AP

Aperture Venture Partners

VC
Denver, COWebsite

Aperture Venture Partners is a Pre-Seed, Seed venture capital firm based in Denver, CO investing in SaaS, Other, AI / ML. The firm typically writes $500K–$3.0M checks and has 10 portfolio companies in our records.

Check size
$500K–$3.0M
Portfolio
10 companies on record
Partners
6 listed
AUM
$101M
Stage
Pre-Seed, Seed
Sectors
SaaS, Other, AI / ML, Enterprise
HQ
Denver, CO

Last verified: 2026-06-16

How to approach: cold outreach ok
Stage

Pre-Seed, Seed

Check Size

$500K – $3.0M

AUM

$101M

Portfolio

10+ companies

Team

6 partners

Investor activity
Investments in last 12 months: 0

Investment Thesis

Focused on applied AI within B2B SaaS applications, particularly in sectors like hospitality and customer personalization.

How Aperture Venture Partners invests

Aperture Venture Partners is a vc firm based in Denver, CO. The firm invests at the Pre-Seed, Seed stages, with a focus on SaaS, Other, AI / ML, Enterprise.

Aperture Venture Partners typically writes checks of $500K–$3.0M per investment, backed by approximately $101M in assets under management.

Aperture Venture Partners has backed 10 companies in our records, including InsightsNow, WelcomeOS, Payment Labs.

Partners & Team

TN

Tony Natale, M.D.

Managing Partner

medical technologies
orthopedics
ENT
ophthalmology
GI
women’s health
A(

Anthony (Tony) Natale, M.D.

Managing Partner

medical device
minimally invasive technologies
women’s health
ophthalmology
ENT
GI
EH

Eric H. Sillman

General Partner

medical device
diagnostics
healthcare IT/services
pharmaceuticals
TP

Thomas P. Cooper, M.D.

Partner

healthcare operations
emergency medicine
correctional facility healthcare
service delivery in nursing homes
scaling healthcare companies
PE

Paul E. Tierney, Jr.

Managing Partner

pharmaceuticals
medical device
healthcare IT/services
capital raising, M&A, corporate governance
MY

Mark Yates

General Partner

B2B SaaS
Hospitality Tech

Industry Focus

Invests In

SaaS
Other
AI / ML
Enterprise

Portfolio Companies (10)

Other

IN

InsightsNow

AI Personalization
WE

WelcomeOS

Hospitality Tech
PA

Payment Labs

AN

Anonybit

SC

Scamnetic

PR

Pryon

MO

MOGL

AL

Alaffia

BR

BronX Medical Inc. (CIK 0001820098)

SEC Form D filing mentioning Aperture Venture Partners

SE

Serpex Medical Inc. (CIK 0001820098)

SEC Form D filing mentioning Aperture Venture Partners

How to pitch Aperture Venture Partners
  • Raising at Pre-Seed, Seed? You're squarely in their sweet spot.
  • Lead with your fit in SaaS, Other, AI / ML — the sectors they actively back.
  • Size your ask to their typical $500K – $3.0M check.
  • cold outreach ok
  • Address your outreach to a specific partner, such as Tony Natale, M.D., Managing Partner.
  • A warm introduction beats a cold email. Get matched and request an intro.

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