Sigma Prime Ventures
Sigma Prime Ventures is a Seed, Series A venture capital firm based in Boston, MA investing in AI / ML, Healthcare, Enterprise. The firm typically writes $1.0M–$5.0M checks and has 34 portfolio companies in our records.
Seed, Series A
$1.0M – $5.0M
34+ companies
7 partners
Investment Thesis
Focuses on innovative companies that leverage technology to transform their industries, with a strong interest in digital health innovations.
How Sigma Prime Ventures invests
Sigma Prime Ventures is a vc firm based in Boston, MA. The firm invests at the Seed, Series A stages, with a focus on AI / ML, Healthcare, Enterprise, SaaS, Developer Tools. It does not invest in Consumer Products.
Sigma Prime Ventures typically writes checks of $1.0M–$5.0M per investment.
Sigma Prime Ventures has backed 34 companies in our records, including Wellframe, Imprivata, acquia.
Meet the Team
Jere Doyle
Managing Director
John Simon
Managing Partner
David Slatkin
Managing Partner
Before we were venture capitalists, we were entrepreneurs. As entrepreneurs, our team founded 10 companies... ...ran 10 companies as operators and executives... ...responsible for exits worth over $4.2B.
Michael Strollo
Principal
Before we were venture capitalists, we were entrepreneurs. As entrepreneurs, our team founded 10 companies... ...ran 10 companies as operators and executives... ...responsible for exits worth over $4.2B.
Daniel Ghausi
Principal
Before we were venture capitalists, we were entrepreneurs. As entrepreneurs, our team founded 10 companies... ...ran 10 companies as operators and executives... ...responsible for exits worth over $4.2B.
Ryan Smith
Principal
Before we were venture capitalists, we were entrepreneurs. As entrepreneurs, our team founded 10 companies... ...ran 10 companies as operators and executives... ...responsible for exits worth over $4.2B.
Sigma Prime Fellows
Fellow
We Are You We have been in your shoes as entrepreneurs. Our team has founded 10 companies, helped run 10 companies, and collectively been responsible for exits worth over $4.2B in those companies where we were founders and operators.
Industry Focus
Invests In
Does Not Invest In
Portfolio Companies (34)
Other
Wellframe
Imprivata
acquia
aPriori
barkly
BlueConic
CallMiner
CarNow
Ceros
CloudHealth Technologies
- •Raising at Seed, Series A? You're squarely in their sweet spot.
- •Lead with your fit in AI / ML, Healthcare, Enterprise — the sectors they actively back.
- •Size your ask to their typical $1.0M – $5.0M check.
- •warm intro preferred
- •Address your outreach to a specific partner, such as Jere Doyle, Managing Director.
- •A warm introduction beats a cold email. Get matched and request an intro.
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