Venture Capital Firms in Chicago

Browse 717 venture capital firms headquartered in Chicago. Median check across the 708 firms that disclose a range is $500K–$2.5M; most active at Seed, Pre-Seed, Series A; concentrated in SaaS, AI / ML, Enterprise. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified Chicago VC firms

POS Ventures

Aims to invest in startups modernizing point-of-sale systems and streamlining the backend for retailers and restaurants.

  • Other
  • Pre-Seed, Seed, Series A
  • $250K – $2.0M
  • Chicago, IL
  • 2 portfolio companies

Pinnacle Software Fund

Pinnacle Software Fund invests exclusively in B2B SaaS, focusing on vertical-specific platforms that transform niche industries.

  • SaaS
  • Seed
  • $750K – $3.0M
  • Chicago, IL
  • 2 portfolio companies

Pioneer One Ventures

A sector-agnostic micro fund emphasizing deep data platforms and SaaS applications bringing new paradigms in healthcare and enterprise tech.

  • SaaS
  • Healthcare
  • Other
  • Pre-Seed
  • $100K – $1.0M
  • Chicago, IL
  • 27 portfolio companies

Pioneer Seed Fund

Invests in new consumer technologies with a strong subscription model emphasis.

  • Consumer
  • Other
  • Seed
  • $250K – $1.5M
  • Chicago, IL
  • 1 portfolio company

Pioneering Media Fund

Empowers media-tech companies with innovative solutions to redefine the media landscape.

  • Other
  • Seed
  • $750K – $3.5M
  • Chicago, IL
  • 1 portfolio company

Piquant Capital

Investing in the convergence of Food Tech and Health to drive innovations that improve quality and access.

  • Food / AgTech
  • Healthcare
  • Consumer
  • Seed, Series A
  • $1.0M – $5.0M
  • Chicago, IL
  • 1 portfolio company

Pitstop Ventures

Investing in innovative startups at the intersection of automotive technology and AI to revolutionize car diagnostics.

  • Other
  • AI / ML
  • Pre-Seed, Seed
  • $250K – $2.0M
  • Chicago, Illinois

Placement Catalyst Fund

Specializes in early-stage companies disrupting the recruiting, hiring, and placement process for employers, with strong focus on software and automation for HR operations.

  • Other
  • SaaS
  • Seed, Series A
  • $500K – $3.5M
  • Chicago, IL
  • 2 portfolio companies

Plate Ventures

Plate Ventures focuses on B2B SaaS solutions in the Food Tech industry with the potential to scale rapidly.

  • Food / AgTech
  • SaaS
  • Seed
  • $1.5M – $3.0M
  • Chicago, IL
  • 1 portfolio company

Platform Ventures

Investing in marketplace models and B2B SaaS solutions that facilitate scalable and efficient business transactions.

  • Marketplace
  • SaaS
  • Consumer
  • Pre-Seed
  • $200K – $1.0M
  • Chicago, IL
  • 10 portfolio companies

Playbook Capital Partners

Focuses on early-stage SportsTech platforms enhancing operational and fan engagement tools for sports businesses.

  • Other
  • Consumer
  • Fintech
  • Pre-Seed, Seed
  • $750K – $5.0M
  • Chicago, IL, USA
  • 18 portfolio companies

Polymath Capital

Investing in the intersection of productivity technology and B2B SaaS tools that fuel operational excellence.

  • Other
  • SaaS
  • Enterprise
  • Pre-Seed, Seed
  • $100K – $1.0M
  • Chicago, IL
  • 37 portfolio companies

Portal Innovations

Portal Innovations invests in science-driven, early-stage life sciences, medtech, and bioinformatics startups—pre-seed through Series A—providing seed capital, lab space and operations expertise to co...

  • Healthcare
  • EdTech
  • Other
  • Pre-Seed, Seed
  • $500K – $3.0M
  • Chicago, Illinois, United States
  • 26 portfolio companies

Prairie Innovations Fund

The fund backs early-stage B2B SaaS startups, especially those enhancing supply chain efficiencies.

  • SaaS
  • Other
  • Pre-Seed, Seed
  • $800K – $2.5M
  • Chicago, IL

Praxis Real Estate Ventures

Praxis Real Estate Ventures focuses on innovative startups reshaping real estate investment landscapes through technology.

  • Other
  • Real Estate
  • Pre-Seed
  • $250K – $400K
  • Chicago, IL
  • 1 portfolio company

Pre-Sight Ventures

Pre-Sight focuses on backing the 'first check' aspirations of bold entrepreneurs.

  • Other
  • SaaS
  • Developer Tools
  • Pre-Seed
  • $100K – $400K
  • Chicago, IL
  • 1 portfolio company

Precision Compliance Capital

Dedicated to funding advancements in compliance and regulation through innovative software and AI solutions.

  • Other
  • AI / ML
  • Seed
  • $750K – $2.5M
  • Chicago, IL
  • 2 portfolio companies

Precision Cycle Partners

Focused on precision software solutions for life sciences, pharma, and healthcare industries, particularly compliant research workflows.

  • Healthcare
  • Other
  • SaaS
  • Seed, Series A
  • $100K – $300K
  • Chicago, IL
  • 2 portfolio companies

Precision DevEx Fund

Dedicated to investing in innovative DevOps and observability solutions that enhance system reliability and efficiency.

  • Developer Tools
  • Other
  • Pre-Seed
  • $100K – $250K
  • Chicago, IL
  • 1 portfolio company

Precision Edventures

Precision Edventures targets the evolution of educational technology solutions, focusing on scalable SaaS platforms with a strong B2B focus.

  • EdTech
  • SaaS
  • Enterprise
  • Pre-Seed
  • Chicago, IL
  • 1 portfolio company

Precision Engineering Ventures

Dedicated to early-stage investments in precision engineering and manufacturing technologies.

  • Other
  • Developer Tools
  • Seed
  • $1.0M – $3.0M
  • Chicago, IL
  • 3 portfolio companies

Prevention Venture Fund

Specializes in funding seed-stage companies that focus on preventive care innovations and consumer health applications.

  • Other
  • Healthcare
  • Seed
  • $150K – $500K
  • Chicago, IL

Prime Directive VC

Investing in the future of intelligent enterprise solutions that redefine productivity through AI platforms.

  • Other
  • Seed
  • $750K – $4.5M
  • Chicago, IL
  • 1 portfolio company

Pritzker Group Venture Capital

Established early-stage investor in software and enterprise technology. A reasonable fit for a scalable agency OS with strong commercial traction.

  • SaaS
  • Enterprise
  • AI / ML
  • Seed, Series A
  • $500K – $3.0M
  • Chicago, IL
  • 1 portfolio company

Showing 505–528 of 717 firms — page 22 of 30.

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