Pre-Seed AI & Machine Learning Venture Capital Firms

Browse 2,324 venture capital firms that invest in AI & Machine Learning startups at the Pre-Seed stage. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified Pre-Seed AI & Machine Learning VC firms

Samaipata

Samaipata focuses on digital platforms and tech ecosystems at their earliest stages, particularly in B2B SaaS and AI-powered marketplaces.

  • SaaS
  • Marketplace
  • AI / ML
  • Pre-Seed, Seed
  • $700K – $2.5M
  • Madrid, Spain
  • 43 portfolio companies

Sands Capital Ventures

Growth-oriented early-stage investor with a venture practice that backs enterprise software and select industrial technology companies.

  • Enterprise
  • Other
  • SaaS
  • Pre-Seed, Seed, Series A
  • $500K – $3.0M
  • Arlington, Virginia
  • 19 portfolio companies

Sapling Ventures

Focuses on early-stage technology startups transforming HR Tech and recruitment processes, prioritizing ML/AI-driven solutions for talent acquisition.

  • Other
  • AI / ML
  • SaaS
  • Pre-Seed, Seed
  • $500K – $1.5M
  • New York, NY
  • 2 portfolio companies

Sapphire Edge Ventures

Focused on AI/ML and enterprise SaaS applications, offering scalable infrastructure solutions.

  • AI / ML
  • SaaS
  • Enterprise
  • Pre-Seed
  • $500K – $3.0M
  • Austin, TX
  • 31 portfolio companies

Sapphire Technovations

Focused on investing in early-stage startups leveraging AI to solve healthcare operational inefficiencies.

  • Healthcare
  • SaaS
  • AI / ML
  • Pre-Seed
  • $750K – $3.0M
  • Austin, TX
  • 1 portfolio company

Sarah Smith Fund

AI-native solo GP fund; launched via rolling fund, then traditional Fund I; check size ≈ US$250K typically into early-stage with deep founder/market fit.

  • AI / ML
  • Fintech
  • Other
  • Pre-Seed, Seed
  • $250K+
  • USA (via AngelList)
  • 49 portfolio companies

Savanna Innovation Capital

Investing in Ghanaian fintech startups that bring digital transformation to traditional financial services.

  • Fintech
  • Other
  • Real Estate
  • Pre-Seed, Seed
  • $100K – $300K
  • Accra, Ghana
  • 27 portfolio companies

Savant

Participated in an AI Diagnostics round, implying some appetite for technical healthcare and diagnostic innovation.

  • Other
  • Security
  • Climate / Energy
  • Pre-Seed, Seed, Series A
  • 13 portfolio companies

Savia Ventures

Regional early-stage investor in Latin America with interest in technology-enabled consumer and marketplace businesses. Its geography and stage focus make it a fit for founders building local consumer...

  • Marketplace
  • Consumer
  • Food / AgTech
  • Pre-Seed, Seed
  • Santiago, Chile
  • 17 portfolio companies

ScOp Venture Capital

ScOp backs technical B2B software and deep-tech startups, with recent visibility in AI semiconductor design and verification through ChipAgents. The firm is a strong fit for pre-seed infrastructure so...

  • AI / ML
  • Other
  • SaaS
  • Pre-Seed, Seed, Series A
  • $250K – $2.0M
  • Santa Barbara, California
  • 40 portfolio companies

Scala Innovations

Scala Innovations is dedicated to empowering tech-driven startups utilizing AI to create efficiency across operations and management.

  • AI / ML
  • Enterprise
  • SaaS
  • Pre-Seed
  • $100K – $1.0M
  • Austin, TX
  • 5 portfolio companies

ScaleLane Ventures

Focuses exclusively on AI-driven productivity tools and enterprise SaaS solutions.

  • SaaS
  • Other
  • AI / ML
  • Pre-Seed
  • $1.0M – $3.0M
  • New York, NY
  • 1 portfolio company

ScaleScope Ventures

Focuses on scalable B2B SaaS and marketplace startups solving efficiency problems across industries.

  • SaaS
  • Marketplace
  • Enterprise
  • Seed, Pre-Seed
  • $1.0M – $3.0M
  • Austin, TX
  • 35 portfolio companies

ScaleStar Ventures

Focused on early-stage companies leveraging AI and automation tools to drive efficiencies in sales and marketing processes.

  • Other
  • SaaS
  • AI / ML
  • Seed, Pre-Seed
  • $250K – $1.5M
  • Denver, CO
  • 1 portfolio company

ScaleUp Health

Focuses on startups driving innovations in preventive health and wellness, leveraging AI for better client management.

  • Healthcare
  • AI / ML
  • Pre-Seed, Seed
  • $100K – $2.5M
  • Chicago, IL

ScaleX Ventures

Focuses exclusively on startups leveraging AI and automation to reimagine Sales Tech and revenue operations for SMBs and mid-market businesses.

  • Other
  • SaaS
  • AI / ML
  • Seed, Pre-Seed
  • $250K – $5.0M
  • Austin, TX
  • 31 portfolio companies

Scaled AI

Scaled AI invests in early-stage startups leveraging cutting-edge AI to transform operations safely and effectively.

  • AI / ML
  • Other
  • SaaS
  • Pre-Seed, Seed
  • $500K – $5.0M
  • San Francisco, CA
  • 2 portfolio companies

Scarlet Ventures

Invests in HealthTech startups that innovate patient care systems using AI and tech-driven solutions.

  • Healthcare
  • Other
  • Consumer
  • Pre-Seed
  • $50K – $250K
  • Boston, MA
  • 4 portfolio companies

Scene Ventures

Dedicated to funding technologies that transform how entertainment content is produced and consumed, with a strong focus on sustainable models.

  • Other
  • SaaS
  • AI / ML
  • Pre-Seed
  • $250K – $2.0M
  • Los Angeles, CA
  • 3 portfolio companies

Schema Ventures

Solo-GP fund launched to back ambitious early-stage startups, with a founder-led investment style and likely emphasis on software, AI, and application-layer products. A good fit for highly differentia...

  • AI / ML
  • Other
  • SaaS
  • Pre-Seed, Seed
  • 13 portfolio companies

Scholastic Ventures

Committed to investing in education technology that offers smart solutions to the traditional learning pain points, particularly in exam-oriented products.

  • EdTech
  • Other
  • Consumer
  • Seed, Pre-Seed
  • $300K – $2.0M
  • London, UK
  • 7 portfolio companies

Science Fair Fund

Very small pre-seed fund focused on AI, software, and deep tech founders. Best for technical products with a strong product and research edge.

  • AI / ML
  • Other
  • Deep Tech
  • Pre-Seed
  • US
  • 64 portfolio companies

Scopus Ventures

Backing founders leveraging AI-driven technologies for sales and marketing automation, with a focus on B2B SaaS.

  • AI / ML
  • SaaS
  • Other
  • Seed, Pre-Seed
  • $50K – $1.0M
  • Los Angeles, CA
  • 17 portfolio companies

Scoutly Ventures

Focusing exclusively on guiding early-stage startups in the e-commerce and analytics domains towards scalable success.

  • Other
  • SaaS
  • Consumer
  • Pre-Seed
  • $50K – $250K
  • Austin, TX
  • 11 portfolio companies

Showing 1849–1872 of 2324 firms — page 78 of 97.

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