Series A AI & Machine Learning Venture Capital Firms

Specialist healthtech fund backing technology-enabled health companies with a deliberate weighting toward prevention and early intervention. It explicitly cites AI/ML clinical decision support, diagno...

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed, Series A
• $250K – $1.0M
• 1 portfolio company

Corporate venture arm focused on AI and related startup opportunities. Relevant for AI applications that improve workflows and enterprise productivity.

• AI / ML
• Other
• Enterprise

• Seed, Series A
• San Francisco, California

Regional specialist fund targeting southeastern US-based enterprise software companies in compliance and cybersecurity domains.

• SaaS
• Other
• Security

• Seed, Series A
• $500K – $3.0M
• Durham, North Carolina
• 126 portfolio companies

Invests in life-sciences industrials—tools, technologies, and services that support the discovery, development, and production of biopharmaceutical therapies.

• AI / ML
• Other
• Enterprise

• Seed, Series A
• $200K – $2.0M
• New York City, United States
• 13 portfolio companies

Focuses on SMB tool innovations and AI technologies within the EMEA region, supporting early-stage companies with regional scalability potential.

• Other
• AI / ML

• Pre-Seed, Seed, Series A
• $100K – $1.0M
• Berlin, Germany
• 2 portfolio companies

Focused on innovation in AI and digital-first solutions for mental and emotional health.

• Healthcare
• Other
• AI / ML

• Seed, Series A
• $2.0M – $7.0M
• Palo Alto, CA
• 2 portfolio companies

Regional early-stage investor with a commerce and retail orientation across MENA and adjacent markets. The fund backs companies in e-commerce, retail, and advertising, which maps well to the digital s...

• Other
• SaaS
• Fintech

• Pre-Seed, Seed, Series A
• $1.1M – $15.0M
• United Arab Emirates
• 6 portfolio companies

Large European venture platform with a dedicated seed strategy and strong enterprise software and AI exposure. The right partner can support globally ambitious software infrastructure companies.

• Enterprise
• AI / ML
• Developer Tools

• Seed, Series A
• Stockholm, Sweden
• 10 portfolio companies

Invests in cutting-edge technologies with a focus on AI innovations in consumer and travel sectors.

• AI / ML
• Other

• Pre-Seed, Seed, Series A
• Tokyo, Japan

Eclipse invests in and co-builds companies transforming physical industries and critical systems. Its focus includes industries such as manufacturing, supply chain, energy, transportation, and defense...

• Other
• Enterprise
• SaaS

• Seed, Series A
• $5.0M – $25.0M
• Palo Alto, California, United States
• 7 portfolio companies

Eco Venture Group aims to fund scalable solutions in climate and sustainability.

• Climate / Energy
• Other
• AI / ML

• Seed, Series A
• $1.0M – $3.0M
• Boston, MA
• 6 portfolio companies

EcoDerm Ventures backs sustainable and nature-inspired cosmetic innovations with proven efficacy data.

• Healthcare
• Other
• AI / ML

• Seed, Series A
• $500K – $4.0M
• Boston, MA
• 1 portfolio company

Specializes in early AI solutions for industrial applications, including IoT-enhanced manufacturing and supply chain disruptions.

• AI / ML
• Other
• Developer Tools

• Seed, Series A
• $750K – $5.0M
• Palo Alto, CA
• 2 portfolio companies

Invests in industrial and logistics technology startups leveraging sensors, edge computing, and AI for operational optimization.

• Other
• AI / ML
• EdTech

• Seed, Series A
• $750K – $5.0M
• Chicago, IL
• 9 portfolio companies

Diversified investment firm with deep media/entertainment exposure; occasionally backs enabling technology.

• Other
• AI / ML
• Healthcare

• Growth, Series A, Seed
• $500K – $20.0M
• Greenwich, CT
• 49 portfolio companies

Supports companies aiming to revolutionize logistics and supply chain processes through innovative software solutions.

• Other
• SaaS
• AI / ML

• Seed, Series A
• $500K – $5.0M
• San Carlos, CA
• 26 portfolio companies

The fund invests in applied AI innovations that augment decision-making for enterprises, particularly in fintech and wealth management.

• AI / ML
• SaaS
• Other

• seed+, Series A
• $1.0M – $5.0M
• Montreal, Canada
• 24 portfolio companies

Focuses on software companies with strong growth and go-to-market efficiency. While not a MarTech fund, it may back software that sits in the revenue and activation stack for brands.

• SaaS
• Enterprise
• Developer Tools

• Seed, Series A
• $1.0M – $4.0M
• San Mateo, California
• 5 portfolio companies

The leading enterprise cloud investor. Backed Salesforce, Zoom, and more.

• SaaS
• Developer Tools
• AI / ML

• Series A, Series B
• $10.0M – $30.0M
• US-SF
• 13 portfolio companies

Emerging Growth Partners supports transformative B2B and enterprise technology startups, with a focus on scalable SaaS and machine learning applications.

• SaaS
• Enterprise
• AI / ML

• Seed, Series A
• $1.5M – $5.0M
• Chicago, IL
• 2 portfolio companies

Deep tech fund targeting breakthrough technologies in AI infrastructure, semiconductors, and hardware critical for advanced computing.

• Deep Tech
• AI / ML
• Other

• Seed, Series A
• $750K – $5.0M
• Boston, MA
• 2 portfolio companies

Focused on energy-sector blockchain solutions, including tokenization of resources like oil and gas.

• Other
• AI / ML

• Seed, Series A
• $1.0M – $10.0M
• Houston, TX
• 2 portfolio companies

Energy Nexus Fund backs startups at the intersection of technology and sustainability, focusing on scalable energy solutions.

• Climate / Energy
• Other
• Developer Tools

• Seed, Series A
• $1.0M – $5.0M
• Denver, CO
• 14 portfolio companies

Investing in technologies that enhance engagement and analytics within the sports sector.

• Other
• Developer Tools
• SaaS

• Series A
• $1.0M – $3.0M
• Los Angeles, CA
• 10 portfolio companies