Pre-Seed AI & Machine Learning Venture Capital Firms

Zetta Venture Partners invests in early-stage (pre-seed to Series A) AI-native B2B startups, especially those building applications, infrastructure, or developer tools in domains like biotech, securit...

• AI / ML
• SaaS

• Pre-Seed, Seed
• $1.0M – $5.0M
• San Francisco, California, USA
• 2 portfolio companies

Zillow Ventures invests in startups with the potential to disrupt real estate operations, transactions, and customer experience with innovative SaaS and AI solutions.

• Real Estate
• Other
• AI / ML

• Pre-Seed, Seed
• $200K – $1.0M
• Seattle, WA
• 16 portfolio companies

Zonal AI Ventures seeks to empower startups that utilize artificial intelligence to enhance B2B SaaS models in the PropTech sector.

• AI / ML
• SaaS
• Real Estate

• Pre-Seed
• $75K – $300K

Focused on real estate technologies that integrate AI to optimize zoning and land use planning.

• Real Estate
• AI / ML

• Pre-Seed
• $250K – $500K
• Seattle, WA

Large platform fund with dedicated enterprise/infrastructure focus; backs enterprise software companies from inception to scale.

• Enterprise
• SaaS
• Developer Tools

• Pre-Seed, Seed, Series A
• $500K – $5.0M
• Menlo Park, CA
• 10 portfolio companies

a16z invests across stages; pre-seed exposure often happens via scouts/angels and targeted seed programs.

• Other
• Security
• Consumer

• Pre-Seed
• $50K – $500K
• Menlo Park, CA
• 8 portfolio companies

Andreessen Horowitz's crypto arm invests in crypto and blockchain startups at all stages, with a focus on financial systems.

• Other
• Fintech
• Enterprise

• Pre-Seed, Seed
• $1.5M – $5.0M
• Menlo Park, USA
• 5 portfolio companies

Early-stage fund for technical founders building developer infrastructure.

• Developer Tools
• AI / ML

• Pre-Seed, Seed
• $100K – $1.0M
• US-SF

Investing in infrastructure AI and automation tools for developers and engineers.

• AI / ML
• Developer Tools
• Enterprise

• Pre-Seed, Seed
• $500K – $2.0M
• San Mateo, CA
• 2 portfolio companies

Emerging manager investing in Europe and the US, with activity across fintech, gaming, enterprise SaaS, and vertical AI. The firm is regionally differentiated and open to technical software companies.

• Other
• Enterprise
• AI / ML

• Pre-Seed, Seed
• 2 portfolio companies

An early-stage venture firm focusing on SaaS solutions tailored to government entities and services.

• Other
• SaaS
• AI / ML

• Pre-Seed, Seed
• $500K – $2.0M
• Washington, DC
• 12 portfolio companies

Participated in AI Diagnostics financing, indicating openness to early medtech and diagnostic technologies.

• Other
• Healthcare
• AI / ML

• Pre-Seed, Seed, Series A
• 8 portfolio companies

A pre-seed investor with deep tech and AI exposure that participated in a physical AI round. It can be relevant for highly technical infrastructure startups.

• AI / ML
• Deep Tech
• Other

• Pre-Seed, Seed
• San Francisco, CA
• 4 portfolio companies

Invest in pre-seed/seed founders in South & Southeast Asia building enterprise AI / fintech and regtech, with scalable architectures.

• Other
• Fintech
• Enterprise

• Pre-Seed, Seed
• $100K – $500K
• Singapore
• 10 portfolio companies

Specialist fund focused on startups transforming global supply chains with application and infrastructure software. The firm backs early-stage companies building logistics-focused platforms and relate...

• Other
• AI / ML
• Enterprise

• Pre-Seed, Seed
• $25K – $1.0M
• St. Louis, Missouri
• 19 portfolio companies