Venture Capital Firms in the USA

Investing in AI-powered enterprise tools and infrastructure from non-coastal hubs, with a strong focus on Midwest and Northeast founders.

• AI / ML
• Enterprise
• SaaS

• Seed
• $150K – $750K
• Pittsburgh, PA
• 2 portfolio companies

Steel Vault Ventures invests in foundational cybersecurity solutions focused on quantification of cyber risk for mid-market and enterprise customers.

• Security
• Other
• SaaS

• Seed
• $250K – $3.0M
• Denver, CO
• 1 portfolio company

SteelSky Ventures is the leading venture capital fund solely dedicated to investing in women’s health and healthcare innovation.

• Other
• Healthcare

• Seed, Pre-Seed
• $250K – $3.0M
• Atlanta, GA
• 22 portfolio companies

Backing tech startups solving operational challenges in industrial and metal fabrication sectors.

• Other

• Seed, Series A
• $500K – $6.0M
• Dallas, Texas
• 1 portfolio company

Invests in companies targeting federal government innovation, military services, and veteran needs.

• Other

• Pre-Seed, Seed
• $50K – $2.5M
• Washington, DC
• 1 portfolio company

Backs transformative companies in crypto infrastructure using innovative blockchain solutions.

• Other
• Fintech
• Developer Tools

• Pre-Seed, Seed
• $50K – $250K
• New York, NY
• 8 portfolio companies

Invests in early-stage fintech and blockchain startups driving financial innovation.

• Other
• Fintech

• Pre-Seed
• $250K – $1.0M
• San Francisco, CA

Stellation backs mission-driven, intellectually curious founding teams at pre-seed and seed, investing as early as possible. Its interests include AI productivity, social graphs, creative communities,...

• Marketplace
• Other
• Consumer

• Pre-Seed, Seed
• $250K – $2.5M
• Brooklyn, New York, United States
• 7 portfolio companies

Backs startups focused on high-impact tech solutions in government and critical infrastructure sectors.

• Other
• SaaS
• Developer Tools

• Seed
• $500K – $2.0M
• Chicago, IL
• 5 portfolio companies

Laser-focused on supporting Bitcoin-specific startups driving adoption and transaction innovation.

• Other
• Fintech

• Seed, Pre-Seed
• $250K – $3.5M
• San Francisco, CA
• 9 portfolio companies

Focuses on scaling platforms for enabling efficient real estate flipping, development tools, and PropTech marketplaces.

• Real Estate
• Marketplace
• Other

• Seed
• $500K – $3.5M
• Phoenix, AZ
• 1 portfolio company

Seed and Series A fund focused on enterprise blockchain applications, Web3 scalability, and decentralized security solutions.

• Other
• Security
• Enterprise

• Seed, Series A
• $1.0M – $5.0M
• Miami, FL
• 2 portfolio companies

Backing founders working on advanced storage and cloud management tools, with emphasis on decentralized solutions.

• Other
• Developer Tools

• Pre-Seed, Seed
• $250K – $2.0M
• Remote - US Focus
• 2 portfolio companies

Focused exclusively on investing in boutique hotel acquisitions and renovations, tailoring investments to maximize returns through property rebranding, operational upgrades, and software implementatio...

• Other
• Real Estate
• SaaS

• Pre-Seed, Seed
• $1.0M – $5.0M
• San Francisco, CA
• 46 portfolio companies

Enterprise-focused early-stage VC with 25+ years of B2B investing.

• SaaS
• Enterprise
• Developer Tools

• Seed, Series A
• $500K – $8.0M
• US-SF
• 13 portfolio companies

Focused on AI-driven automation solutions targeting inefficiencies in SMB operations, with a preference for B2B SaaS models.

• SaaS
• Other
• Developer Tools

• Pre-Seed, Seed
• $250K – $3.0M
• Austin, TX
• 18 portfolio companies

Investing in technology that enhances human potential through AI and future-of-work innovations.

• AI / ML
• Other
• Fintech

• Pre-Seed, Seed
• $250K – $2.0M
• New York, NY
• 39 portfolio companies

Investing in seed-stage software companies encoding expert judgment into AI workflows for enterprise strategy.

• AI / ML
• Other
• SaaS

• Seed
• $250K – $1.5M
• Boston, MA
• 14 portfolio companies

Investing in early-stage B2B software startups revolutionizing consulting outputs into scalable AI solutions.

• Other
• Enterprise
• SaaS

• Pre-Seed, Seed
• $300K – $2.0M
• Chicago, IL
• 2 portfolio companies

Shaping the future of betting through strategic investments in platforms that offer community and technological engagement.

• Other
• Fintech
• SaaS

• Seed
• $250K – $700K
• Las Vegas, NV
• 5 portfolio companies

Strategic Health Capital invests in startups that address critical gaps in the healthcare sector with technology-driven solutions.

• Healthcare

• Seed
• $500K – $2.0M
• Chicago, IL
• 1 portfolio company

Focused on early-stage companies using AI for cost optimization and procurement efficiencies in supply chain-heavy industries.

• Other
• AI / ML

• Seed
• $500K – $2.5M
• Boston, MA
• 2 portfolio companies

Investing in cutting-edge aerospace, defense, and energy storage ventures with dual-use potential for commercial and government applications.

• Other

• Pre-Seed, Seed
• $400K – $3.0M
• Huntsville, AL
• 2 portfolio companies

Stratoplus Ventures focuses on startups innovating within the aerospace and additive manufacturing fields, providing early-stage capital to high-potential companies.

• Other

• Seed
• $500K – $3.0M
• Austin, TX
• 1 portfolio company