Pre-Seed AI & Machine Learning Venture Capital Firms

Invests in deep technology, new materials, AI applied to traditional industries, and medical devices, including technologies for early diagnosis.

• AI / ML
• SaaS

• Pre-Seed
• $200K – $1.0M
• Chicago, IL
• 1 portfolio company

A micro-fund targeting early-stage AI and SaaS platforms that aim to redefine industry paradigms.

• AI / ML
• SaaS

• Pre-Seed
• $200K – $1.0M
• Chicago, IL

Invests in early-stage companies transforming urban transportation and commuter experiences through scalable marketplace models.

• Other
• Marketplace
• Consumer

• Pre-Seed, Seed
• $200K – $1.5M
• Berlin, Germany
• 60 portfolio companies

Focused on tech that accelerates efficiency and innovation for brands selling through traditional and digital retail channels.

• Other
• Consumer
• Developer Tools

• Pre-Seed, Seed
• $500K – $2.0M
• New York, NY
• 1 portfolio company

Fintech seed specialist; only relevant if product is bundled/paid via HR benefits or linked to comp/retention ROI.

• Fintech
• Other
• SaaS

• Pre-Seed, Seed
• $250K – $2.0M
• San Francisco, CA
• 13 portfolio companies

Focused on funding companies driving measurable impact in climate resilience, sustainability, and equity-focused marketplaces.

• Other
• Marketplace
• Consumer

• Pre-Seed
• $500K – $2.0M
• Austin, TX
• 78 portfolio companies

Invests in scalable HealthTech ventures tailored for the Indian market.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $100K – $200K
• Chennai, India
• 1 portfolio company

BIV invests in technologies advancing alternative proteins, aquaculture, and food system sustainability.

• Food / AgTech
• Other
• AI / ML

• Pre-Seed, Seed
• $200K – $3.0M
• New York, USA
• 2 portfolio companies

Investing in innovations at the intersection of AI and biotechnology that promise to enhance health diagnostics and treatment protocols.

• AI / ML
• Other
• Healthcare

• Pre-Seed
• $600K – $1.8M
• Chicago, IL
• 5 portfolio companies

Invests in cutting-edge biotech and AI platforms that are transforming industries through integrative technology.

• Healthcare
• AI / ML
• Other

• Pre-Seed
• $1.0M – $12.0M
• Boston, MA
• 4 portfolio companies

Healthcare and HealthTech-focused fund investing at pre-seed and seed stages in transformational companies, particularly impactful solutions for multi-practitioner practices.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $500K – $3.0M
• Cambridge, MA
• 14 portfolio companies

Focuses on early-stage companies with technology for biodiversity impact and sustainable practices.

• SaaS
• Food / AgTech
• AI / ML

• Pre-Seed
• $500K – $2.5M
• San Francisco, CA
• 1 portfolio company

Biolumina Ventures focuses on early-stage biotech startups that are leveraging cutting-edge AI and data analytics to transform drug discovery processes.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $500K – $3.0M
• Austin, TX
• 6 portfolio companies

Focused on innovations in renewable biomanufacturing technologies and sustainable health solutions.

• Climate / Energy
• Healthcare
• Other

• Pre-Seed, Seed
• $250K – $1.0M
• San Francisco, CA
• 1 portfolio company

Focused exclusively on blockchain, crypto, and decentralized finance projects.

• Other
• AI / ML

• Pre-Seed, Seed
• $50K – $250K
• Berlin, Germany
• 2 portfolio companies

A pan-African angel syndicate investing in innovative tech companies solving socio-economic challenges.

• AI / ML
• Other
• EdTech

• Pre-Seed, Seed
• $10K – $300K
• Johannesburg, South Africa
• 2 portfolio companies

Backing Australian founders scaling technology-driven solutions in health and fitness with strong consumer appeal.

• Healthcare
• AI / ML
• Other

• Pre-Seed, Seed
• $500K – $5.0M
• Sydney, Australia
• 1 portfolio company

Blenheim Chalcot focuses on leveraging technology to enhance digital businesses in B2B SaaS and supporting infrastructure.

• SaaS
• Other
• Fintech

• Pre-Seed
• $250K – $1.0M
• London, UK
• 20 portfolio companies

Early-stage firm backing software startups with strong technical differentiation and product-led growth potential. A plausible fit for AI-enabled workflow software in commerce operations.

• SaaS
• Other
• AI / ML

• Pre-Seed, Seed
• 15 portfolio companies

BlockBase Ventures targets disruptive blockchain startups enhancing financial and telecom frameworks in Africa.

• Other
• Fintech
• AI / ML

• Pre-Seed, Seed
• $250K – $1.0M
• Nairobi, Kenya
• 2 portfolio companies

A micro-fund focused solely on RegTech innovations that leverage blockchain for compliance and efficiency.

• Other
• Food / AgTech
• Consumer

• Pre-Seed, Seed
• $200K – $1.0M
• Dublin, Ireland
• 7 portfolio companies

Focuses on blockchain and AI innovations enhancing governmental processes and public sector efficiency.

• Other
• AI / ML

• Pre-Seed
• $100K – $500K
• Austin, TX
• 1 portfolio company

Digital asset investor with broad interest in crypto finance, onchain markets, and protocol-level infrastructure. Strong relevance for B2B financial products built on blockchains.

• Other
• Fintech
• AI / ML

• Pre-Seed
• $500K – $3.0M
• New York, New York
• 26 portfolio companies

Dedicated to investments in the intersection of blockchain technology and interactive entertainment.

• Other
• AI / ML

• Pre-Seed
• $750K – $2.5M
• Austin, TX
• 1 portfolio company