Pre-Seed Venture Capital Firms

Invests specifically in the next wave of life science tools startups with a SaaS component.

• Other
• SaaS

• Pre-Seed
• $1.0M – $4.0M
• Chicago, IL
• 1 portfolio company

A life-sciences and diagnostics-oriented investor with likely interest in biomarker and assay-adjacent software. Good fit for biomarker prediction workflows.

• Other
• Healthcare

• Pre-Seed, Seed

BioVenture Partners backs transformative innovations in life sciences and healthtech, with a focus on data-centric solutions.

• Healthcare
• Other
• Developer Tools

• Pre-Seed, Seed
• $500K – $3.0M
• Boston, MA
• 1 portfolio company

Healthcare and HealthTech-focused fund investing at pre-seed and seed stages in transformational companies, particularly impactful solutions for multi-practitioner practices.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $500K – $3.0M
• Cambridge, MA
• 14 portfolio companies

Focuses on early-stage companies with technology for biodiversity impact and sustainable practices.

• SaaS
• Food / AgTech
• AI / ML

• Pre-Seed
• $500K – $2.5M
• San Francisco, CA
• 1 portfolio company

Biolumina Ventures focuses on early-stage biotech startups that are leveraging cutting-edge AI and data analytics to transform drug discovery processes.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $500K – $3.0M
• Austin, TX
• 6 portfolio companies

Invests in early-stage companies developing groundbreaking biotech and regenerative medicine solutions.

• Healthcare
• Other

• Pre-Seed, Seed
• $50K – $250K
• Boston, MA
• 5 portfolio companies

Focused exclusively on investing in startups that innovate with biomarkers to improve preventive health outcomes.

• Other
• Healthcare

• Pre-Seed
• $500K – $3.0M
• Boston, MA

Focused on innovations in renewable biomanufacturing technologies and sustainable health solutions.

• Climate / Energy
• Healthcare
• Other

• Pre-Seed, Seed
• $250K – $1.0M
• San Francisco, CA
• 1 portfolio company

Early-stage fund dedicated to microbiome innovation, funding transformative health solutions targeting specific microbiota like oral health.

• Other
• Healthcare

• Pre-Seed, Seed
• $200K – $3.0M
• Boston, MA
• 2 portfolio companies

Invests in AI and hardware innovations that enhance human-machine interactions through advanced biomechanics technologies.

• AI / ML
• Other
• Healthcare

• Pre-Seed, Seed
• $300K – $1.5M
• Boston, MA

Investing in startups that use biosignals for innovative applications in wearables and B2B SaaS solutions.

• Other
• SaaS

• Pre-Seed, Seed
• $50K – $1.5M
• Austin, TX

Backing B2B SaaS and CleanTech innovators in Africa to drive sustainable growth through technology.

• Climate / Energy
• SaaS

• Pre-Seed, Seed
• $300K – $3.0M
• Abidjan, Côte d'Ivoire

Focused on funding startups in the biotech R&D sector with a mission to transform scientific findings into practical solutions through advanced automation technologies.

• Other

• Pre-Seed, Series A
• $200K – $2.0M
• San Diego, CA
• 1 portfolio company

Blockchain-focused fund investing in regulated crypto payment infrastructure and B2B platforms supporting compliance-heavy needs.

• Other

• Pre-Seed, Seed
• $250K – $1.0M
• Austin, TX
• 1 portfolio company

Dedicated to unearthing disruptive DeFi and crypto solutions across emerging markets.

• Other

• Pre-Seed, Seed
• $300K – $2.0M
• Lisbon, Portugal
• 1 portfolio company

Focuses on building Web3 infrastructure with an emphasis on payments and blockchain rails for emerging markets.

• Other

• Seed, Pre-Seed
• $500K – $3.0M
• Miami, FL
• 2 portfolio companies

Backing startups focused on Bitcoin and cryptocurrency payments infrastructure with a focus on emerging markets.

• Other
• Developer Tools

• Pre-Seed, Seed
• $50K – $500K
• Berlin, Germany
• 2 portfolio companies

BiteSize Ventures backs startups creating next-generation tools that improve operational efficiencies in restaurants and food services.

• Other
• EdTech
• Food / AgTech

• Pre-Seed, Seed
• $200K – $2.5M
• Austin, TX
• 14 portfolio companies

Focused exclusively on blockchain, crypto, and decentralized finance projects.

• Other
• AI / ML

• Pre-Seed, Seed
• $50K – $250K
• Berlin, Germany
• 2 portfolio companies

A pan-African angel syndicate investing in innovative tech companies solving socio-economic challenges.

• AI / ML
• Other
• EdTech

• Pre-Seed, Seed
• $10K – $300K
• Johannesburg, South Africa
• 2 portfolio companies

Focuses exclusively on Black tech entrepreneurs innovating in tech-enabled industries, including marketplaces and retail tech.

• Marketplace
• Other

• Pre-Seed, Seed
• $50K – $250K
• California, USA
• 1 portfolio company

Dedicated to investing in startups that contribute to the empowerment and connectivity of the Black diaspora globally.

• Other

• Pre-Seed
• $200K – $1.0M
• Accra, Ghana
• 1 portfolio company

Empowering Black entrepreneurs by investing in innovative marketplace and e-commerce solutions.

• Marketplace
• Other
• Consumer

• Pre-Seed
• $500K – $2.0M
• Atlanta, GA
• 1 portfolio company