Venture Capital Firms in the USA

Healthcare-focused investor backing companies transforming care delivery, operations, and patient engagement. Often relevant for software-enabled healthcare businesses with clear workflow value.

• Healthcare
• Other

• Seed, Series A
• New York, New York

Nyca Partners invests from seed to scale in early-stage fintech and financial infrastructure, targeting founders modernizing payments and transactions, risk, capital formation, digital advice, and fin...

• Fintech
• Other

• Seed, Series A, Pre-Seed
• $2.3M – $30.0M
• New York, United States
• 3 portfolio companies

Writing first checks for innovative webinar software and B2B SaaS companies broadening the communication landscape.

• Other
• SaaS
• Enterprise

• Pre-Seed, Seed
• $100K – $500K
• New York, NY
• 2 portfolio companies

Invests in early-stage companies revolutionizing the nutrition and food tech industries.

• Food / AgTech
• Consumer

• Seed
• $1.0M – $3.0M
• Chicago, IL
• 1 portfolio company

Specializes in pre-launch and early-stage healthcare startups innovating in medical devices and technology-enabled solutions.

• Healthcare
• Other
• EdTech

• Pre-Seed, Seed
• $1.0M – $4.0M
• Boston, MA
• 2 portfolio companies

Focuses on innovative healthtech solutions, particularly in diagnostics and life sciences tools. Highly active in regulated lab automation.

• Other
• Healthcare

• Seed
• $1.0M – $10.0M
• New York, NY
• 2 portfolio companies

Obscura Ventures invests in startups building next-gen solutions for digital and physical security, particularly in GovTech and adjacent B2B SaaS spaces.

• Other
• SaaS

• Pre-Seed, Seed
• $250K – $2.0M
• Austin, TX
• 2 portfolio companies

Invests solely in observability and developer tool startups that enhance system visibility and reliability.

• Other
• Developer Tools

• Pre-Seed, Seed
• $750K – $2.5M
• San Francisco, CA

Investing in early-stage startups creating marketplaces and SaaS solutions with data-driven insights.

• Marketplace
• Other

• Pre-Seed, Seed
• $250K – $1.0M
• Austin, Texas
• 2 portfolio companies

Investing in novel observability and SRE tooling for optimizing and automating system reliability.

• Other
• SaaS
• Enterprise

• Pre-Seed
• $50K – $200K
• Austin, TX
• 5 portfolio companies

Obsidian Ventures focuses on transformational technologies in energy and quantum computing sectors, aiming to support startups that drive sustainable advancements.

• Other

• Pre-Seed
• $500K – $2.0M
• Austin, TX

Obvious Ventures invests thematically across three pillars—planetary health, human health, and economic health—backing exceptional founders building breakthrough, world-positive companies that transfo...

• Consumer
• Healthcare
• Climate / Energy

• Seed, Series A
• $5.0M – $12.0M
• San Francisco, United States
• 10 portfolio companies

Early-stage PropTech-focused fund investing in software and platforms for real estate and construction.

• Real Estate
• SaaS
• Marketplace

• Pre-Seed, Seed
• $250K – $2.0M
• Miami, FL
• 43 portfolio companies

Targets investments in early-stage watersport and travel technology companies facilitating direct consumer engagement.

• Other
• Healthcare
• SaaS

• Pre-Seed
• $100K – $250K
• New York, NY
• 38 portfolio companies

Oceanus Capital specializes in early-stage investments in maritime and defense technologies that offer critical infrastructure security solutions.

• Other
• Security
• Developer Tools

• Seed
• $500K – $2.0M
• Boston, MA
• 1 portfolio company

Focuses on innovative platform businesses that enable digital marketplaces and enhance peer-to-peer transactions.

• Marketplace
• Other
• Consumer

• Seed
• $250K – $1.0M
• San Francisco, CA
• 2 portfolio companies

Focuses on startups leveraging AI to improve decision-making in enterprise environments, including risk assessment and productivity optimization.

• AI / ML
• Enterprise
• Other

• Pre-Seed, Seed
• $100K – $1.0M
• Salt Lake City, UT
• 2 portfolio companies

Offbeat Ventures focuses on the future of work and creator economy, backing startups that redefine how creators engage and monetize their work.

• Other
• Marketplace

• Pre-Seed, Seed
• $250K – $1.0M
• Austin, TX
• 1 portfolio company

Offline is an early-stage venture fund and studio backing founders who build differently and technology that serves humanity. Its stated focus is where online and offline experiences meet.

• Other

• Pre-Seed
• $100K – $1.5M
• Mill Valley, California, United States
• 18 portfolio companies

Specialized in backing early-stage startups monetizing carbon offsets and clean energy solutions through tech platforms.

• Climate / Energy
• SaaS
• Other

• Seed
• $250K – $7.0M
• Austin, TX
• 2 portfolio companies

Focused exclusively on early-stage investments in oil & gas marketplace businesses looking to streamline procurement and distribution.

• Other
• Marketplace

• Pre-Seed
• $500K – $2.0M
• Dallas, TX
• 1 portfolio company

Seed-stage venture firm with exposure to real estate software and data-driven workflow tools. Suitable for B2B products that operationalize brokerage and transactions.

• Real Estate
• SaaS
• Consumer

• Seed
• Boston, Massachusetts
• 42 portfolio companies

Strategic seed investor in identity, security, and adjacent enterprise software ecosystems.

• Enterprise
• Security
• Developer Tools

• Pre-Seed, Seed
• $250K – $2.0M
• San Francisco, CA
• 42 portfolio companies

Focused exclusively on early-stage HealthTech solutions that streamline hospital operations, improve patient outcomes, or optimize payer reimbursement.

• Healthcare
• SaaS
• Other

• Seed, Pre-Seed
• $250K – $2.0M
• Boston, MA
• 26 portfolio companies