Seed AI & Machine Learning Venture Capital Firms

HealthX invests at the seed stage in scalable digital health solutions that make healthcare more accessible, efficient, and affordable.

• Healthcare
• AI / ML
• Marketplace

• Pre-Seed, Seed
• $500K – $3.0M
• Madison, United States
• 1 portfolio company

Focuses on digital solutions transforming healthcare practice and operations.

• Healthcare
• AI / ML

• Seed
• $800K – $2.0M
• Los Angeles, CA
• 1 portfolio company

Invests in early-stage companies developing software platforms to streamline B2B workflows in healthcare and pharmaceutical industries.

• Healthcare
• SaaS
• Enterprise

• Pre-Seed, Seed
• $75K – $300K
• Austin, TX
• 1 portfolio company

Health-tech venture firm focused on modernizing care delivery and healthcare operations. The startup’s autonomous practice administration and billing stack aligns with provider-ops infrastructure inve...

• Healthcare
• SaaS
• Other

• Seed, Series A
• New York, New York
• 21 portfolio companies

Healthy Ventures is a seed-stage digital health specialist with a stated check range that includes the target raise size. Its portfolio in digital health suggests fit for an enterprise software layer ...

• Healthcare
• Developer Tools
• AI / ML

• Seed
• $500K – $2.0M
• 26 portfolio companies

Investing in next-gen cardiovascular HealthTech solutions with a focus on AI integration and remote monitoring.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $1.0M – $3.0M
• Austin, TX
• 8 portfolio companies

HeartBeat Ventures invests in early-stage companies transforming healthcare delivery using AI and analytics.

• Healthcare
• Other
• Developer Tools

• Pre-Seed, Seed
• $250K – $2.0M
• Austin, TX
• 17 portfolio companies

Heartcore backs European technology founders at the early stage, from inception to Series A, with a stated focus on founders building outlier companies.

• Other
• SaaS
• AI / ML

• Pre-Seed, Seed
• $500K – $2.0M
• Copenhagen, Denmark
• 23 portfolio companies

Invests in innovative solutions in healthcare that leverage digital technology to improve healthcare outcomes.

• Healthcare
• SaaS
• AI / ML

• Pre-Seed, Seed, Series A
• $250K – $5.0M
• New York, NY
• 24 portfolio companies

HeliosVC invests in high-performance data center and AI capacity across Europe, focusing on green energy-powered infrastructure for industrial and sovereign applications.

• Other
• AI / ML
• Developer Tools

• Seed, Series A
• $1.0M – $5.0M
• Munich, Germany
• 2 portfolio companies

B2B SaaS-focused micro VC actively backing early-stage marketplace startups that streamline industry-specific workflows.

• SaaS
• Marketplace
• Consumer

• Pre-Seed, Seed
• $500K – $2.0M
• Austin, TX
• 2 portfolio companies

Focuses on consumer and AI-powered startups that foster human connection.

• Other
• AI / ML
• Consumer

• Pre-Seed, Seed
• $500K – $5.0M
• London, UK
• 2 portfolio companies

Investing in women-led and women-focused startups, particularly innovations that address maternal and digital health.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $50K – $250K
• San Diego, CA
• 2 portfolio companies

Focused exclusively on enabling early-stage, lean AI startups through targeted investments in SaaS-based enterprise solutions.

• Other
• Enterprise
• AI / ML

• Pre-Seed, Seed
• $250K – $1.0M
• Atlanta, GA
• 1 portfolio company

Focuses on technology that revolutionizes interactive entertainment, particularly AR/VR, gaming, and AI-powered platforms.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $1.0M
• Los Angeles, CA
• 1 portfolio company

Seed-focused emerging manager from Israel investing in deep technical enterprise software, including cybersecurity and cloud infrastructure.

• Security
• Developer Tools
• Other

• Pre-Seed, Seed
• $500K – $1.5M
• Tel Aviv, Israel
• 17 portfolio companies

Investor cluster behind AI-native video creation and video reasoning platforms. Strong adjacency to an AI workspace for ad teams because the product operates in creative production infrastructure.

• AI / ML
• Other
• Developer Tools

• Series A, Seed
• 2 portfolio companies

High Alpha invests in early-stage enterprise software companies across North America, alongside proprietary opportunities launched from its studio.

• SaaS
• Enterprise
• Other

• Seed, Series A
• $1.0M – $5.0M
• Indianapolis, United States
• 95 portfolio companies

Invests in high-performance Web3 and decentralized application (dApp) infrastructure including blockchain technology for DeFi and gaming ecosystems.

• Other
• AI / ML
• Developer Tools

• Seed, Series A
• $500K – $5.0M
• Tel Aviv, Israel
• 2 portfolio companies

HighConviction Ventures backs founders creating user-friendly blockchain and crypto tools aimed at driving mass adoption of financial decentralization.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $1.0M
• Denver, CO
• 1 portfolio company

Investing in fundamental science-driven startups addressing bottlenecks in AI compute, semiconductor performance, and specialized manufacturing materials.

• Deep Tech
• Other
• AI / ML

• Pre-Seed, Seed
• $500K – $2.5M
• Chicago, IL
• 2 portfolio companies

Hitchhiker Ventures backs founders building B2B SaaS tools, particularly in the AI-driven workflow optimization and enterprise software spaces.

• SaaS
• Other
• Enterprise

• Pre-Seed, Seed
• $250K – $750K
• Austin, TX
• 2 portfolio companies

Investor backing enterprise voice-AI infrastructure in regulated verticals. Potentially aligned with customer support automation and enterprise communications.

• AI / ML
• Enterprise

• Seed

HomeLab Ventures invests in startups creating next-generation home automation and smart living experiences.

• Other
• AI / ML

• Pre-Seed, Seed
• $300K – $1.5M
• Seattle, WA
• 1 portfolio company