Series B Venture Capital Firms

Browse 83 venture capital firms that actively invest at the Series B stage. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified Series B VC firms

Transformation Capital

Focuses exclusively on healthcare technology companies that are reshaping healthcare delivery and operations.

  • Healthcare
  • SaaS
  • AI / ML
  • Series A, Series B
  • $5.0M – $20.0M
  • Boston, MA
  • 2 portfolio companies

Two Sigma Ventures

TSV invests in early-stage, data-driven startups—especially those where information, computation, AI/ML, and deep engineering lie at the core of the product—with a focus on Seed through Series A/B rou...

  • AI / ML
  • Developer Tools
  • Enterprise
  • Seed, Series A, Series B
  • $2.0M – $15.0M
  • New York City, New York, USA
  • 30 portfolio companies

VC23 Ventures

Biotools-focused fund backing companies that power modern biotech—from next-generation research tools to data and AI automation platforms, with a core focus on life-science tools and diagnostics.

  • Other
  • AI / ML
  • Developer Tools
  • Seed, Series A, Series B
  • 12 portfolio companies

Vibrant Ventures

A boutique fund committed to supporting emerging food & beverage companies including innovative restaurant concepts.

  • Food / AgTech
  • Other
  • Series A, Series B
  • $2.0M – $10.0M
  • Los Angeles, CA
  • 2 portfolio companies

Vitalize Ventures

Invests in early- to mid-stage SaaS startups modernizing the healthcare ecosystem, with interest in B2B solutions eliminating inefficiencies.

  • Healthcare
  • SaaS
  • Enterprise
  • Seed, Series A, Series B
  • $1.0M – $10.0M
  • Chicago, IL
  • 2 portfolio companies

Wavecrest Growth Partners

Wavecrest invests in capital-efficient software and marketplace businesses with clear revenue models and strong operational leverage. The firm is known for backing companies that combine software work...

  • Marketplace
  • SaaS
  • Fintech
  • Series A, Series B
  • $500K – $3.0M
  • Boston, MA
  • 7 portfolio companies

Waveform Capital

Invests in breakthroughs within media and advertising technology, with an emphasis on enterprise SaaS solutions for content creators.

  • Other
  • SaaS
  • Series A, Series B
  • $1.5M – $3.0M
  • Austin, TX
  • 2 portfolio companies

Wellington Partners

Pan-European life science and medtech investor backing clinically validated innovations with strong teams and commercialization pathways.

  • Other
  • Healthcare
  • EdTech
  • Series A, Series B
  • $1.0M – $10.0M
  • Munich, Germany
  • 14 portfolio companies

Wholestack

Backs emerging domain funds (Fund I-II) globally focused on fringe but foundational sectors including Alternative Proteins, Food Production, Synthetic Biology.

  • Other
  • AI / ML
  • Food / AgTech
  • Seed, Series A, Series B
  • 1 portfolio company

Wilshire Lane Capital

An early-stage venture firm dedicated to PropTech, with a debut fund focused on seed through Series B investments in real estate technology. The firm explicitly backs companies in the PropTech space.

  • Real Estate
  • Other
  • Seed, Series A, Series B
  • Los Angeles, California

World Innovation Lab (WiL)

WiL invests in growth-stage technology companies, especially B2B software/infrastructure, helping firms scale globally with a special emphasis on expansion into Japan and broader Asia, leveraging its ...

  • AI / ML
  • SaaS
  • EdTech
  • seed+, Series A, Series B
  • $10.0M – $50.0M
  • Palo Alto, California, United States
  • 11 portfolio companies

Showing 73–83 of 83 firms — page 4 of 4.

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