AI & Machine Learning Venture Capital Firms

Focused on automation and AI-driven platforms transforming industries from the ground up.

• AI / ML
• Marketplace

• seed+, Series A
• $1.0M – $15.0M
• Seattle, WA
• 2 portfolio companies

Harlem Capital invests in early-stage founders—especially those from overlooked backgrounds—who are building the future of technology via AI, software, infrastructure, and solutions that redefine lega...

• SaaS
• Enterprise
• Other

• Pre-Seed, Seed
• $1.0M – $2.5M
• New York City, United States
• 18 portfolio companies

Harmonix Ventures invests in innovative startups transforming the music industry using technology. They focus on companies enabling new business models and monetization strategies for music creators.

• Other
• Healthcare
• EdTech

• Pre-Seed, Seed
• $500K – $3.0M
• Los Angeles, CA
• 8 portfolio companies

Investing in early-stage digital health and AI solutions that improve healthcare accessibility and outcomes in African markets.

• Healthcare
• AI / ML

• Seed
• $50K – $250K
• Nairobi, Kenya
• 11 portfolio companies

Harpoon Ventures focuses on dual-use technologies that build scalable infrastructure for applications in defense, security, and enterprise.

• Other
• AI / ML
• Enterprise

• Seed, Series A
• $500K – $2.0M
• San Diego, CA
• 16 portfolio companies

Harrison Metal invests in early-stage companies building transformative solutions in enterprise software and SaaS, with a focus on leveraging AI and analytics.

• SaaS
• Enterprise
• AI / ML

• Seed
• $500K – $1.0M
• Palo Alto, CA, USA
• 30 portfolio companies

Participated in a pre-seed AI diagnostics round, implying openness to technically ambitious healthtech ventures.

• Other
• AI / ML

• Pre-Seed, Seed

Focuses on early-stage innovation in blockchain, DeFi, and fintech across emerging markets like Africa and Southeast Asia.

• Other
• Fintech
• AI / ML

• Seed, pre-series-a
• $500K – $10.0M
• Singapore
• 3 portfolio companies

Invests in private companies developing therapeutics and vaccines for human use, across all development stages and modalities, with a preference for capital efficiency, well-understood disease biology...

• Healthcare
• AI / ML
• Other

• Seed, Pre-Seed
• $250K – $2.0M
• Doylestown, Pennsylvania, United States
• 7 portfolio companies

Invests in technology-driven marketplaces and SMB tools solving inefficiencies in everyday services.

• Marketplace
• Other
• Consumer

• Seed, Pre-Seed
• $100K – $1.0M
• London, UK
• 103 portfolio companies

HatchPoint specializes in early HealthTech and regulatory tools that address compliance and streamline operations in highly regulated environments like healthcare.

• Healthcare
• Other
• SaaS

• Pre-Seed, Seed
• $100K – $1.0M
• Chicago, IL
• 1 portfolio company

Focused exclusively on crypto, decentralized financial solutions, and Web3 technology that builds next-generation infrastructure.

• Other
• AI / ML
• Developer Tools

• Pre-Seed, Seed
• $100K – $2.0M
• New York, NY
• 34 portfolio companies

Haveli invests in high-quality technology companies—especially enterprise software, gaming, horizontal and vertical applications, infrastructure software, and cybersecurity—where it can make control o...

• Other
• SaaS
• Developer Tools

• Pre-Seed, Seed
• $250K – $2.0M
• Austin, Texas, USA
• 2 portfolio companies

Focused exclusively on early-stage startups building innovative marketplaces or platforms for home services or homeowner-focused solutions.

• Other
• Real Estate
• Marketplace

• Seed, Pre-Seed
• $50K – $250K
• Austin, TX
• 28 portfolio companies

Agency-adjacent investor profile implied by the martech and adtech focus, with a good fit for software that improves media and content operations. Stronger if the product is sold through agencies or s...

• Other
• SaaS
• Developer Tools

• Pre-Seed, Seed
• 14 portfolio companies

Focuses on AI-driven B2B SaaS solutions that automate workflows for small and medium-sized businesses.

• Other
• SaaS
• AI / ML

• Pre-Seed, Seed
• $300K – $2.0M
• Austin, TX
• 7 portfolio companies

Headline’s regional early-stage funds invest locally in Seed and Series A companies across the US, Europe, Brazil, and Asia; its global growth fund invests in Series B and later-stage companies.

• Other
• Marketplace
• Consumer

• Pre-Seed, Seed
• $250K – $1.5M
• San Francisco, United States
• 40 portfolio companies

Focuses on pioneering AI-driven solutions to solve complex health challenges.

• Healthcare
• AI / ML

• Pre-Seed, Seed
• $750K – $2.5M
• Boston, MA

Focused on early-stage investments in AI-driven solutions for healthcare regulation and compliance.

• Healthcare
• Other
• AI / ML

• Pre-Seed
• $500K – $5.0M
• Boston, MA
• 2 portfolio companies

Focused on early-stage HealthTech startups leveraging AI and SaaS to improve healthcare operations and patient outcomes.

• Healthcare
• SaaS
• Other

• Pre-Seed, Seed, Series A
• $500K – $3.0M
• San Francisco, CA
• 51 portfolio companies

Invests in early-stage SaaS companies with applications in the healthcare and fitness sectors, aiming to modernize legacy systems.

• SaaS
• Healthcare
• AI / ML

• Seed
• $300K – $2.0M
• San Francisco, CA
• 58 portfolio companies

Focuses on investing in early-stage companies that leverage AI to innovate healthcare solutions, focusing on cost-efficiency.

• Healthcare
• AI / ML

• Pre-Seed, Seed
• $500K – $3.0M
• Boston, MA
• 1 portfolio company

Focuses on early-stage investments in healthcare logistics innovations integrating AI for better operational efficiency.

• Healthcare
• Other
• AI / ML

• Pre-Seed
• $1.0M – $3.0M
• Boston, MA

Invests in innovative health system technologies, focusing on SaaS and AI advancements.

• Healthcare
• Other
• SaaS

• Pre-Seed
• $1.0M – $3.0M
• Austin, TX
• 5 portfolio companies