Seed AI & Machine Learning Venture Capital Firms

Cardinal Ventures is a micro-fund focusing on seed-stage investments in AI and telehealth innovations.

• Other
• AI / ML
• Healthcare

• Seed
• $50K – $200K
• Palo Alto, CA
• 150 portfolio companies

Invests in HealthTech solutions that leverage AI to bring efficiency and safety to care facilities.

• Healthcare
• AI / ML

• Seed
• $1.0M – $3.0M
• Austin, TX
• 2 portfolio companies

Focused exclusively on early-stage enterprise AI solutions that enhance business intelligence and operational efficiency.

• Other
• SaaS
• Enterprise

• Seed
• $1.0M – $3.0M
• San Francisco, CA
• 1 portfolio company

Focused on investing in startups that revolutionize 3D design and architecture tech, especially those with novel integrations of AI and BIM.

• Other
• Real Estate
• AI / ML

• Pre-Seed, Seed
• $50K – $200K
• San Francisco, CA
• 38 portfolio companies

Backing early-stage companies that leverage AI/ML to build scalable disruptive solutions, with a strong interest in workflow-enabled tools.

• AI / ML
• Other

• Pre-Seed, Seed
• $100K – $2.0M
• San Francisco, CA
• 2 portfolio companies

Focuses on African startups with scalable models addressing local infrastructure gaps in logistics, e-commerce, and financial technology.

• Other
• Marketplace
• Fintech

• Seed, Pre-Seed
• $50K – $500K
• Cape Town, South Africa
• 61 portfolio companies

Investing in breakthrough biotechnologies that enhance health and sustainability.

• Healthcare
• AI / ML
• Other

• Pre-Seed, Seed
• $300K – $1.5M
• Boston, MA
• 3 portfolio companies

Catalyst Data Partners supports innovative solutions in AI and enterprise data operations that optimize complex datasets.

• Other
• AI / ML
• Enterprise

• Seed
• $500K – $1.5M
• Austin, TX
• 16 portfolio companies

Invests in marketplaces and SaaS tools enhancing workflow, particularly with collaborative tech or commercial transaction layers.

• Marketplace
• Other
• Consumer

• Seed, Series A
• $1.0M – $3.0M
• Chicago, IL
• 14 portfolio companies

Dedicated to supporting wealth management and AI startups transforming personal finance through technology.

• Other
• AI / ML
• SaaS

• Pre-Seed, Seed
• $1.0M – $3.0M
• San Francisco, CA
• 15 portfolio companies

Focused on funding hardware startups developing AI accelerators, semiconductor innovations, and advanced wireless/computing technologies.

• Other
• Deep Tech
• AI / ML

• Pre-Seed, Seed
• $500K – $3.0M
• Toronto, Canada
• 1 portfolio company

Catalyst Quantum Fund is committed to AI-driven B2B SaaS startups, investing in technologies that redefine enterprise efficiencies.

• AI / ML
• SaaS
• Enterprise

• Seed, Series A
• $500K – $1.5M
• Boston, MA
• 72 portfolio companies

Dedicated to supporting startups building the next wave of tools for retailers, with an emphasis on operational efficiency and reducing environmental impact.

• Other
• AI / ML

• Pre-Seed, Seed
• $300K – $2.0M
• Chicago, IL
• 1 portfolio company

Backing founders building the future of retail operations with SaaS tools and AI models that streamline inventory, marketing, and customer engagement.

• Other
• SaaS
• AI / ML

• Pre-Seed, Seed
• $150K – $1.0M
• New York City, NY
• 2 portfolio companies

Focused on cultivating early-stage Fintech and SaaS companies that are aiming to disrupt traditional industries with transformative technology.

• Fintech
• SaaS
• Enterprise

• Seed
• $1.0M – $5.0M
• Boston, MA
• 1 portfolio company

Invests in scalable workforce development and talent solutions for modern enterprises.

• Other
• SaaS
• AI / ML

• Pre-Seed, Seed
• $250K – $3.5M
• Palo Alto, CA
• 2 portfolio companies

Focuses on early-stage investments in AI-driven B2B SaaS solutions for mid-market operations and supply chain.

• SaaS
• AI / ML
• Other

• Seed
• $1.0M – $3.0M
• Austin, TX
• 1 portfolio company

Backing companies transforming workflow efficiency through AI-enabled tools and systems, with a focus on enterprise-scale applications.

• Other
• AI / ML
• Enterprise

• Seed, Series A
• $1.0M – $4.0M
• Denver, CO
• 40 portfolio companies

Focused on hardware-heavy, deep-tech startups leveraging advanced materials and clean energy solutions.

• Other
• AI / ML
• Healthcare

• Seed
• $500K – $2.0M
• Austin, TX
• 73 portfolio companies

Solo-GP early-stage fund focused exclusively on enterprise software. The firm targets technical and software-centric companies, including developer tooling and infrastructure-adjacent products.

• Enterprise
• Developer Tools
• SaaS

• Pre-Seed, Seed
• $250K – $1.0M
• San Francisco, California

Strategic investor in technologies adjacent to Caterpillar's ecosystem, including heavy equipment, jobsite productivity, and machine intelligence.

• Other
• Real Estate
• Climate / Energy

• Seed, Series A, strategic
• Irving, TX
• 17 portfolio companies

Causeway invests in growth-stage companies in sports, fitness, and related industries. It applies its experience and networks to support portfolio companies as a value-added partner.

• Other
• AI / ML

• Seed, Series A
• $1.0M – $10.0M
• Cambridge, Massachusetts, United States
• 2 portfolio companies

Cavallo invests in innovative AgTech and FoodTech companies, leveraging technology to advance sustainable production and distribution systems.

• Food / AgTech
• Other
• Climate / Energy

• Seed
• $500K – $3.0M
• San Francisco, USA
• 44 portfolio companies

Cedar Hill Ventures invests in data-driven enterprise SaaS startups solving automation and financial services problems.

• AI / ML
• SaaS
• Enterprise

• Seed
• $500K – $2.5M
• Austin, TX
• 1 portfolio company