Venture Capital Firms in the USA

Focuses on synthetic biology and next-gen healthcare tools for accelerated R&D processes.

• Other
• Healthcare

• Pre-Seed
• $500K – $3.0M
• San Francisco, CA
• 1 portfolio company

Invests in AI-driven startups transforming key industries, including logistics and enterprise SaaS.

• AI / ML
• SaaS
• Other

• Seed
• $500K – $2.5M
• Palo Alto, CA
• 2 portfolio companies

Funding innovations in SaaS platforms that leverage AI for healthcare solutions.

• Healthcare
• AI / ML
• SaaS

• Pre-Seed
• $500K – $2.5M
• Austin, TX
• 1 portfolio company

Invests in innovative supply chain management solutions integrated with enterprise software to enhance operational efficiency.

• Other
• Enterprise

• Pre-Seed
• $1.0M – $3.0M
• Austin, TX

Invests in early-stage companies that leverage AI to transform business intelligence and knowledge sharing in enterprise settings.

• Other
• SaaS
• EdTech

• Seed
• $500K – $2.0M
• New York, NY
• 15 portfolio companies

Synaptic Capital targets AI-powered SaaS and marketplaces that disrupt traditional industries, primarily focusing on seed-stage companies with global aspirations.

• Other
• Fintech
• Marketplace

• Seed, Series A
• $750K – $3.5M
• San Francisco, CA
• 2 portfolio companies

Investing in early-stage AI technologies with applications in education and personalized learning experiences.

• AI / ML
• EdTech
• Enterprise

• Pre-Seed
• $500K – $1.0M
• Austin, TX
• 5 portfolio companies

SyncCapital aims to synergize AI and financial technologies to create disruptive business solutions at the seed stage.

• AI / ML
• Fintech

• Seed
• $100K – $200K
• Los Angeles, CA
• 1 portfolio company

SyncFlow Capital targets innovative B2B SaaS platforms that enhance enterprise efficiency and collaboration.

• SaaS
• Enterprise
• Other

• Pre-Seed
• $250K – $1.0M
• Chicago, IL
• 6 portfolio companies

Dedicated to investing in research tech and data analytics startups that enable enterprises to unlock scientific potential through technology.

• Other
• Developer Tools

• Seed
• $300K – $2.5M
• San Francisco, CA
• 1 portfolio company

Invests in early-stage biotech startups solving industry challenges through advanced technologies.

• Healthcare

• Seed
• $500K – $2.0M
• Boston, MA
• 1 portfolio company

Focuses on B2B SaaS startups leveraging decision management techniques to optimize enterprise operations.

• SaaS
• Other
• Enterprise

• Seed
• $750K – $2.0M
• Denver, CO
• 1 portfolio company

Focused on empowering B2B SaaS companies in fintech with disruptive potential.

• SaaS
• Fintech

• Pre-Seed
• $1.0M – $3.5M
• Chicago, IL

SynergyLoop Ventures invests in process automation and SaaS-driven operational tools for underserved business verticals.

• SaaS
• Marketplace
• Enterprise

• Seed, Series A
• $750K – $4.0M
• Chicago, IL
• 2 portfolio companies

Invests in early-stage research tool innovations with a focus on improving academic workflows and collaboration.

• Other
• SaaS

• Pre-Seed
• $1.0M – $3.0M
• Chicago, IL
• 1 portfolio company

Invests in companies that revolutionize coding experiences and developer efficiency.

• Developer Tools
• AI / ML

• Seed
• $1.5M – $2.5M
• New York, NY
• 35 portfolio companies

Investing exclusively in the DevOps and developer tools ecosystem, Syntax Ventures backs early-stage companies building infrastructure for modern software development.

• Developer Tools
• Other

• Pre-Seed, Seed
• $250K – $2.0M
• Austin, TX
• 2 portfolio companies

Synthetic Ventures focuses on groundbreaking AI and robotics startups, helping them scale innovative solutions in industrial contexts.

• Other
• AI / ML

• Seed
• $1.0M – $3.0M
• San Francisco, CA

Investing in startups enhancing system observability and incident management capabilities for enterprise IT teams.

• Other
• Enterprise
• SaaS

• Pre-Seed
• $100K – $300K
• San Francisco, CA
• 1 portfolio company

System Initiative specializes in tools, platforms, and infrastructure supporting automation and developer productivity.

• Other
• Developer Tools
• Enterprise

• Pre-Seed, Seed
• $200K – $2.0M
• San Francisco, CA
• 2 portfolio companies

Emerging fund backing infrastructure-first startups that solve engineering bottlenecks using AI-powered solutions.

• Other
• Developer Tools
• AI / ML

• Pre-Seed, Seed
• $300K – $1.5M
• Chicago, IL
• 13 portfolio companies

Systema Ventures invests in emerging enterprise software tools that enable automation in software processes and business workflows.

• SaaS
• Developer Tools
• Enterprise

• Seed
• $200K – $2.0M
• Austin, TX
• 1 portfolio company

Systematic Ventures funds foundational tools for software teams, targeting emerging AI and DevOps innovations.

• Other
• Developer Tools

• Pre-Seed, Seed
• $300K – $2.0M
• New York, NY
• 2 portfolio companies

Laser-focused on niche tech solutions serving restaurant ecosystems, specifically targeting fragmented independent operators.

• Other
• SaaS

• Pre-Seed, Seed
• $150K – $750K
• Los Angeles, CA
• 1 portfolio company