Series A AI & Machine Learning Venture Capital Firms

Bets on B2B companies optimizing operational efficiency through intelligent automation and data-driven processes.

• SaaS
• AI / ML
• Other

• Seed, Series A
• $200K – $1.5M
• Chicago, IL
• 2 portfolio companies

Invests in novel blockchain solutions with a focus on improving institutional and financial infrastructure.

• Other
• AI / ML
• Developer Tools

• Series A
• $1.0M – $20.0M
• San Francisco, CA
• 1 portfolio company

PayPal Ventures invests strategically in payments and commerce infrastructure. It is relevant for products improving card spend control, merchant authorization, and payment rails.

• Other
• Fintech
• AI / ML

• Seed, Series A
• $500K – $3.0M
• San Jose, California
• 6 portfolio companies

Dedicated to investing in scalable B2B SaaS and e-commerce ventures in Canada, with an emphasis on creating strong long-term partnerships.

• SaaS
• Other
• Enterprise

• Seed, Series A
• $1.0M – $3.0M
• Toronto, Canada
• 64 portfolio companies

Early-stage venture firm focused on cloud, software, and fintech infrastructure businesses with enterprise potential.

• SaaS
• Fintech
• Other

• Seed, Series A
• Salt Lake City, UT
• 18 portfolio companies

Focuses on advanced computer vision, AR systems, and AI tools for improving immersive user experiences in consumer and enterprise products.

• Other
• AI / ML
• Enterprise

• Seed, Series A
• $1.0M – $5.0M
• Toronto, Canada
• 2 portfolio companies

Investing in the next wave of business intelligence and enterprise AI to unlock actionable insights from data.

• Other
• Developer Tools
• AI / ML

• Seed, Series A
• $250K – $2.0M
• Chicago, IL
• 15 portfolio companies

Focuses on startups building innovative pharmacy supply chain solutions and healthcare software platforms serving emerging markets.

• Other
• Healthcare
• AI / ML

• Seed, Series A
• $200K – $2.5M
• New Delhi, India
• 6 portfolio companies

Invests in startups building AI-powered tools to optimize pharmaceutical manufacturing, research, and compliance workflows.

• Other
• Healthcare
• SaaS

• Seed, Series A
• $250K – $1.0M
• San Diego, CA
• 13 portfolio companies

Investing in next-generation hardware solutions for AI, semiconductor applications, and wireless technologies.

• Other
• AI / ML
• Developer Tools

• Seed, Series A
• $400K – $4.0M
• Cambridge, MA
• 26 portfolio companies

Backing startups tackling revenue operations inefficiencies for SMB and mid-market businesses.

• Enterprise
• AI / ML
• Other

• Seed, Series A
• $250K – $1.0M
• Austin, TX
• 1 portfolio company

Investing in technology innovations that revolutionize marketing strategies and B2B service delivery, with a preference for data-driven companies.

• Other
• SaaS
• AI / ML

• Seed, Series A
• $750K – $4.0M
• San Diego, CA
• 5 portfolio companies

PixelThread Capital invests in companies creating innovative software tools for direct-to-consumer fashion brands, elevating operational and marketing capabilities with AI.

• Other
• AI / ML

• Seed, Series A
• $500K – $3.0M
• Austin, TX
• 1 portfolio company

Invests in transformational companies using technology to address global environmental challenges, including AI-driven climate solutions.

• Climate / Energy
• AI / ML

• Seed, Series A
• $1.0M – $4.0M
• London, UK
• 1 portfolio company

Early-stage fund focused on creators and gaming platforms leveraging AI and social experiences. Supports startups that merge user-generated content with deep engagement mechanics.

• Other
• AI / ML

• Seed, Series A
• $1.0M – $10.0M
• Berlin, Germany
• 2 portfolio companies

Playground backs early-stage deep-tech founders working in next-generation compute, automation, energy transition, and engineered biology, including AI and hard-science companies.

• AI / ML
• Consumer
• Other

• Seed, Series A
• $1.0M – $20.0M
• Palo Alto, California, United States
• 2 portfolio companies

Point Break invests in data-rich fintech startups solving major pain points in payments and retail across Europe.

• Fintech
• Other
• AI / ML

• Seed, Series A
• $1.0M – $3.0M
• Barcelona, Spain
• 2 portfolio companies

Dedicated to supply chain innovation, investing in cold chain logistics and IoT technologies that drive efficiency, reduce costs, and enhance automation.

• Other
• AI / ML

• Seed, Series A
• $500K – $5.0M
• Seattle, WA
• 1 portfolio company

Invests in precision health technologies, aiming to transform healthcare delivery and efficiency.

• Healthcare
• Other
• SaaS

• Pre-Seed, Seed, Series A
• $400K – $2.5M
• Boston, MA
• 5 portfolio companies

The fund backs data-centric companies building predictive models for financial trading and decentralized marketplaces.

• Fintech
• AI / ML
• Other

• Seed, Series A
• $200K – $3.0M
• London, UK
• 2 portfolio companies

Invests in next-gen predictive AI tools reshaping revenue intelligence and B2B SaaS ecosystems.

• AI / ML
• Other

• Seed, Pre-Seed, Series A
• $500K – $5.0M
• New York, NY
• 2 portfolio companies

Established early-stage investor in software and enterprise technology. A reasonable fit for a scalable agency OS with strong commercial traction.

• SaaS
• Enterprise
• AI / ML

• Seed, Series A
• $500K – $3.0M
• Chicago, IL
• 1 portfolio company

Focuses on emerging companies leveraging AI to solve pressing enterprise challenges, including sales and marketing enablement.

• Other
• SaaS
• AI / ML

• Seed, Series A
• $200K – $5.0M
• San Francisco, CA
• 149 portfolio companies

Focuses on innovative media technologies using AI to redefine content interactions.

• Other
• AI / ML

• Series A
• $3.0M – $10.0M
• Sydney, Australia