Pre-Seed Venture Capital Firms

F-Prime invests in healthcare—including therapeutics, medtech, and healthtech and services—and in technology, including enterprise software, fintech, frontier tech, and crypto. It favors early-stage i...

• Enterprise
• Other
• Healthcare

• Pre-Seed, Seed
• $1.0M – $30.0M
• Cambridge, Massachusetts, United States
• 12 portfolio companies

Healthcare-focused venture firm with offices in Nashville and Charlotte that invests in digital health and technology-enabled healthcare services. The firm’s second fund targets first-time fundraising...

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed, Series A
• Nashville, TN
• 60 portfolio companies

FEN Ventures focuses on vertical SaaS businesses targeting underserved industries like retail logistics and small restaurant operations, creating efficiencies through custom workflows and technology.

• SaaS
• Other

• Pre-Seed, Seed
• $250K – $2.0M
• Miami, FL
• 3 portfolio companies

Invests in early-stage food & beverage brands scaling via franchise models or operationally strong unit expansion.

• Other
• Food / AgTech
• Consumer

• Pre-Seed, Seed, Series A
• $250K – $3.0M
• Austin, TX
• 2 portfolio companies

Invests in early-stage fintech, healthtech, and AI companies, pairing capital with a growth, finance, and talent platform.

• Fintech
• Healthcare
• AI / ML

• Pre-Seed, Seed, Series A
• $250K – $500K
• San Francisco, CA
• 41 portfolio companies

FLVC invests in pre-seed and seed companies, particularly focusing on B2B and SaaS solutions.

• Other
• SaaS
• Enterprise

• Pre-Seed, Seed
• $250K – $750K
• San Francisco, CA
• 2 portfolio companies

FREES Ventures specializes in supporting emerging vertical SaaS companies across nontraditional regions in the US.

• SaaS

• Pre-Seed, Seed
• $100K – $750K
• Austin, TX
• 2 portfolio companies

FSDAi supports early-stage FinTech innovations in Africa that focus on expanding financial inclusion, particularly for marginalized and underserved populations.

• Other
• Fintech

• Pre-Seed, Seed
• $100K – $1.0M
• Nairobi, Kenya
• 1 portfolio company

Invests in early-stage B2B software and enterprise solutions improving efficiency and operations.

• SaaS
• Enterprise
• Other

• Pre-Seed, Seed
• $250K – $2.0M
• Seattle, WA
• 2 portfolio companies

Invests exclusively in LatAm-focused B2B SaaS and financially disruptive technologies, partnering with technical founders solving high-impact risk and efficiency challenges.

• SaaS
• Security
• Fintech

• Pre-Seed, Seed
• $250K – $1.0M
• Mexico City, Mexico
• 2 portfolio companies

Invests early in transformative digital businesses, especially in Enterprise SaaS and Climate-based impact solutions.

• SaaS
• Other
• Fintech

• Pre-Seed, Seed
• $200K – $3.0M
• Lisbon, Portugal
• 8 portfolio companies

Specializes in investing in innovative fashion tech solutions, emphasizing sustainability and tech adoption for European retail chains and brands.

• Other
• Climate / Energy

• Seed, Pre-Seed
• $750K – $5.0M
• Paris, France
• 2 portfolio companies

Focus on advancing the management of facilities through innovative technology.

• Other
• Real Estate

• Pre-Seed
• $60K – $300K
• Austin, TX
• 1 portfolio company

Specializes in startups transforming facility management through advanced PropTech solutions.

• Other
• Real Estate

• Pre-Seed
• $1.0M – $4.5M
• Chicago, IL
• 1 portfolio company

Factor[e] Ventures backs early-stage ventures addressing energy, agriculture, and mobility in emerging markets, leveraging technology to deliver impact.

• Other
• Deep Tech

• Pre-Seed, Seed
• $50K – $500K
• Fort Collins, CO / Nairobi, Kenya
• 7 portfolio companies

Factorial Capital backs infrastructure-heavy software startups, often at very early stages. It is relevant for companies building technical control layers and data plumbing.

• AI / ML
• Other
• Developer Tools

• Pre-Seed, Seed
• $100K – $2.0M
• San Francisco, California
• 30 portfolio companies

Investing in startups innovating within industrial and manufacturing technology, with a focus on software platforms and automation solutions.

• Other

• Pre-Seed
• $100K – $1.0M
• Chicago, IL
• 2 portfolio companies

Micro fund investing in early-stage advanced manufacturing and industrial automation companies leveraging AI and robotics.

• Other
• Deep Tech
• AI / ML

• Seed, Pre-Seed
• $250K – $1.5M
• Pittsburgh, PA
• 16 portfolio companies

Faculty Group appears in early cross-border fintech financings and is likely to favor infrastructure-heavy, technical financial products. It is a plausible specialist for payment rails and FX workflow...

• Fintech
• Other
• Developer Tools

• Seed, Pre-Seed
• 12 portfolio companies

Investing in emerging technologies that overhaul financial services and enterprise operations through dedicated tech stacks.

• Fintech
• SaaS
• Enterprise

• Pre-Seed, Series A
• $750K – $5.0M
• Chicago, Illinois
• 3 portfolio companies

Focuses on FaithTech and businesses with a strong mission-aligned impact, serving Christian entrepreneurs and communities.

• Other

• Pre-Seed, Seed
• $100K – $1.0M
• Palo Alto, CA
• 1 portfolio company

Falak Startups focuses on seed-stage MENA startups, particularly those solving regional infrastructure challenges like transportation and safety.

• Other
• Healthcare
• Developer Tools

• Seed, Pre-Seed
• $100K – $500K
• Cairo, Egypt
• 2 portfolio companies

Focused on consumer innovations that serve family needs, emphasizing health, education, and active lifestyle products suitable for children and parents alike.

• Consumer
• Other
• AI / ML

• Seed, Pre-Seed
• $50K – $1.0M
• Portland, OR
• 29 portfolio companies

Invests in early-stage startups at the intersection of crowdfunding, fintech, and social media.

• Other
• Fintech

• Pre-Seed
• $100K – $300K
• Austin, TX