AI & Machine Learning Venture Capital Firms

Investing in open-source tools that empower developers and enterprise solutions at the pre-seed stage.

• Other
• Developer Tools
• SaaS

• Pre-Seed
• $75K – $150K
• San Francisco, CA
• 20 portfolio companies

Invests in operator-founders in Europe & Africa building early stage tech companies with strong domains in fintech, SaaS, AI, focusing also on future commerce, work and health.

• Fintech
• AI / ML
• SaaS

• Pre-Seed
• Up to $150K
• London, UK
• 3 portfolio companies

Focuses on funding next-gen operational analytics and AI-driven data tools for enterprise applications.

• Other
• AI / ML
• Developer Tools

• Seed, Pre-Seed
• $300K – $4.0M
• San Francisco, CA
• 2 portfolio companies

Investing in modern tools for operations leaders at manufacturing enterprises; focusing on B2B SaaS companies disrupting procurement, logistics, and supply chain management.

• Other
• SaaS
• Enterprise

• Seed
• $250K – $3.0M
• Austin, TX
• 1 portfolio company

Dedicated to early-stage HealthTech solutions leveraging AI and machine learning to optimize operations in hospitals and healthcare organizations.

• Healthcare
• Other
• Enterprise

• Pre-Seed, Seed
• $250K – $3.0M
• Austin, TX
• 1 portfolio company

Focuses on startups leveraging IoT and AI to transform operational systems in manufacturing and energy.

• Other
• AI / ML

• Seed
• $750K – $2.5M
• Boston, MA
• 1 portfolio company

Invests in early-stage RevOps and operational SaaS companies aiming to transform revenue-generating processes for mid-market and enterprise customers.

• Other
• SaaS
• Enterprise

• Pre-Seed, Seed
• $750K – $2.5M
• Seattle, WA
• 6 portfolio companies

Investing in startups that leverage technology to optimize supply chain and operational efficiencies.

• Other
• Enterprise
• AI / ML

• Pre-Seed, Seed
• $500K – $2.0M
• San Jose, California
• 1 portfolio company

Optica Venture Partners focuses on investing in cutting-edge optical computing technologies and AI infrastructure advancements.

• AI / ML
• Other
• Healthcare

• Pre-Seed, Seed
• $1.0M – $5.0M
• Cambridge, UK
• 7 portfolio companies

Invests in HealthTech startups delivering measurable improvements in clinical outcomes through software and AI-driven solutions.

• Healthcare
• AI / ML
• Other

• Series A, Seed
• $1.5M – $10.0M
• Palo Alto, CA
• 4 portfolio companies

Dedicated to enhancing AI infrastructure capabilities and investing in companies transforming machine learning efficiencies.

• AI / ML
• Developer Tools

• Pre-Seed, Seed
• $500K – $3.0M
• Boston, MA
• 5 portfolio companies

Focused on backing AI-driven B2B SaaS companies driving organizational efficiency and decision-making.

• Other
• SaaS
• AI / ML

• Pre-Seed, Seed
• $300K – $2.0M
• London, UK
• 2 portfolio companies

Focuses on early-stage technology companies leveraging AI to create scalable SaaS solutions.

• SaaS
• AI / ML
• Enterprise

• Pre-Seed, Seed
• $1.0M – $3.0M
• Austin, TX
• 2 portfolio companies

AI-focused venture fund built around foundational technologies, infrastructure, developer tools, and specialized frameworks. The strategy is aimed at software layers that underpin enterprise AI adopti...

• AI / ML
• Developer Tools
• Climate / Energy

• Pre-Seed, Seed
• 13 portfolio companies

Optum Ventures invests from seed through growth in companies at the intersection of healthcare and technology, including value-based care delivery, enterprise software and enabling infrastructure, and...

• Healthcare
• AI / ML

• Seed, Series A
• $1.5M – $5.0M
• Boston, Massachusetts, United States
• 1 portfolio company

Dedicated to investing in transformative ERP solutions that enhance business processes in supply chains.

• Other
• SaaS
• AI / ML

• series seed
• $1.5M – $2.5M
• Paris, France
• 9 portfolio companies

Supports e-commerce innovations that revolutionize digital selling and multi-channel retail operations.

• Other
• Marketplace
• SaaS

• Seed
• $300K – $800K
• New York, NY
• 13 portfolio companies

Orbit Labs backs founders building productivity-focused B2B SaaS tools with AI/ML integration.

• SaaS
• Other
• Enterprise

• Pre-Seed, Seed
• $300K – $1.5M
• San Francisco, CA
• 39 portfolio companies

Orbit Partners invests in startups utilizing AI to enhance efficiency in sales and business operations within SMBs.

• AI / ML
• Other
• SaaS

• Pre-Seed, Seed
• $400K – $2.0M
• Toronto, Canada
• 5 portfolio companies

Invests in early-stage companies in Asia and emerging markets using AI to solve high-impact problems in visual data intelligence, logistics, and operational efficiency.

• AI / ML
• SaaS
• Other

• Pre-Seed, Seed
• $50K – $250K
• Singapore
• 2 portfolio companies

Invests in startups advancing geospatial mapping and AI applications for urban infrastructure and global development.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $3.0M
• San Francisco, CA
• 1 portfolio company

Orbx Ventures focuses on early-stage investments in B2B SaaS and AI startups, with an emphasis on companies building revenue-generation tools for marketing and sales teams.

• SaaS
• AI / ML
• Other

• Pre-Seed, Seed
• $250K – $1.0M
• Austin, TX
• 2 portfolio companies

Invests exclusively in AI orchestration tools and DevOps workflows targeting enterprise environments.

• Other
• Developer Tools
• SaaS

• Pre-Seed, Seed
• $250K – $1.5M
• Berlin, Germany
• 2 portfolio companies

Focuses exclusively on addressing developer and engineering pain points by investing in tools that streamline workflows, increase productivity, and enable enterprise-wide adoption.

• Developer Tools
• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $1.5M
• Portland, OR
• 5 portfolio companies