Venture Capital Firms in the USA

PreSeed Ventures is a US-based micro VC fund dedicated to pre-seed and early-stage B2B startups.

• Other

• Pre-Seed
• $750K – $2.5M
• New York, NY
• 2 portfolio companies

Preface Ventures invests at the earliest stages (pre-seed to seed), targeting 'Frontier Enterprise' infrastructure—enterprise software, security, fintech, healthcare data—often as the first check befo...

• SaaS
• Marketplace
• Fintech

• Seed, Pre-Seed
• $750K – $2.0M
• New York, United States
• 2 portfolio companies

Invests in startups shaping the future of work and consumer-led technology solutions.

• Other
• Consumer

• Pre-Seed, Seed
• $50K – $250K
• New York, NY
• 32 portfolio companies

PrepTech Capital invests in startups revolutionizing the test preparation sector with innovative technological solutions.

• Other
• EdTech

• Pre-Seed
• $250K – $2.0M
• Boston, MA

Focused on niche hospitality and AI-driven wellness startups, particularly those integrating technology with elevated travel and tourism experiences.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $3.0M
• Santa Barbara, CA
• 2 portfolio companies

Focuses on early-stage investments in game-related ecosystems, multiplayer innovations, and platforms improving developer and creator workflows.

• Other
• Developer Tools

• Seed, Series A
• $500K – $7.0M
• Austin, TX
• 32 portfolio companies

Focused exclusively on early-stage preventive health solutions.

• Other

• Pre-Seed
• $750K – $2.0M
• Austin, TX

Focuses on software solutions in electronic health record enhancement, clinical decision-making, and clinician productivity optimization.

• Other
• Healthcare
• SaaS

• Seed
• $250K – $750K
• Los Angeles, CA
• 1 portfolio company

NYC-based early-stage VC investing in B2B SaaS and fintech with hands-on GTM help.

• SaaS
• Fintech
• Other

• Seed, Series A
• $1.0M – $3.0M
• New York, NY
• 14 portfolio companies

Primary leads pre-seed and seed rounds, backing AI-native, product-driven founders with conviction; they prefer structural moats via proprietary data, network effects, and deep domain expertise across...

• SaaS
• Other
• Fintech

• Pre-Seed, Seed
• $100K – $5.0M
• New York, United States
• 10 portfolio companies

Backs breakthrough technologies addressing the root causes of climate change, with a focus on scalable science-led solutions for emissions reductions.

• Other

• Seed, Series A, Series B
• $500K – $5.0M
• Cambridge, MA
• 44 portfolio companies

Investing in the future of intelligent enterprise solutions that redefine productivity through AI platforms.

• Other

• Seed
• $750K – $4.5M
• Chicago, IL
• 1 portfolio company

Provides catalytic capital to supercharge climate innovations, spanning fusion energy and hard engineering tech.

• Climate / Energy
• Other

• Pre-Seed, Seed
• $500K – $3.0M
• Boston, MA
• 18 portfolio companies

Prime Movers Lab invests in early-stage, breakthrough scientific startups—deep tech founded by inventors—that tackle globally important industries such as energy, transportation, infrastructure, manuf...

• Other

• Pre-Seed, Seed, Series A
• $250K – $2.2M
• Teton Village / Jackson, Wyoming, United States
• 34 portfolio companies

Prime Nexus Ventures invests in high-growth marketplaces and e-commerce platforms leveraging AI and data-driven strategies.

• Marketplace
• Fintech
• Other

• Seed
• $1.0M – $3.0M
• New York, NY
• 63 portfolio companies

PrimeAging Fund invests in startups innovating around aging-in-place, caregiving, and solutions improving elder independence.

• Healthcare
• Other

• Seed, Pre-Seed
• $250K – $1.5M
• San Diego, CA
• 1 portfolio company

Life science venture fund focused on early-stage investments in life science tools, molecular diagnostics and innovative therapeutics, with emphasis on genomics, proteomics and next-gen analytical equ...

• Other
• Consumer
• Real Estate

• Series A, Series B, early-growth
• Palo Alto, California
• 8 portfolio companies

Early-stage firm dedicated to investing in products, services, and technologies for the aging population.

• Other

• Seed
• $250K – $1.0M
• New York, NY
• 1 portfolio company

Primitive Ventures is focused on backing the most promising blockchain and crypto-related startups worldwide.

• Other
• AI / ML
• Developer Tools

• Seed
• $1.0M – $5.0M
• San Francisco, CA
• 25 portfolio companies

Backs transformative platforms leveraging AI and blockchain for financial markets and capital efficiency.

• AI / ML
• Other
• Developer Tools

• Pre-Seed, Seed
• $500K – $5.0M
• New York, NY
• 15 portfolio companies

Invests in early-stage startups addressing climate change with scalable solutions in energy, finance, and infrastructure.

• Climate / Energy
• Other

• Seed, Series A
• $500K – $3.0M
• Princeton, NJ
• 2 portfolio companies

Specialized in breakthrough materials for electronics, fabrication processes, and high-performance industrial applications.

• Other
• SaaS

• Pre-Seed, Seed
• $250K – $7.5M
• Austin, TX
• 2 portfolio companies

Prism focuses on early-stage founders creating interactive discovery and buying experiences online, making shopping more experiential using emerging technologies.

• Other
• SaaS

• Pre-Seed, Seed
• $250K – $2.0M
• San Francisco, CA
• 14 portfolio companies

Pre-seed fund backing technical founding teams building ambitious software/tech companies at formation.

• SaaS
• Other

• Pre-Seed, Seed
• $250K – $1.0M
• San Francisco, CA
• 2 portfolio companies