Venture Capital Firms in Chicago

Seed-stage digital health specialist focused on care delivery innovation and digital health infrastructure.

• Healthcare
• AI / ML
• EdTech

• Seed, Series A
• $250K – $1.5M
• Chicago, IL
• 35 portfolio companies

Focused on innovations in computer vision and fit personalization technologies for retailers and e-commerce brands.

• Other
• AI / ML
• Consumer

• Pre-Seed, Seed
• $250K – $3.0M
• Chicago, IL
• 2 portfolio companies

Invests in startups revolutionizing operational efficiency and supply chains.

• Other

• Pre-Seed, Seed
• $250K – $4.0M
• Chicago, IL
• 1 portfolio company

Backs B2B SaaS companies solving operational inefficiencies for SMB and enterprise customers.

• SaaS
• Other

• Seed
• $1.0M – $3.0M
• Chicago, IL
• 33 portfolio companies

Specializes in funding early-stage automation technologies that optimize business operations for mid-market enterprises.

• SaaS
• Other
• Enterprise

• Pre-Seed, Seed
• $500K – $2.5M
• Chicago, IL
• 23 portfolio companies

Specializes in AI-driven operational intelligence solutions targeting B2B startups serving the SMB market.

• Other

• Seed, Series A
• $1.0M – $5.0M
• Chicago, IL
• 1 portfolio company

Investing in cutting-edge optical and sensor technologies for industrial use.

• Other
• Healthcare

• Pre-Seed, Seed
• $500K – $3.0M
• Chicago, IL
• 8 portfolio companies

Focuses on scalable B2B SaaS solutions transforming restaurant operations and supporting independent operators with technological innovations.

• Other
• SaaS
• Food / AgTech

• Pre-Seed, Seed
• $500K – $3.0M
• Chicago, IL
• 2 portfolio companies

Focused on early-stage B2B SaaS and marketplace startups in underrepresented hubs including the Midwest.

• Marketplace
• SaaS

• Seed, Series A
• $500K – $4.0M
• Chicago, IL, USA
• 10 portfolio companies

Invests in early and growth-stage companies enabling enterprise sales teams to achieve higher effectiveness and scalability.

• Other
• SaaS

• Seed, Series A
• $1.0M – $5.0M
• Chicago, IL
• 1 portfolio company

Backing pre-seed companies building digital tools to streamline small restaurant and retail operations.

• Other
• SaaS
• Enterprise

• Pre-Seed, Seed
• $100K – $1.5M
• Chicago, IL
• 2 portfolio companies

Invests in automation-first startups transforming legacy enterprise infrastructure.

• Other
• SaaS
• Enterprise

• Seed
• $1.0M – $5.0M
• Chicago, IL
• 1 portfolio company

Invests in Midwest-based companies with a focus on scaling SaaS solutions for enterprise adoption.

• SaaS
• Enterprise

• Pre-Seed, Seed
• $200K – $1.5M
• Chicago, IL
• 1 portfolio company

Investing in startups that push the boundaries of how data can be leveraged through programmability, AI, and code-based solutions.

• Other
• Developer Tools
• AI / ML

• Seed, Pre-Seed
• $500K – $4.0M
• Chicago, IL
• 2 portfolio companies

Bets on B2B companies optimizing operational efficiency through intelligent automation and data-driven processes.

• SaaS
• AI / ML
• Other

• Seed, Series A
• $200K – $1.5M
• Chicago, IL
• 2 portfolio companies

Invests in high-growth pet product companies pioneering eco-friendly tools and B2C subscription ecosystems.

• Other

• Pre-Seed, Seed
• $250K – $1.0M
• Chicago, IL
• 1 portfolio company

Investing in transformative people operations and talent management software at the intersection of AI and HR.

• Other
• AI / ML

• Seed
• $150K – $1.0M
• Chicago, IL
• 1 portfolio company

Investing in technology to revolutionize the HR and people-ops sector with a focus on SaaS and wellbeing tools.

• Other
• SaaS
• Developer Tools

• Pre-Seed, Seed
• $500K – $3.0M
• Chicago, IL
• 8 portfolio companies

Perceptive Systems Ventures invests in cutting-edge AI software tailored to business intelligence and data insights for enterprises.

• Other
• SaaS

• Pre-Seed, Seed
• $150K – $1.0M
• Chicago, IL
• 2 portfolio companies

Investing in the next wave of business intelligence and enterprise AI to unlock actionable insights from data.

• Other
• Developer Tools
• AI / ML

• Seed, Series A
• $250K – $2.0M
• Chicago, IL
• 15 portfolio companies

Focuses on consumer apps that improve personal health and wellness through AI and digital innovation.

• Healthcare
• Other
• Consumer

• Pre-Seed, Seed
• $50K – $150K
• Chicago, IL
• 1 portfolio company

Focuses exclusively on early-stage technology companies in the pharmaceutical sector.

• Healthcare
• Other

• Seed
• $1.0M – $3.0M
• Chicago, IL
• 3 portfolio companies

Focuses exclusively on startups building pharmacy-specific SaaS applications for operational and insurance efficiency.

• Other
• SaaS

• Pre-Seed, Seed
• $300K – $1.0M
• Chicago, IL
• 1 portfolio company

PhaseShift Capital targets disruptive B2B AI software startups in underserved geographies. Their thesis emphasizes AI for lead generation, customer success, and automated workflows.

• AI / ML
• SaaS
• Enterprise

• Pre-Seed, Seed
• $200K – $1.0M
• Chicago, IL
• 10 portfolio companies