Series A Venture Capital Firms

Early-stage medtech and life sciences investor focusing on chronic disease therapeutics and diagnostics, including molecular diagnostics and advanced imaging, in Europe and the US.

• Other
• Developer Tools
• Consumer

• Seed, Series A
• 5 portfolio companies

OMERS Ventures backs transformative marketplace and SaaS platforms disrupting traditional consumer and business workflows.

• Marketplace
• SaaS
• Other

• Seed, Series A
• $1.0M – $5.0M
• Toronto, Canada
• 2 portfolio companies

Seed-stage digital health specialist focused on care delivery innovation and digital health infrastructure.

• Healthcare
• AI / ML
• EdTech

• Seed, Series A
• $250K – $1.5M
• Chicago, IL
• 35 portfolio companies

Invests in early-stage companies commercializing university-based or deep science innovations in biotech, medtech, and healthtech.

• Healthcare
• Other

• Seed, Pre-Seed, Series A
• $250K – $2.0M
• Bala Cynwyd, PA
• 2 portfolio companies

Invest in early-stage Fintech and e-commerce platforms addressing underserved customer segments in global markets.

• Fintech
• Other

• Seed, Series A
• $500K – $4.0M
• London, UK
• 2 portfolio companies

Obvious Ventures invests thematically across three pillars—planetary health, human health, and economic health—backing exceptional founders building breakthrough, world-positive companies that transfo...

• Consumer
• Healthcare
• Climate / Energy

• Seed, Series A
• $5.0M – $12.0M
• San Francisco, United States
• 10 portfolio companies

Investing in innovative logistics and supply chain technologies with global potential, focused on Latin America and underrepresented markets.

• Other
• SaaS

• Seed, Series A
• $1.0M – $3.0M
• Santiago, Chile
• 1 portfolio company

Invests in African fintech and platforms facilitating cross-border commerce and payments, with a preference for startups unlocking trade between Africa and global markets.

• Fintech
• Other

• Seed, Series A
• $100K – $750K
• Lagos, Nigeria
• 1 portfolio company

UK-based fund investing in European startups transforming consumer and retail sectors, with emphasis on digital-first businesses.

• Consumer
• Other

• Pre-Seed, Seed, Series A
• $250K – $1.0M
• London, UK
• 159 portfolio companies

Omega Funds focuses on transformative advances across the life sciences, backing innovators in drug discovery and biotech tools.

• Other
• Healthcare

• Pre-Seed, Seed, Series A
• $250K – $2.0M
• Boston, MA
• 2 portfolio companies

Invests in cutting-edge biotech innovations and AI applications revolutionizing healthcare delivery.

• Healthcare
• Other

• seed+, Series A
• $2.0M – $8.0M
• Boston, MA
• 2 portfolio companies

Focused on scalable consumer tech solutions solving critical challenges for the mass Indian market.

• Consumer
• EdTech
• Other

• Seed, Series A
• $500K – $5.0M
• Mumbai, India
• 2 portfolio companies

Invests exclusively in next-gen omnichannel commerce startups redefining in-store and ecommerce experiences through personalization and data.

• Other

• Seed, Series A
• $1.0M – $5.0M
• London, UK
• 2 portfolio companies

Focuses exclusively on technological advancements in online commerce platforms.

• Other

• Seed, Series A
• $500K – $3.0M
• New York, NY
• 1 portfolio company

OpenOcean backs European-founded, AI-driven companies that use data as a competitive moat, particularly in AI-enabled services and automation, scalable AI computation, and agentic infrastructure and d...

• Deep Tech
• SaaS
• Developer Tools

• Seed, Pre-Seed, Series A
• $2.3M – $5.7M
• Helsinki, Finland
• 8 portfolio companies

Investing in transformative SaaS solutions for freight and transportation sectors, driving operational efficiency.

• SaaS
• Other

• Seed, Series A
• $1.0M – $4.0M
• Seattle, WA
• 1 portfolio company

Specializes in AI-driven operational intelligence solutions targeting B2B startups serving the SMB market.

• Other

• Seed, Series A
• $1.0M – $5.0M
• Chicago, IL
• 1 portfolio company

Invests in HealthTech startups delivering measurable improvements in clinical outcomes through software and AI-driven solutions.

• Healthcare
• AI / ML
• Other

• Series A, Seed
• $1.5M – $10.0M
• Palo Alto, CA
• 4 portfolio companies

Investing in the cybersecurity and critical infrastructure innovation space, focusing on pre-seed startups tackling enterprise-level risks.

• Security
• Other

• Seed, Series A
• $500K – $2.5M
• New York, NY
• 2 portfolio companies

Optum Ventures invests from seed through growth in companies at the intersection of healthcare and technology, including value-based care delivery, enterprise software and enabling infrastructure, and...

• Healthcare
• AI / ML

• Seed, Series A
• $1.5M – $5.0M
• Boston, Massachusetts, United States
• 1 portfolio company

Focused on early-stage B2B SaaS and marketplace startups in underrepresented hubs including the Midwest.

• Marketplace
• SaaS

• Seed, Series A
• $500K – $4.0M
• Chicago, IL, USA
• 10 portfolio companies

Invests in scalable telecommunications and e-commerce platforms with a Southeast Asian focus.

• Other

• Series A
• $75K – $250K
• Kuala Lumpur, MY
• 1 portfolio company

Targets companies with innovative solutions in orthotic devices and prosthetic technology.

• Other

• Seed, Series A
• $750K – $3.5M
• Seattle, WA
• 2 portfolio companies

Focuses on compliant DeFi protocols, blockchain infrastructure, and institutional finance applications.

• Other

• Seed, Series A
• $1.0M – $5.0M
• San Francisco, CA
• 1 portfolio company