BU

Buff Gold Ventures — VC Firm

Profile updated November 2026Website

Buff Gold Ventures is a venture capital firm. The firm has 16 portfolio companies in our records.

Portfolio
16 companies on record
Partners
3 listed
Check size
Not in our records
AUM
Not in our records

Last verified: 2026-08-29

Portfolio

16+ companies

Team

3 partners

About Buff Gold Ventures

Buff Gold Ventures is an investor firm with a focus on deep tech. The firm invests in university spin-outs and early-stage companies, particularly in areas such as AI, semiconductors, biotech, quantum technologies, drug discovery, climate change, and hardware-enabled data companies.

The team consists of Mark T. Lupa, General Partner, with a focus on deep tech, University of Colorado Boulder spin-outs, AI, semiconductors, and biotech; Tasso von Windheim, Associate, specializing in deep tech commercialization and science and engineering spin-outs; and Sally Hatcher, General Partner, whose areas include deep tech, quantum technologies, drug discovery, climate change, and early-stage hardware-enabled data companies.

How Buff Gold Ventures invests

Buff Gold Ventures is a venture capital firm.

Buff Gold Ventures has backed 16 companies in our records, including POLARIS ELECTRO-OPTICS, LongPath Technologies, SinusLogic™.

Partners & Team

MT

Mark T. Lupa

General Partner

Deep Tech
University of Colorado Boulder spin-outs
AI
Semiconductors
Biotech
Climate Tech
TV

Tasso von Windheim

Associate

Deep Tech Commercialization
Science & Engineering spin-outs
SH

Sally Hatcher

General Partner

Deep Tech
Quantum Technologies
Drug Discovery
Climate Change
Early-stage Hardware-enabled Data Companies

Recent Activity

Investment Track Record

Buff Gold Ventures has recorded investments in 16 portfolio companies. These include Boco Bio, Codebreaker, Codebreaker Labs, Great Sky, LongPath Technologies, Mana Battery, Manifest, Manifest (Vitro3D), POLARIS ELECTRO-OPTICS, SinusLogic, Swept.ai, Think Bioscience, Tynt Technologies, and VitriVax. The firm has also recorded an investment in BUFF VENTURE FUND I, L.P.

Several of the recorded investments are at the seed stage. Great Sky operates in AI hardware, semiconductors, and deep-tech computing. Manifest (Vitro3D) is in advanced manufacturing, 3D printing, and machinery. Codebreaker Labs is also noted at the seed stage.

Portfolio Companies (16)

Other

PO

POLARIS ELECTRO-OPTICS

Buff Venture Fund I

Develops ferroelectric nematic liquid crystals and device reference designs for CMOS foundries to enhance electro‑optic modulators.

LO

LongPath Technologies

Buff Venture Fund I

Installs laser/sensor networks to provide low‑cost detection and quantification of methane and other gas emissions across large areas.

SI

SinusLogic™

Buff Venture Fund I

Develops medical technology and devices to treat chronic rhinosinusitis and sinus disease.

VI

VitriVax

Buff Venture Fund I

Biotech company with a novel stabilization and delivery platform for thermostable multi‑dose vaccines in a single shot.

TY

Tynt Technologies

Buff Venture Fund I

Develops dynamic tinting windows using Reverse Metal Electrodeposition technology to control solar glare and passive heat.

TH

Think Bioscience

Buff Venture Fund I

Uses genetically programmed microbial systems to discover and develop small‑molecule therapeutics for hard‑to‑drug targets.

MA

Manifest

VY

Vycarb

Buff Venture Fund I

Combines a novel carbon neutralization process with proprietary carbon sensing technology for instant, permanent, measurable CO₂ capture and storage in water.

CO

Codebreaker

Buff Venture Fund I

Builds genomic AI by programming biology to analyze and manipulate genomic data for superior insights.

MA

Mana Battery

Buff Venture Fund I

Develops high‑efficiency sodium battery technology.

How to pitch Buff Gold Ventures
  • •Address your outreach to a specific partner, such as Mark T. Lupa, General Partner.
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