Series A AI & Machine Learning Venture Capital Firms

Browse 579 venture capital firms that invest in AI & Machine Learning startups at the Series A stage. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified Series A AI & Machine Learning VC firms

Seismic Capital

Invests in marketplaces and SaaS platforms leveraging blockchain technologies to optimize workflows and marketplaces.

  • Marketplace
  • Other
  • SaaS
  • Seed, Series A
  • $500K – $3.0M
  • Chicago, IL
  • 11 portfolio companies

Seligman Ventures

Seligman Ventures appears in semiconductor AI funding activity, indicating interest in the space. It is a useful specialist/adjacent investor to approach for AI-native chip design infrastructure.

  • Other
  • AI / ML
  • Deep Tech
  • Seed, Series A

SensorEdge Ventures

Investing in edge solutions and IoT networks enabling efficiency and real-time oversight in industries such as cold chain logistics and supply chain management.

  • Other
  • AI / ML
  • Seed, Series A
  • $500K – $4.0M
  • Austin, TX
  • 1 portfolio company

Seraph Group

Invests in early-stage technology startups across high-growth sectors, using curated portfolios and co-investment. The firm does not publish a verifiable current range for typical initial check sizes.

  • Enterprise
  • SaaS
  • AI / ML
  • Seed+, Series A
  • $500K – $3.0M
  • Milton, Georgia, United States
  • 100 portfolio companies

Serena Ventures

Serena Ventures backs bold founders reshaping how we live, work, move, and connect, with a purpose to expand access, ownership, and opportunity at scale — especially supporting underrepresented founde...

  • SaaS
  • Developer Tools
  • AI / ML
  • Seed, Series A
  • $100K – $500K
  • San Francisco, California, United States
  • 5 portfolio companies

Serena Ventures

Seed and Series A investor with broad software and AI interest. Strong option for AI-driven SaaS with diverse founder profiles and market potential.

  • AI / ML
  • SaaS
  • Other
  • Seed, Series A
  • $500K – $5.0M
  • Los Angeles, California

Sfermion

Sfermion invests in web3 and crypto-native consumer applications with strong community and network characteristics. It is comfortable with products that blend marketplace mechanics, identity, and on-c...

  • Other
  • Consumer
  • AI / ML
  • Seed, Series A
  • $250K – $2.0M
  • New York, NY
  • 9 portfolio companies

Siana Capital

Siana Capital funds startups combining technology and financial services to innovate in healthcare, insurance, and claims processing in India.

  • Healthcare
  • Other
  • Fintech
  • Seed, Series A
  • $500K – $3.0M
  • Pune, India
  • 6 portfolio companies

Sift Ventures

Sift Ventures specializes in backing next-generation marketplaces and SaaS-driven platforms disrupting legacy industries.

  • Marketplace
  • SaaS
  • Consumer
  • Pre-Seed, Seed, Series A
  • $500K – $5.0M
  • San Francisco, CA
  • 2 portfolio companies

Sigma Prime Ventures

Focuses on innovative companies that leverage technology to transform their industries, with a strong interest in digital health innovations.

  • AI / ML
  • Healthcare
  • Enterprise
  • Seed, Series A
  • $1.0M – $5.0M
  • Boston, MA
  • 34 portfolio companies

Signal Horizon VC

Invests in early-stage startups leveraging AI and IoT solutions to disrupt industrial ecosystems with data-driven technologies.

  • Other
  • AI / ML
  • Developer Tools
  • Seed, Series A
  • $500K – $5.0M
  • Denver, CO
  • 1 portfolio company

Signal Ventures

Specializes in technology driving retail displays, signage, and sales enablement focused on physical store solutions.

  • Other
  • SaaS
  • AI / ML
  • Seed, Series A
  • $3.0M – $10.0M
  • New York, NY
  • 2 portfolio companies

SignalCraft Capital

SignalCraft Capital invests in AI-powered SaaS solutions transforming enterprise-level marketing and personalization.

  • AI / ML
  • SaaS
  • Other
  • Seed, Series A
  • $500K – $5.0M
  • San Francisco, CA
  • 2 portfolio companies

SignalFire Security Fund

SignalFire's dedicated security fund invests in AI-enabled cybersecurity startups improving compliance and protection in enterprise environments.

  • Security
  • AI / ML
  • Seed, Series A
  • $500K – $5.0M
  • San Francisco, CA
  • 2 portfolio companies

SilverAge Ventures

Specializes in investments in startups transforming senior care through technology innovations.

  • Other
  • Healthcare
  • AI / ML
  • $1.5M pre-seed, Seed, Series A
  • $500K – $4.0M
  • Minneapolis, MN
  • 1 portfolio company

Skybound Ventures

Focuses on storytelling-first companies creating innovative IP in television, video games, and digital entertainment.

  • Other
  • AI / ML
  • Seed, Series A
  • $500K – $5.0M
  • Los Angeles, CA
  • 2 portfolio companies

Smart Partnership Capital

  • SaaS
  • Other
  • Consumer
  • Pre-Seed, Pre-Seed+, Seed, Seed+, Series A
  • $100K – $1.5M

Smartlink

Investor participating in AI sports tracking and visualization rounds.

  • AI / ML
  • Other
  • Seed, Series A

Social Seed Fund

Invests in early-stage companies that leverage AI and analytics to drive new engagement strategies on social platforms.

  • Other
  • Developer Tools
  • AI / ML
  • Pre-Seed, Seed, Series A
  • $250K – $3.0M
  • Austin, TX
  • 1 portfolio company

SoftBank Vision Fund (AI Healthcare Team)

Focuses on transformative AI-driven innovations in B2B and healthcare verticals.

  • AI / ML
  • Enterprise
  • SaaS
  • Series A, Seed
  • $1.5M – $20.0M
  • Tokyo, Japan
  • 26 portfolio companies

Solstice Capital

Solstice Capital is dedicated to propelling cutting-edge AI and enterprise-level software solutions with transformative potential.

  • AI / ML
  • Enterprise
  • Seed, Series A
  • $1.0M – $3.0M
  • Portland, OR
  • 1 portfolio company

Soma Capital

Soma backs software-driven startups across crypto, fintech, and marketplace categories, often at early growth stages. The firm is comfortable with globally oriented infrastructure businesses and produ...

  • SaaS
  • Marketplace
  • Other
  • Pre-Seed, Seed, Series A
  • $250K – $1.0M
  • San Francisco, CA
  • 13 portfolio companies

Spark Capital

We believe in the founders who build the future.

  • Consumer
  • Enterprise
  • Fintech
  • Seed, Series A
  • $1.0M – $20.0M
  • US-SF
  • 30 portfolio companies

Spark Digital Capital

Specialist crypto firm investing in blockchain infrastructure, mass adoption technologies, and DeFi networks at early stages.

  • Other
  • Developer Tools
  • AI / ML
  • Pre-Seed, Seed, Series A
  • 8 portfolio companies

Showing 457–480 of 579 firms — page 20 of 25.

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