Seed Venture Capital Firms

Focuses on pioneering innovations in healthcare and life sciences, with an emphasis on breakthrough therapies and biotech platforms.

• Healthcare
• Other
• SaaS

• Seed
• $500K – $3.0M
• San Francisco, CA
• 67 portfolio companies

Focuses exclusively on regulated sectors like healthcare and insurance, backing startups providing compliance frameworks using AI and advanced SaaS tools.

• Other
• Healthcare
• SaaS

• Pre-Seed, Seed
• $500K – $2.5M
• Chicago, IL
• 1 portfolio company

Focuses exclusively on secondary and tertiary markets for real estate and home services tech startups that can support local economies.

• Real Estate
• Other

• Pre-Seed, Seed
• $50K – $500K
• Madison, WI
• 1 portfolio company

Focused on early-stage startups in B2B SaaS and Marketplace sectors; supports founders solving complex business problems through software innovation.

• SaaS
• Marketplace
• Fintech

• Seed
• $1.0M – $3.0M
• Austin, TX
• 17 portfolio companies

Dedicated to supporting HealthTech startups that leverage AI to improve healthcare efficiencies and outcomes.

• Healthcare
• AI / ML
• SaaS

• Pre-Seed, Seed
• $25K – $150K
• Charleston, SC
• 41 portfolio companies

Class 5 Global invests in cloud/software infrastructure for education and learning, with a practical seed-stage thesis. It is a niche fund with strong relevance to B2B EdTech infrastructure companies.

• EdTech
• Other

• Seed
• $250K – $1.5M

Clave Capital partners with early-stage startups solving specific LatAm issues in cybersecurity and enterprise SaaS.

• Security
• SaaS
• Other

• Pre-Seed, Seed
• $100K – $1.2M
• Bogotá, Colombia
• 1 portfolio company

Claybon Capital targets scalable marketplace solutions, particularly those tapping into the burgeoning digital collectibles space.

• Other
• Marketplace

• Pre-Seed, Seed
• $150K – $500K
• Raleigh, NC
• 1 portfolio company

Focuses on innovative CleanTech startups with breakthrough solutions addressing climate change challenges, specifically looking for companies reducing CO₂ emissions and deploying scalable climate solu...

• Climate / Energy
• Other

• Seed
• $500K – $4.0M
• Boston, MA
• 1 portfolio company

Investing in transformative solutions that drive sustainable progress and address climate change.

• Climate / Energy

• Seed, Series A
• $750K – $5.0M
• San Francisco, CA
• 1 portfolio company

Focus on transformative seed-stage Climate Tech solutions with scalable SaaS models.

• Climate / Energy

• Seed
• $1.0M – $3.0M
• San Francisco, CA
• 2 portfolio companies

Investing in technology-driven solutions to accelerate the clean energy transition and reduce carbon footprint.

• Climate / Energy

• Seed
• $1.0M – $3.0M
• Denver, CO
• 1 portfolio company

Focused on investment in CleanTech and sustainable transportation solutions with a global impact.

• Climate / Energy
• Other

• Seed
• $1.0M – $5.0M
• Berlin, Germany

Investing in innovative CleanTech and PropTech solutions that address climate and energy efficiency challenges.

• Climate / Energy
• Real Estate
• SaaS

• Seed
• $500K – $3.0M
• 3 portfolio companies

Invests in pioneering solutions in clean energy focused on resource efficiency and sustainable practices.

• Climate / Energy
• Other
• AI / ML

• Pre-Seed, Seed, Series A
• $400K – $1.2M
• Oslo, Norway
• 4 portfolio companies

Clear invests early in frontier technology and services, including AI, IT infrastructure, enterprise software, semiconductors, and information security. It provides seed capital and hands-on company-b...

• SaaS
• Enterprise

• Pre-Seed, Seed
• $100K – $5.0M
• Palo Alto, United States
• 15 portfolio companies

Focuses on backing platforms with a strong marketplace dynamic and fintech overlap, particularly at pre-seed and seed stages.

• Marketplace
• Fintech

• Pre-Seed, Seed
• $300K – $2.0M
• Boston, MA
• 1 portfolio company

Focuses on investments in transportation, IoT, and logistics technologies that enhance energy efficiency and compliance.

• Other

• Seed, Series A
• $500K – $5.0M
• San Francisco, CA
• 1 portfolio company

ClearSky focuses on cutting-edge innovations in defense and supply chain solutions to address key global technology challenges.

• Other
• AI / ML

• Seed
• $750K – $2.0M
• Palm Beach, FL

ClearSky invests in cybersecurity companies addressing critical challenges in identity and access management for enterprise clients.

• Security
• Other
• Enterprise

• Seed
• $500K – $5.0M
• Palm Beach Gardens, FL
• 1 portfolio company

Deploys capital into scalable B2B SaaS solutions addressing inefficiencies in healthcare systems with a focus on clinical IT.

• Healthcare
• Other
• SaaS

• Pre-Seed, Seed
• $200K – $1.0M
• Philadelphia, PA
• 12 portfolio companies

Backing tech innovators advancing the commerce and digital retail ecosystems with AI.

• Other
• AI / ML
• Consumer

• Pre-Seed, Seed
• $200K – $1.0M
• New York, NY
• 1 portfolio company

Investing in clever approaches applying AI to consumer technology, aiming to enhance engagement and drive adoption on a global scale.

• Consumer
• AI / ML
• Fintech

• Pre-Seed, Seed
• $400K – $3.0M
• Charlotte, NC
• 6 portfolio companies

Focused exclusively on early-stage climate innovation, including methane reduction and digital carbon ecosystems.

• Other
• Climate / Energy

• Seed
• $750K – $4.0M
• Austin, TX
• 2 portfolio companies