25madison — Seed VC Firm ($250K–$1.0M Checks)
25madison is a Seed venture capital firm based in New York, New York investing in SaaS, Other, AI / ML. The firm typically writes $250K–$1.0M checks and has 42 portfolio companies in our records.
- Check size
- $250K–$1.0M
- Portfolio
- 42 companies on record
- Partners
- 9 listed
- AUM
- $500M
- Stage
- Seed
- Sectors
- SaaS, Other, AI / ML, Healthcare, Enterprise
- HQ
- New York, New York
Last verified: 2026-10-21
Seed
$250K – $1.0M
$500M
42+ companies
9 partners
Investment Thesis
25madison builds and backs companies across B2B software and operations-heavy categories. Its seed check sizes and company-building approach suit a logistics-services business with proprietary software.
How 25madison invests
25madison is a vc firm based in New York, New York. The firm invests at the Seed stage, with a focus on SaaS, Other, AI / ML, Healthcare, Enterprise.
25madison typically writes checks of $250K–$1.0M per investment, backed by approximately $500M in assets under management. Our records include 1 fund raised by the firm.
25madison has backed 42 companies in our records, including April Health, Basalt Health, Canopy.
Partners & Team
Industry Focus
Invests In
Funds
Fund III
Portfolio Companies (42)
Other
April Health
A fully-integrated, turnkey behavioral health solution that improves patient outcomes, reduces provider burden, and generates new revenue streams for your practice.
Basalt Health
The AI-powered health care assistant
Canopy
Wearable personal safety technology and location services for healthcare staff
Clear
Comprehensive pricing and payments platform for healthcare
Clearpol
Compliance Management Platform for healthcare facilities
Croissant
Get a guaranteed resale value before you buy.
Eon
Natural language processing for Radiology Reports
Flourish
Virtual mental health care for teens and young adults with serious mental health conditions
Rebuild
Rebuild uses artificial intelligence to double the speed of estimators. Accurate, insurance-compliant estimates in a fraction of the time.
Recourse
Claims intelligence for healthcare providers
- •Raising at Seed? You're squarely in their sweet spot.
- •Lead with your fit in SaaS, Other, AI / ML — the sectors they actively back.
- •Size your ask to their typical $250K – $1.0M check.
- •warm intro preferred
- •Address your outreach to a specific partner, such as Laura Evans, Director.
- •A warm introduction beats a cold email. Get matched and request an intro.
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