeking pro...

• Enterprise
• Consumer
• Healthcare

• Seed, Series A, Series B
• $100K – $30.0M
• Menlo Park, California, United States
• 10 portfolio companies

Saudi investment firm focused on AI, software, fintech, and digital infrastructure. Helpful for later pre-seed or seed-stage discussions if the startup becomes infrastructure-like decision software fo...

• AI / ML
• Other
• Healthcare

• Seed, Series A, Series B
• Riyadh, Saudi Arabia
• 44 portfolio companies

Global Web3 investor backing founders and emerging fund managers across the crypto ecosystem. The firm is active from pre-seed through Series C and is oriented around infrastructure and ecosystem inve...

• Other

• Pre-Seed, Seed, Series A, Series B, series-c
• $1.0M – $40.0M

Focuses on scaling AI-driven enterprise and automation solutions across Europe.

• Enterprise
• Other
• AI / ML

• Seed, Series A, Series B
• $1.0M – $10.0M
• London, UK
• 2 portfolio companies

Investing in innovative startups unlocking new efficiencies in automotive, AI-grade hardware, and mobility sectors.

• Other
• AI / ML

• Series A, Series B
• $3.0M – $15.0M
• Boston, MA
• 7 portfolio companies

New Enterprise Associates - one of the world's largest and most active venture capital firms.

• Healthcare
• Enterprise
• Consumer

• Seed, Series A, Series B, Growth
• $500K – $100.0M
• US-SF
• 4 portfolio companies

Supporting next-generation technologies in healthcare focused on AI and scalable enterprise solutions.

• Healthcare
• Other
• Enterprise

• Series B
• $2.0M – $40.0M
• Austin, TX
• 2 portfolio companies

Growth-stage investor focused on market-leading companies.

• Enterprise
• Healthcare
• Consumer

• Series A, Series B, Growth
• $5.0M – $75.0M
• US-SF

Backs breakthrough technologies addressing the root causes of climate change, with a focus on scalable science-led solutions for emissions reductions.

• Other

• Seed, Series A, Series B
• $500K – $5.0M
• Cambridge, MA
• 44 portfolio companies

Life science venture fund focused on early-stage investments in life science tools, molecular diagnostics and innovative therapeutics, with emphasis on genomics, proteomics and next-gen analytical equ...

• Other
• Consumer
• Real Estate

• Series A, Series B, early-growth
• Palo Alto, California
• 8 portfolio companies

Focus on Blockchain protocols optimized for institutional-grade security, including quantum resistance and interoperable financial primitives.

• Other

• Series A, Series B
• $1.0M – $10.0M
• Singapore
• 2 portfolio companies

We partner with founders at every stage to build transformative companies.

• Enterprise
• Consumer
• Developer Tools

• Seed, Series A, Series B
• $1.0M – $30.0M
• US-SF
• 15 portfolio companies

Invests in startups improving safety, security, and operational resilience using AI and advanced technologies.

• Other

• Series A, Series B
• $2.0M – $20.0M
• Boston, MA
• 8 portfolio companies

Rethink Education invests in technologies that improve access, equity, and outcomes in education. It is a strong fit for seed-stage EdTech B2B SaaS with measurable impact in learning operations.

• EdTech
• Other

• Seed, Series A, Series B
• $500K – $5.0M
• New York, New York

Focused exclusively on fintech and crypto. We back founders reinventing financial services.

• Fintech
• Other

• Seed, Series A, Series B
• $1.0M – $50.0M
• US-SF
• 30 portfolio companies

Specializes in funding software solutions that mitigate operational risks in automated systems, particularly in health and industrial sectors.

• Other
• SaaS
• AI / ML

• Series A, Series B
• $2.0M – $20.0M
• New York City, NY
• 2 portfolio companies

Corporate venture fund of Ryder focused exclusively on technologies driving innovation in fleet management, transportation, and logistics operations.

• Other
• Deep Tech

• seed+, Series A, Series B
• $1.0M – $10.0M
• Miami, FL
• 1 portfolio company

Large Saudi technology investor with AI and software focus. More of a later-stage option, but relevant for strategic regional scaling if the startup quickly proves club demand.

• AI / ML
• SaaS
• Enterprise

• Seed, Series A, Series B
• Riyadh, Saudi Arabia
• 12 portfolio companies

Supports SaaS companies redefining enterprise operations, with a keen interest in cross-border platforms.

• SaaS

• Series A, Series B
• $750K – $4.0M
• San Francisco, CA
• 1 portfolio company

Dedicated health-tech fund investing in digital health, bio-convergence, and medical devices for Israeli-related startups in Israel and abroad. Positioned as a specialist platform with a portfolio spa...

• Healthcare
• Other
• AI / ML

• Seed, Series A, Series B, series-c
• 22 portfolio companies

Global technology investment firm focused on enterprise software.

• Enterprise
• Healthcare
• Fintech

• Series A, Series B, Growth
• $5.0M – $50.0M
• US-SF
• 66 portfolio companies

Partner with category-defining enterprise software companies.

• Enterprise
• SaaS
• Developer Tools

• Series A, Series B
• $5.0M – $40.0M
• US-SF
• 29 portfolio companies

Sequoia invests across seed, early and growth‐stage technology companies—especially those solving large problems with exceptional founders, strong product/market fit, and markets that can scale to sig...

• Consumer
• Enterprise
• Fintech

• Seed, Series A, Series B
• $500K – $200.0M
• Menlo Park, United States
• 19 portfolio companies