Venture Capital Firms in San Francisco

Browse 1,273 venture capital firms headquartered in San Francisco. Median check across the 1246 firms that disclose a range is $500K–$2.5M; most active at Seed, Pre-Seed, Series A; concentrated in SaaS, AI / ML, Enterprise. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified San Francisco VC firms

DeFi Ventures Fund

Invests in decentralized finance projects and technologies that aim to reshape the financial landscape, with a strong focus on community building.

  • Other
  • Pre-Seed
  • $50K – $200K
  • San Francisco, CA
  • 1 portfolio company

Decentral Labs Capital

Invests in infrastructure and enterprise software enabling decentralized systems, including multi-cloud and hybrid environments.

  • Other
  • AI / ML
  • Developer Tools
  • Pre-Seed, Seed
  • $500K – $3.0M
  • San Francisco, CA
  • 17 portfolio companies

Decoded Ventures

Focused on cutting-edge AI and blockchain innovations that drive operational efficiencies and financial system transformation.

  • AI / ML
  • Other
  • Developer Tools
  • Seed
  • $1.0M – $8.0M
  • San Francisco, CA
  • 4 portfolio companies

DeepAlpha Capital

Partners with startups building sophisticated AI tools to give asset managers predictive insights and hyper-efficient research workflows.

  • Other
  • SaaS
  • Seed, Series A
  • $500K – $3.0M
  • San Francisco, CA
  • 1 portfolio company

DeepSpace Ventures

Invests in emerging technologies transforming enterprise infrastructure, particularly data centers and AI platforms.

  • Other
  • AI / ML
  • Fintech
  • Pre-Seed, Seed
  • $750K – $2.5M
  • San Francisco, CA
  • 5 portfolio companies

Defensive AI Ventures

Focused on cybersecurity and AI safety solutions for enterprise applications.

  • Security
  • Other
  • Seed
  • $1.0M – $7.0M
  • San Francisco, CA

Define Ventures

Specializes in early-stage digital health companies focused on transforming healthcare delivery and technology solutions.

  • Healthcare
  • Seed, Series A
  • $1.5M – $10.0M
  • San Francisco, CA
  • 8 portfolio companies

DeltaForge Ventures

DeltaForge Ventures supports startups solving enterprise workflow inefficiencies, especially in B2B SaaS and fintech.

  • Fintech
  • SaaS
  • Healthcare
  • Pre-Seed
  • $750K – $3.5M
  • San Francisco, CA
  • 2 portfolio companies

Dental Innovation Fund

Sector-focused fund investing exclusively in dental-focused startups with cutting-edge technology solutions.

  • Other
  • Healthcare
  • AI / ML
  • Pre-Seed, Seed
  • $500K – $2.0M
  • San Francisco, CA
  • 1 portfolio company

Designer Fund

Invests in design-driven companies focused on consumer products and experiences.

  • Other
  • Pre-Seed, Seed
  • $100K – $1.0M
  • San Francisco, CA
  • 111 portfolio companies

DevBase Ventures

Focused on backing developer tools and infrastructure innovations that enhance productivity and scalability.

  • Developer Tools
  • Enterprise
  • Other
  • Seed
  • $250K – $5.0M
  • San Francisco, CA
  • 42 portfolio companies

DevCraft Capital

DevCraft Capital funds startups building next-generation developer tools and platforms to accelerate software efficiency and productivity.

  • Developer Tools
  • SaaS
  • AI / ML
  • Pre-Seed, Seed
  • $200K – $2.0M
  • San Francisco, CA
  • 2 portfolio companies

Developer Centric Capital

Invests in pre-seed startups creating tools for developers, aiming to enhance developer productivity and integration.

  • Developer Tools
  • SaaS
  • Pre-Seed
  • $500K – $2.5M
  • San Francisco, CA

Developer First Capital

Focused exclusively on early-stage developer tools and technical B2B SaaS startups that improve workflow productivity.

  • Developer Tools
  • SaaS
  • Pre-Seed, Seed
  • $250K – $2.0M
  • San Francisco, CA

DeviceFlow Investors

Early-stage fund focusing on consumer electronics platforms, particularly those innovating in device lifecycle management.

  • Other
  • Marketplace
  • Pre-Seed
  • $50K – $250K
  • San Francisco, CA
  • 1 portfolio company

Digital Defense Capital

Targets cutting-edge cybersecurity firms solving cloud security challenges.

  • Security
  • Other
  • Seed
  • $1.0M – $4.0M
  • San Francisco, CA
  • 1 portfolio company

Digital Harmony Partners

Invests in early-stage companies revolutionizing music through technology, emphasizing scalable SaaS platforms.

  • Other
  • SaaS
  • Pre-Seed
  • $1.0M – $2.5M
  • San Francisco, CA
  • 1 portfolio company

Digital Health Propulsion

Supports emerging startups in digital health that are redefining healthcare management and delivery.

  • Healthcare
  • Pre-Seed, Seed
  • $60K – $250K
  • San Francisco, CA
  • 1 portfolio company

Digital Impact Fund

Invests in startups driving digital transformation across sectors, with a focus on impactful technology solutions.

  • Other
  • Seed
  • $300K – $2.0M
  • San Francisco, CA
  • 1 portfolio company

Digital Innovators Fund

Focuses on digital-first businesses that empower solo entrepreneurs and small teams with innovative SaaS and marketplace solutions.

  • SaaS
  • Marketplace
  • Other
  • Seed, Pre-Seed
  • $1.0M – $3.0M
  • San Francisco, CA

Digital Rails Ventures

Focused on API-driven platforms in the financial sector, aiming to streamline integration and API efficiencies.

  • Developer Tools
  • Fintech
  • SaaS
  • Pre-Seed
  • Up to $2.5M
  • San Francisco, CA

Digital Supply Partners

Accelerating digital transformation within supply chain and logistics industries.

  • Other
  • SaaS
  • Marketplace
  • Seed
  • $1.2M – $4.0M
  • San Francisco, CA
  • 1 portfolio company

Digital Twin Ventures

Focused exclusively on investing in early-stage companies in the digital twin and simulation space.

  • SaaS
  • Other
  • AI / ML
  • Pre-Seed
  • $250K – $500K
  • San Francisco, CA

Disclosure Capital

Disclosure Capital invests in data-centric startups leveraging AI/ML to solve complex industry-specific problems.

  • AI / ML
  • Developer Tools
  • Other
  • Pre-Seed, Seed
  • $200K – $2.0M
  • San Francisco, CA
  • 2 portfolio companies

Showing 361–384 of 1273 firms — page 16 of 54.

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