Series A Venture Capital Firms

Sector-specific fund focused on the intersection of tech and live events to empower SMB and enterprise event operators.

• Other
• SaaS

• seed+, Series A
• $3.0M – $7.0M
• San Francisco, CA
• 2 portfolio companies

Supports seed-stage and growth companies in B2B SaaS and AI innovation, with interest in enterprise data solutions and compliance-heavy workflows.

• SaaS
• Enterprise
• AI / ML

• Seed, Series A
• $1.0M – $8.0M
• Glasgow, UK
• 1 portfolio company

Healthcare and life sciences investor with interest in software, diagnostics, and healthcare technology. Strong across digital health and care delivery innovation.

• Healthcare
• Other

• Seed, Series A
• $1.0M – $5.0M
• San Francisco, California

Focuses on transformative Fintech and HealthTech companies building scalable, technology-led platforms.

• Fintech
• Healthcare

• Seed, Series A
• $1.0M – $3.0M
• Miami, FL
• 2 portfolio companies

Maveron focuses exclusively on consumer businesses, investing in early-stage companies that have the potential to redefine industries and create enduring brands.

• Consumer
• Other
• Healthcare

• Seed, Series A
• $1.0M – $10.0M
• Seattle, WA, USA
• 30 portfolio companies

Mayfield invests in early-stage AI founders, often from company inception, with a people-first approach. Its current public materials describe it as an early institutional investor for AI founders.

• AI / ML
• Enterprise
• SaaS

• Seed, Series A
• $1.0M – $20.0M
• Menlo Park, California, United States

Mechanism Capital supports projects innovating in decentralized finance, blockchain infrastructure, and crypto-native applications.

• Other

• Seed, Series A
• $1.0M – $4.0M
• Global
• 13 portfolio companies

MedAxis Fund focuses exclusively on HealthTech and InsurTech companies driving innovation in regulated markets globally.

• Healthcare
• Other

• Seed, Series A
• $750K – $2.5M
• London, UK
• 2 portfolio companies

MedVenture Partners invests in digital health and healthcare IT-focused companies that leverage technology to create scalable healthcare solutions.

• Healthcare
• Other

• Seed, Series A
• $750K – $3.0M
• Austin, TX

Dedicated to seed investments in the Media sector with a tech-driven approach.

• Other

• Seed, Series A
• $1.0M – $3.0M
• New York, NY
• 1 portfolio company

Menlo Ventures invests at every early-to-growth stage—pre-seed, seed, Series A/B and inflection—in AI, consumer, enterprise, healthcare and frontier technologies, backing founder-led teams seeking pro...

• Enterprise
• Consumer
• Healthcare

• Seed, Series A, Series B
• $100K – $30.0M
• Menlo Park, California, United States
• 10 portfolio companies

Impact-focused venture arm backing market-systems solutions in fragile and frontier markets across climate resilience, financial inclusion and agriculture.

• Climate / Energy
• Food / AgTech
• Other

• Seed, Series A
• Portland, Oregon
• 50 portfolio companies

Based in Lima, Bogotá, Medellín, and Miami, we will invest USD 20 million in pre-seed and seed stages, supporting the best founders in Latin America. We focus on solving key human challenges, driving...

• Pre-Seed, Seed, Series A, pre_seed
• $100K – $1.0M
• Miami, Bogotá, Medellín, Lima
• 1 portfolio company

Specializing in geographically unique consumer brands within the Midwest and New England regions.

• Other
• Food / AgTech

• Series A
• $1.5M – $5.0M
• Boston, MA
• 1 portfolio company

Software investor with strong enterprise and infrastructure orientation. Relevant when a startup is early but has clear path to major platform scale.

• Enterprise
• Developer Tools
• AI / ML

• Seed, Series A
• $500K – $5.0M
• Palo Alto, California
• 25 portfolio companies

Merus Capital backs enterprise software and cloud infrastructure startups, with a history of investing in products adopted by developers, IT teams, and technical operators.

• Developer Tools
• Enterprise
• AI / ML

• Seed, Series A
• $500K – $2.5M
• Palo Alto, CA
• 72 portfolio companies

Specializes in startups innovating in meshed AI systems for advanced cybersecurity solutions targeted at enterprise SOCs.

• Other
• Security
• SaaS

• Seed, Series A
• $500K – $4.0M
• Boston, MA
• 32 portfolio companies

Focuses on disruptive semiconductor startups and wireless/AI hardware innovations.

• Other
• Deep Tech

• Seed, Series A
• $1.0M – $3.0M
• Palo Alto, CA
• 7 portfolio companies

Strategically invests in B2B SaaS companies that utilize data analytics to provide scalable solutions for business operations and efficiency.

• SaaS
• Developer Tools

• Series A
• $1.0M – $4.0M
• Chicago, IL
• 1 portfolio company

Invests in high-impact startups advancing semiconductor fabrication processes and materials to enable scalable, next-gen technologies.

• Other

• Seed, Series A
• $750K – $5.0M
• Phoenix, AZ
• 1 portfolio company

Microsoft’s venture fund investing in enterprise software and infrastructure aligned with cloud and AI.

• Enterprise
• AI / ML
• Security

• Seed, Series A
• $500K – $5.0M
• San Francisco, CA
• 14 portfolio companies

MiddleGame specializes in investing in European fintech companies that are building innovative platforms for the banking and payments ecosystem.

• Fintech
• Other
• SaaS

• Seed, Series A
• $500K – $3.0M
• Luxembourg
• 2 portfolio companies

Targets startups in the Midwest U.S. specializing in automotive technologies and B2B SaaS solutions.

• Other
• SaaS
• Enterprise

• Pre-Seed, Seed, Series A
• $500K – $3.0M
• Chicago, IL
• 25 portfolio companies

Supports companies in the Midwest innovating with SaaS solutions tailored for regional markets.

• Other
• SaaS

• Seed, Series A
• $1.0M – $5.0M
• Minneapolis, MN
• 1 portfolio company