Seed AI & Machine Learning Venture Capital Firms

Browse 2,902 venture capital firms that invest in AI & Machine Learning startups at the Seed stage. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified Seed AI & Machine Learning VC firms

SaaSXponential

Focuses exclusively on B2B SaaS companies innovating integration technology powered by AI.

  • SaaS
  • AI / ML
  • Other
  • Pre-Seed, Seed
  • $300K – $1.0M
  • Paris, France
  • 1 portfolio company

SaaSify Capital

Invests in SaaS solutions that enhance business processes and corporate training ecosystems.

  • SaaS
  • Other
  • AI / ML
  • Seed, Pre-Seed
  • $1.0M – $4.0M
  • San Francisco, CA
  • 21 portfolio companies

SaaStr Fund

Fund dedicated exclusively to B2B/B2D/AI companies building business software, APIs, and tools that enable software creation. It is positioned for AI-native enterprise software with clear product-mark...

  • SaaS
  • AI / ML
  • Other
  • Seed, Series A
  • $750K – $5.0M
  • San Francisco, California
  • 13 portfolio companies

SaasCatalyst Fund

SaasCatalyst Fund is dedicated to supporting early-stage B2B SaaS ventures with innovative AI/ML applications.

  • SaaS
  • AI / ML
  • Enterprise
  • Pre-Seed, Seed
  • $750K – $2.5M
  • Austin, TX
  • 10 portfolio companies

Saddle Ridge Ventures

Invests in early-stage companies pioneering innovative workflow automation and AI-driven SaaS solutions.

  • Other
  • SaaS
  • AI / ML
  • Pre-Seed, Seed
  • $250K – $2.0M
  • Boulder, CO
  • 1 portfolio company

SafeFuture Ventures

SafeFuture Ventures funds early-stage startups building AI-driven public safety and emergency infrastructure.

  • Other
  • AI / ML
  • Developer Tools
  • Seed, Pre-Seed
  • $100K – $1.5M
  • Berlin, Germany
  • 8 portfolio companies

SafeSystems VC

Specialized in companies mitigating systemic risks caused by autonomous and agentic AI, particularly in industrial and enterprise-scale environments.

  • Other
  • SaaS
  • AI / ML
  • Seed
  • $500K – $3.0M
  • Berlin, Germany
  • 2 portfolio companies

Safi Holdings

Safi Holdings invests in Fintech and PropTech companies with innovative solutions tailored for the African market.

  • Fintech
  • Real Estate
  • AI / ML
  • Pre-Seed, Seed
  • $250K – $2.0M
  • Lagos, Nigeria
  • 1 portfolio company

Saga Ventures

Seed-focused fund with a small partnership that backs deep company-building in infrastructure-like categories, including industrial automation and AI infrastructure. The fund emphasizes fundamentals-d...

  • Other
  • AI / ML
  • Enterprise
  • Pre-Seed, Seed
  • $2.0M – $4.0M
  • 44 portfolio companies

Sagely Ventures

Sagely Ventures invests in AI-driven B2B SaaS platforms with unique data-powered applications, particularly those enhancing customer acquisition and retention processes.

  • AI / ML
  • SaaS
  • Other
  • Pre-Seed, Seed
  • $500K – $3.0M
  • Denver, CO
  • 9 portfolio companies

Sahara Ventures

Sahara Ventures invests in logistics and marketplace tech solutions that enhance supply chain efficiency in East Africa.

  • Other
  • Marketplace
  • Consumer
  • Pre-Seed, Seed
  • $100K – $1.5M
  • Dar es Salaam, Tanzania
  • 5 portfolio companies

Sales Catalyst Fund

Specializes in investing in startups that transform sales processes through innovative technology solutions.

  • Other
  • AI / ML
  • Pre-Seed, Seed
  • $200K – $1.5M
  • Chicago, IL
  • 1 portfolio company

Sales Tech Angels

Early believers in cutting-edge Sales Tech and tools that redefine team productivity.

  • Other
  • AI / ML
  • Pre-Seed, Seed
  • $50K – $300K
  • London, UK
  • 1 portfolio company

Salutem Capital

Focused on scaling medtech innovations in underpenetrated markets like LatAm.

  • Other
  • Healthcare
  • AI / ML
  • Pre-Seed, Seed
  • $750K – $2.5M
  • New York, NY
  • 33 portfolio companies

Samaipata

Samaipata focuses on digital platforms and tech ecosystems at their earliest stages, particularly in B2B SaaS and AI-powered marketplaces.

  • SaaS
  • Marketplace
  • AI / ML
  • Pre-Seed, Seed
  • $700K – $2.5M
  • Madrid, Spain
  • 43 portfolio companies

Sanara Capital

Dedicated health-tech fund investing in digital health, bio-convergence, and medical devices for Israeli-related startups in Israel and abroad. Positioned as a specialist platform with a portfolio spa...

  • Healthcare
  • Other
  • AI / ML
  • Seed, Series A, Series B, series-c
  • 22 portfolio companies

Sand Hill Angels Ventures

Early-stage fund focused on AI and SaaS solutions, particularly in business applications like sales enablement.

  • AI / ML
  • SaaS
  • Other
  • Seed
  • $250K – $3.0M
  • Palo Alto, CA
  • 2 portfolio companies

Sands Capital Ventures

Growth-oriented early-stage investor with a venture practice that backs enterprise software and select industrial technology companies.

  • Enterprise
  • Other
  • SaaS
  • Pre-Seed, Seed, Series A
  • $500K – $3.0M
  • Arlington, Virginia
  • 19 portfolio companies

Sankofa Ventures

Focused on startups building technology for Africa, particularly in education, media, and public sector digitization. Strong alignment with localized AI innovation.

  • Other
  • AI / ML
  • EdTech
  • Seed
  • $250K – $5.0M
  • Lagos, Nigeria
  • 6 portfolio companies

Sapling Ventures

Focuses on early-stage technology startups transforming HR Tech and recruitment processes, prioritizing ML/AI-driven solutions for talent acquisition.

  • Other
  • AI / ML
  • SaaS
  • Pre-Seed, Seed
  • $500K – $1.5M
  • New York, NY
  • 2 portfolio companies

Sapphire Sport (Sapphire Ventures)

Enterprise software specialist with an early-stage practice (Sapphire Sport) investing in seed/early rounds.

  • Enterprise
  • SaaS
  • Other
  • Seed, Series A
  • $1.0M – $3.0M
  • Palo Alto, CA
  • 6 portfolio companies

Sarah Smith Fund

AI-native solo GP fund; launched via rolling fund, then traditional Fund I; check size ≈ US$250K typically into early-stage with deep founder/market fit.

  • AI / ML
  • Fintech
  • Other
  • Pre-Seed, Seed
  • $250K+
  • USA (via AngelList)
  • 49 portfolio companies

Sassafras Capital

Targets enterprise software solutions with a strong AI component, focusing on innovations that drive enterprise productivity and efficiency.

  • Enterprise
  • AI / ML
  • Seed
  • $1.5M – $4.0M
  • Chicago, IL
  • 1 portfolio company

Savanna Innovation Capital

Investing in Ghanaian fintech startups that bring digital transformation to traditional financial services.

  • Fintech
  • Other
  • Real Estate
  • Pre-Seed, Seed
  • $100K – $300K
  • Accra, Ghana
  • 27 portfolio companies

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