IndieBio
IndieBio is a Pre-Seed, Seed venture capital firm based in San Francisco, CA investing in Other, Deep Tech, Climate / Energy. The firm typically writes $250K–$2.0M checks and has 12 portfolio companies in our records.
- Check size
- $250K–$2.0M
- Portfolio
- 12 companies on record
- Partners
- 11 listed
- AUM
- $1.5B
- Stage
- Pre-Seed, Seed
- Sectors
- Other, Deep Tech, Climate / Energy, Healthcare
- HQ
- San Francisco, CA
Last verified: 2026-05-30
Pre-Seed, Seed
$250K – $2.0M
$1.5B
12+ companies
11 partners
Investment Thesis
Focus on early-stage biotech and deeptech companies transforming human and planetary health.
How IndieBio invests
IndieBio is a vc firm based in San Francisco, CA. The firm invests at the Pre-Seed, Seed stages, with a focus on Other, Deep Tech, Climate / Energy, Healthcare.
IndieBio typically writes checks of $250K–$2.0M per investment, backed by approximately $1.5B in assets under management.
Investing since at least 2015, IndieBio has backed 12 companies in our records, including Afynia, Calder Biosciences, Gozen Bioworks. Its most recent recorded investment was in 2023.
Partners & Team
Arvind Gupta
GP
Bill Liao
Venture Partner, SOSV
Industry Focus
Invests In
Portfolio Companies (12)
2023
Afynia
Trusted source for information & easy-to-use products for women’s health conditions
Calder Biosciences
Creating Next-Generation Vaccines to Protect Against Infection
2022
Gozen Bioworks
Animal free leather with unprecedented strength, look, and feel.
Hoofprint Biome
Hoofprint Biome represents a new paradigm in solving methane emissions from cattle.
2021
Canaery
Identifying the chemical world through scent
Puna Bio
Growing crops in impossible conditions
Protonintel
Know yourself
RizLab Health
Bringing blood analysis to patients’ fingertips
2020
Cayuga Biotech
Biomimetic solutions for hemorrhage control
2015
Zymochem
Sustainable Materials using patented Carbon-Conserving (C2) microbes
- •Raising at Pre-Seed, Seed? You're squarely in their sweet spot.
- •Lead with your fit in Other, Deep Tech, Climate / Energy — the sectors they actively back.
- •Size your ask to their typical $250K – $2.0M check.
- •warm intro preferred
- •Address your outreach to a specific partner, such as Deborah Zajac, General Partner, SOSV and IndieBio NY.
- •A warm introduction beats a cold email. Get matched and request an intro.
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