Pre-Seed AI & Machine Learning Venture Capital Firms

Firebolt says it partners with founders early and backs them through every stage; its public site does not specify a narrower current sector thesis.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $1.0M
• Palo Alto, California, United States
• 2 portfolio companies

Focuses exclusively on developer-first tools, AI-powered infrastructure, and SaaS solutions that enhance software productivity and engineering workflows.

• Developer Tools
• SaaS
• Other

• Pre-Seed, Seed
• $250K – $2.0M
• Austin, TX
• 2 portfolio companies

Firestarter VC focuses on early-stage B2B SaaS and AI startups that are at the forefront of technology innovation.

• SaaS
• Other
• Consumer

• Pre-Seed, Seed
• London, UK
• 18 portfolio companies

Emerging manager backing technical founders in infrastructure, AI, and software tools. Known for early conviction in products that can become core workflows for engineering teams.

• Developer Tools
• AI / ML
• Security

• Pre-Seed, Seed
• $100K – $1.5M
• New York, NY
• 6 portfolio companies

Invests in pioneering cybersecurity startups that target B2B SaaS for enterprise protection.

• Security
• SaaS
• Developer Tools

• Pre-Seed
• $500K – $2.0M
• San Francisco, CA
• 5 portfolio companies

Focused exclusively on seed-stage AI-powered startups in video streaming, media, and consumer digital sectors.

• AI / ML
• Other
• Healthcare

• Pre-Seed
• $100K – $300K
• San Francisco, CA
• 10 portfolio companies

Backs pre-seed startups in India solving complex enterprise AI and SaaS challenges.

• SaaS
• Other
• AI / ML

• Pre-Seed
• $100K – $750K
• Mumbai, India
• 87 portfolio companies

Seed-focused Canadian fund backing technical enterprise software and data/AI startups.

• Enterprise
• AI / ML
• SaaS

• Pre-Seed, Seed
• Toronto, Canada

Supports companies bringing transformational technologies to national defense and security sectors.

• Other
• Security
• Healthcare

• Pre-Seed, Seed
• $100K – $2.0M
• Washington, DC
• 49 portfolio companies

First Momentum backs European pre-seed deep-tech startups led by ambitious technical teams solving hard problems, across areas including climate and energy, compute, manufacturing and robotics, AI, ae...

• AI / ML
• SaaS
• Other

• Pre-Seed, Seed
• $285K – $1.7M
• Karlsruhe, Germany
• 40 portfolio companies

Focused on investing in technical founders solving hard engineering problems, with a preference for data, DevOps, and backend infrastructure.

• Developer Tools
• AI / ML

• Pre-Seed, Seed
• $250K – $2.5M
• Austin, TX
• 2 portfolio companies

Investing in automation-driven startups in underrepresented geographies with expertise in robotics and SaaS innovation.

• Other
• SaaS
• Enterprise

• Pre-Seed, Seed
• $200K – $3.0M
• Austin, TX
• 21 portfolio companies

First Star backs visionary, research-driven founders inventing a better future by riding new computing waves — from robotics and spatial intelligence to computational biology and AI — focusing on foun...

• Other
• AI / ML

• Pre-Seed, Seed
• $500K – $1.0M
• Cambridge, Massachusetts, United States
• 13 portfolio companies

Focuses on emerging B2B SaaS startups leveraging AI/ML and data to streamline enterprise workflows.

• SaaS
• Enterprise
• Other

• Pre-Seed, Seed
• $250K – $2.0M
• Austin, TX
• 13 portfolio companies

FirstVet Ventures is a specialized pet health-tech fund focused on telemedicine, predictive care, and pet wellness platforms.

• Other
• Healthcare
• AI / ML

• Pre-Seed, Seed
• $100K – $1.5M
• Stockholm, Sweden
• 8 portfolio companies

Invests at pre-seed and seed in European founders building global technology companies; it is sector-agnostic, with particular expertise in vertical AI applications and deep tech.

• AI / ML
• SaaS
• Other

• Pre-Seed, Seed
• $1.3M – $4.0M
• London, United Kingdom
• 9 portfolio companies

Dedicated to fashion tech and retail SaaS solutions that improve customer experiences and supply chain efficiency.

• Other
• AI / ML
• Consumer

• Pre-Seed, Seed
• $300K – $2.5M
• Boston, MA
• 8 portfolio companies

Early-stage investor with healthcare and IT exposure across African markets. A good fit for operational software that sits at the intersection of care delivery and technology.

• Healthcare
• Other
• Fintech

• Pre-Seed, Seed
• $100K – $4.9M
• 27 portfolio companies

Flagship builds and funds life sciences companies developing disruptive platforms in oncology, cell therapy, and synthetic biology.

• Healthcare
• AI / ML
• Other

• Pre-Seed, Seed, Series A
• $1.0M – $20.0M
• Cambridge, MA
• 8 portfolio companies

Fledge invests in companies solving real-world problems in energy, climate, and sustainable supply chains, with a particular interest in transportation-centric climate solutions.

• Climate / Energy
• Other
• AI / ML

• Seed, Pre-Seed
• $50K – $500K
• Seattle, WA
• 10 portfolio companies

SaaS Syndicate focuses on early-stage investments in enterprise SaaS startups delivering transformative productivity and AI solutions.

• SaaS
• Other
• AI / ML

• Seed, Pre-Seed
• $250K – $2.0M
• Remote (Global Syndicate)
• 2 portfolio companies

Flipside Ventures specializes in supporting blockchain infrastructure, crypto tools, and AI-powered B2B platforms.

• Other
• SaaS
• AI / ML

• Seed, Pre-Seed
• $250K – $2.0M
• Austin, TX
• 2 portfolio companies

Focuses on investments in enterprise software solutions that integrate AI to drive operational efficiencies in mid-sized businesses.

• Enterprise
• Other
• AI / ML

• Pre-Seed
• $500K – $1.5M
• Boston, MA
• 3 portfolio companies

Supports startups building tools that enhance developer productivity and operational efficiency, emphasizing AI-powered solutions.

• Developer Tools
• Other
• AI / ML

• Pre-Seed, Seed
• $200K – $2.0M
• Denver, CO
• 108 portfolio companies