Pre-Seed AI & Machine Learning Venture Capital Firms

Investing in AI-powered healthcare startups, particularly those addressing bottlenecks in pharma sales and workflows.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $100K – $400K
• Los Angeles, CA
• 2 portfolio companies

Focuses on consumer apps that improve personal health and wellness through AI and digital innovation.

• Healthcare
• Other
• Consumer

• Pre-Seed, Seed
• $50K – $150K
• Chicago, IL
• 1 portfolio company

Focuses on early-stage investments in technology-driven oil & gas and industrial supply chain startups, especially those modernizing procurement processes.

• Other
• SaaS
• Enterprise

• Pre-Seed
• $1.0M – $3.0M
• Houston, TX
• 6 portfolio companies

Focused on transformative HealthTech and PharmaTech startups that utilize AI for operational efficiencies.

• Healthcare
• Other
• SaaS

• Pre-Seed, Seed
• $100K – $1.0M
• Boston, MA
• 5 portfolio companies

Focused solely on startups that revolutionize pharmaceutical supply chains and networks using tech.

• Other
• Healthcare
• AI / ML

• Pre-Seed, Seed
• $100K – $1.2M
• San Diego, CA
• 5 portfolio companies

Backing startups revolutionizing pharmaceutical workflows, sales, and supply chains with tech-driven solutions.

• Other
• Healthcare
• SaaS

• Seed, Pre-Seed
• $100K – $500K
• London, UK
• 2 portfolio companies

Investing in startups revolutionizing environmental due diligence workflows through AI-driven innovation.

• Other
• Real Estate
• AI / ML

• Pre-Seed, Seed
• $1.0M – $4.0M
• Boston, MA
• 1 portfolio company

PhaseShift Capital targets disruptive B2B AI software startups in underserved geographies. Their thesis emphasizes AI for lead generation, customer success, and automated workflows.

• AI / ML
• SaaS
• Enterprise

• Pre-Seed, Seed
• $200K – $1.0M
• Chicago, IL
• 10 portfolio companies

Invests in early-stage companies innovating in AI and consumer software, with a preference for seamless integrations.

• AI / ML
• Consumer
• EdTech

• Pre-Seed
• $250K – $1.3M
• Boston, MA
• 9 portfolio companies

Early-stage proptech venture firm focused on technology for real estate and the built environment. Invests in software and services that digitize property operations.

• Real Estate
• SaaS
• AI / ML

• Pre-Seed, Seed
• $100K – $1.0M
• London, United Kingdom
• 8 portfolio companies

pi Ventures invests in early-stage deep-tech companies in areas like AI/ML, robotics, quantum computing, advanced materials, energy & life sciences, backing founders building disruptive tech with stro...

• AI / ML
• SaaS
• Deep Tech

• Pre-Seed, Seed
• $250K – $3.0M
• Bengaluru, India
• 1 portfolio company

Pi Ventures targets AI-driven startups in the fintech space aiming to improve financial operations and automation.

• AI / ML
• Fintech
• Other

• Pre-Seed, Seed
• $100K – $500K
• 3 portfolio companies

Piccolo Ventures invests in cutting-edge enterprise AI and automation startups that reduce the complexity in legacy systems and unlock scalable workflows.

• Other
• SaaS
• Enterprise

• Pre-Seed, Seed
• $1.0M – $4.0M
• Austin, TX
• 105 portfolio companies

Early-stage software and fintech investor with broad European reach. Good fit for an ambitious AI-enabled SMB financial operating system with international expansion potential.

• Fintech
• SaaS
• AI / ML

• Pre-Seed, Seed
• $250K – $2.0M
• Munich, Germany
• 12 portfolio companies

Supports AI-powered startups transforming finance, analytics, and operations in the B2B space.

• AI / ML
• SaaS
• Developer Tools

• Pre-Seed, Seed
• $500K – $2.5M
• New York, NY
• 2 portfolio companies

Targets Security Tech and GovTech innovations, leveraging technology to build resilient infrastructures and secure solutions for global challenges.

• Other
• Consumer
• SaaS

• Pre-Seed, Seed
• $250K – $1.2M
• Boston, MA
• 19 portfolio companies

Invests in B2B Software solutions using AI to optimize investment strategies.

• AI / ML
• Fintech

• Pre-Seed
• $1.0M – $4.0M
• Austin, TX

Pre-seed and seed investor backing founders across fintech, logistics technology, healthtech, and retail, with a deliberate geographic concentration on Europe.

• Other
• Fintech
• Healthcare

• Pre-Seed, Seed
• $100K – $500K
• Madrid, Spain
• 16 portfolio companies

Invests in early and very early-stage AI startups in the Nordics, including companies pioneering AI or applying it innovatively in traditional sectors; the firm also cites ESG impact, team, market opp...

• AI / ML
• SaaS

• Pre-Seed
• $150K – $150K
• Frederiksberg, Denmark

Pioneer AI Syndicate focuses on early-stage AI software that streamlines business processes.

• Other
• SaaS
• AI / ML

• Pre-Seed, Seed
• $100K – $1.5M
• Toronto, Canada
• 2 portfolio companies

Focuses exclusively on field service management software for small businesses, supporting SaaS solutions that streamline operations.

• SaaS
• Other
• Healthcare

• Pre-Seed, Seed
• $50K – $250K
• Portland, OR
• 4 portfolio companies

Focused exclusively on emerging technologies that improve clinical workflows and patient outcomes in outpatient settings.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $2.0M
• Boston, MA
• 1 portfolio company

Focused on impactful AI and RetailTech that redefine traditional business models.

• AI / ML
• Other

• Pre-Seed
• $250K – $1.0M
• London, UK

Invests in frontier technologies redefining audio production and AI-powered workflows in music creation.

• Other
• AI / ML
• EdTech

• Pre-Seed, Seed
• $50K – $400K
• Austin, TX
• 37 portfolio companies