Venture Capital Firms in the USA

Invests in the intersection of enterprise software and AI, leveraging signal processing innovations.

• Enterprise
• AI / ML
• SaaS

• Pre-Seed, Seed
• $1.0M – $4.0M
• Minneapolis, MN
• 28 portfolio companies

Backing innovative startups in AI-enabled security systems for enterprise applications.

• Security
• AI / ML

• Pre-Seed
• $200K – $1.0M
• Chicago, IL

Separate Ventures invests in the technologies underpinning modern workflows, with a particular interest in tools for remote hiring, asynchronous collaboration, and next-gen workforce enablement.

• Other
• SaaS

• Pre-Seed, Seed
• $250K – $1.5M
• Austin, TX
• 2 portfolio companies

Sequoia invests across seed, early and growth‐stage technology companies—especially those solving large problems with exceptional founders, strong product/market fit, and markets that can scale to sig...

• Consumer
• Enterprise
• Fintech

• Seed, Series A, Series B
• $500K – $200.0M
• Menlo Park, United States
• 19 portfolio companies

Sequoia partners with ambitious founders early—even when a company is only an idea—and supports them from company-building through IPO and beyond.

• Enterprise
• SaaS

• Pre-Seed, Seed
• $500K – $1.0M
• Menlo Park, California, United States
• 3 portfolio companies

Sequoia Scouts write small pre-seed checks via operator/investor scouts; can be a path to later Sequoia attention.

• Other
• Fintech
• AI / ML

• Pre-Seed
• $50K – $500K
• Menlo Park, CA
• 11 portfolio companies

Scout network enabling pre-seed checks from trusted operators and investors connected to Sequoia.

• Other
• Enterprise
• Consumer

• Pre-Seed
• $25K – $250K
• Menlo Park, CA
• 12 portfolio companies

Invests in early-stage technology startups across high-growth sectors, using curated portfolios and co-investment. The firm does not publish a verifiable current range for typical initial check sizes.

• Enterprise
• SaaS
• AI / ML

• Seed+, Series A
• $500K – $3.0M
• Milton, Georgia, United States
• 100 portfolio companies

Supporting promising HealthTech innovations focused on personalized care and women's wellness.

• Healthcare

• Pre-Seed
• $750K – $5.0M
• San Francisco, CA
• 1 portfolio company

Serena Ventures backs bold founders reshaping how we live, work, move, and connect, with a purpose to expand access, ownership, and opportunity at scale — especially supporting underrepresented founde...

• SaaS
• Developer Tools
• AI / ML

• Seed, Series A
• $100K – $500K
• San Francisco, California, United States
• 5 portfolio companies

Seed and Series A investor with broad software and AI interest. Strong option for AI-driven SaaS with diverse founder profiles and market potential.

• AI / ML
• SaaS
• Other

• Seed, Series A
• $500K – $5.0M
• Los Angeles, California

Serial Metric Ventures focuses exclusively on early-stage investments in industrial automation, CAD software, and AI-driven engineering tools.

• Other
• SaaS
• AI / ML

• Pre-Seed, Seed
• $500K – $3.0M
• Chicago, IL

Serra Ventures invests at the intersection of agriculture, technology, and sustainability with a focus on high-impact innovation.

• Food / AgTech
• AI / ML
• SaaS

• Pre-Seed, Seed
• $100K – $1.0M
• Champaign, IL
• 6 portfolio companies

Focuses exclusively on innovative technologies that enhance operations in field services and small businesses.

• Other

• Pre-Seed, Seed
• $200K – $750K
• Chicago, IL

Operator networks that frequently back pre-seed B2B SaaS and help with GTM (member-driven investing).

• SaaS
• Other
• Enterprise

• Pre-Seed
• $100K – $1.0M
• San Francisco, CA
• 3 portfolio companies

Dedicated to B2B SaaS platforms revamping the service industry with technology-driven frameworks.

• SaaS
• Other

• Seed, Series A
• $750K – $5.0M
• Chicago, IL
• 1 portfolio company

Strategic venture arm investing in enterprise software that advances digital workflows, IT, security, and automation.

• Enterprise
• Other
• SaaS

• Seed, Series A
• $500K – $5.0M
• Santa Clara, CA
• 3 portfolio companies

Invests in B2B SaaS platforms that streamline operations within service industries, with a strong focus on automation.

• SaaS
• Other

• Seed, Pre-Seed
• $500K – $3.0M
• Glendale, CA
• 2 portfolio companies

Seven Seven Six describes itself as an early-stage technology investor backing founders building transformative companies. Its publicly stated interests include people-first companies shaping the futu...

• SaaS

• Pre-Seed, Seed
• $250K – $1.0M
• Jupiter, Florida, United States
• 2 portfolio companies

Committed to investing in consumer SaaS startups that integrate financial intelligence for enhanced user decision-making.

• SaaS
• Other
• Consumer

• Pre-Seed, Seed
• $100K – $250K
• Boston, MA
• 1 portfolio company

Focuses on early-stage B2B SaaS companies solving enterprise IT pain points or operational inefficiencies.

• SaaS
• Enterprise
• AI / ML

• Seed, Pre-Seed
• $250K – $3.5M
• New York, NY
• 2 portfolio companies

SeventySix Capital invests in startups innovating in sports technology, AI, and data analytics, particularly those optimizing business processes.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $2.0M
• Conshohocken, PA
• 22 portfolio companies

Dedicated to advancing the NFT and metaverse economy, including digital assets and entertainment-focused blockchain innovations.

• Other

• Seed
• $100K – $500K
• Miami, FL
• 2 portfolio companies

Sfermion invests in web3 and crypto-native consumer applications with strong community and network characteristics. It is comfortable with products that blend marketplace mechanics, identity, and on-c...

• Other
• Consumer
• AI / ML

• Seed, Series A
• $250K – $2.0M
• New York, NY
• 9 portfolio companies