Venture Capital Firms in San Francisco

Browse 1,278 venture capital firms headquartered in San Francisco. Median check across the 1250 firms that disclose a range is $500K–$2.5M; most active at Seed, Pre-Seed, Series A; concentrated in SaaS, AI / ML, Enterprise. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified San Francisco VC firms

Socially Invested

Dedicated to building the next generation of social networks designed for authentic user engagement and platform equity.

  • Other
  • Pre-Seed, Seed
  • $250K – $750K
  • San Francisco, CA
  • 2 portfolio companies

Sofinnova Partners

Sofinnova invests in early-stage companies in therapeutic innovation, particularly biotech and immuno-oncology.

  • Healthcare
  • Other
  • Seed, Series A
  • $500K – $15.0M
  • Paris, France (US office: San Francisco, CA)
  • 141 portfolio companies

SoftBank Vision Fund

SoftBank likes backing bold startups aiming to redefine consumer ecosystems with global scale potential.

  • Consumer
  • Fintech
  • Seed, Growth
  • $1.0M – $50.0M
  • San Francisco, CA
  • 2 portfolio companies

SoftTech VC

Focused on pre-seed and seed investments in software startups, primarily in B2B SaaS models.

  • Other
  • SaaS
  • Pre-Seed, Seed
  • $250K – $1.0M
  • San Francisco, CA
  • 2 portfolio companies

Solo Capital Partners

An emerging solo GP fund targeting disruptive fintech and healthtech innovations at the seed stage.

  • Fintech
  • Healthcare
  • Pre-Seed, Seed
  • $1.0M – $3.0M
  • San Francisco, CA
  • 2 portfolio companies

Soma AI Capital

Focuses exclusively on AI-driven startups and data infrastructure companies leveraging predictive analytics or data layering strategies.

  • AI / ML
  • Developer Tools
  • SaaS
  • Pre-Seed, Seed
  • $100K – $500K
  • San Francisco, CA
  • 2 portfolio companies

Soma Capital

Pre-seed/seed investor backing technical founders, often first institutional check in software and AI.

  • Other
  • Enterprise
  • AI / ML
  • Pre-Seed, Seed
  • $100K – $1.0M
  • San Francisco, CA
  • 2 portfolio companies

Soma Capital

Soma backs software-driven startups across crypto, fintech, and marketplace categories, often at early growth stages. The firm is comfortable with globally oriented infrastructure businesses and produ...

  • SaaS
  • Marketplace
  • Other
  • Pre-Seed, Seed, Series A
  • $250K – $1.0M
  • San Francisco, CA
  • 13 portfolio companies

Soma Capital Health

Focused on bringing transformative AI-enabled SaaS and payments innovation to healthcare ecosystems, especially in outpatient and clinical workflows.

  • Other
  • SaaS
  • Pre-Seed, Seed
  • $500K – $2.0M
  • San Francisco, CA
  • 1 portfolio company

Sonder Ventures

Invests in transformative travel tech and AI-driven consumer platforms enabling discovery and personalization.

  • Other
  • AI / ML
  • Pre-Seed, Seed
  • $500K – $3.0M
  • San Francisco, CA
  • 2 portfolio companies

SoundWaves Ventures

Invests in pioneering technologies at the intersection of voice AI and productivity, aiming to enhance human-computer interaction.

  • Other
  • Pre-Seed, Seed
  • $250K – $3.0M
  • San Francisco, CA

South Park Commons

South Park Commons backs ambitious founders building at the frontier, actively seeking technical risk and investing as early as pre-idea, pre-product, or pre-traction. It also invests at Seed+ and sup...

  • Other
  • AI / ML
  • Enterprise
  • Pre-Seed
  • $1.0M – $10.0M
  • San Francisco, California, United States
  • 12 portfolio companies

Spark Capital

We believe in the founders who build the future.

  • Consumer
  • Enterprise
  • Fintech
  • Seed, Series A
  • $1.0M – $20.0M
  • US-SF
  • 30 portfolio companies

Spark Learning Ventures

Aims to back innovative startups enhancing educational outcomes using adaptive technologies and interactive content.

  • Other
  • EdTech
  • Healthcare
  • Seed, Pre-Seed
  • $500K – $2.0M
  • San Francisco, CA
  • 7 portfolio companies

SparkPlug Ventures

SparkPlug Ventures focuses on helping early-stage direct-to-consumer hardware companies scale their e-commerce platforms and efficiently reach a target audience.

  • Other
  • Consumer
  • Pre-Seed
  • $100K – $2.0M
  • San Francisco, CA
  • 2 portfolio companies

SpatialVentures

SpatialVentures focuses on early-stage investments in industrial design innovation and AI-driven CAD solutions.

  • Other
  • AI / ML
  • Pre-Seed
  • $750K – $2.0M
  • San Francisco, CA
  • 1 portfolio company

Specialist Startup Fund

Focuses exclusively on AI-driven solutions disrupting traditional SMB workflows.

  • AI / ML
  • Other
  • Pre-Seed, Seed
  • $250K – $600K
  • San Francisco, CA

Specific Ventures

Specific Ventures focuses exclusively on early-stage startups innovating in HealthTech, Digital Health, and mental wellness with scalable SaaS models.

  • Healthcare
  • Other
  • Seed
  • $250K – $1.5M
  • San Francisco, CA
  • 2 portfolio companies

Spectrum Equity Angels

An angel network focusing on empowering LGBTQ+ founders and startups transforming community and social inclusion.

  • Other
  • Pre-Seed
  • $500K – $3.0M
  • San Francisco, CA
  • 2 portfolio companies

Spectrum Innovate

Focused on disruptive B2B SaaS and ERP technologies that enhance business operations for the SMB sector.

  • SaaS
  • Other
  • Healthcare
  • Pre-Seed, Seed
  • $300K – $1.0M
  • San Francisco, CA
  • 7 portfolio companies

Spider Capital

Spider Capital is a seed-stage venture firm that invests in applied AI software companies disrupting physical or “old economy” industries, focusing primarily on the U.S. and Canada with select investm...

  • AI / ML
  • Other
  • Pre-Seed, Seed
  • $100K – $5.0M
  • San Francisco, California, United States
  • 17 portfolio companies

Spoon Ventures

Focused on the intersection of technology and food innovation, including smart consumer hardware.

  • Food / AgTech
  • Other
  • Pre-Seed, Seed
  • $500K – $3.0M
  • San Francisco, CA
  • 2 portfolio companies

Sporting Tech Ventures

Invests in early-stage SportsTech and fintech innovations aimed at enhancing athletic program management and financial compliance.

  • Other
  • Fintech
  • SaaS
  • Seed
  • $1.0M – $3.0M
  • San Francisco, CA

SportsTech Ventures

Focused on investing in emerging sports technologies with a spotlight on SaaS and e-commerce models focused on athletic performance.

  • Other
  • SaaS
  • Seed, Early
  • $1.0M – $10.0M
  • San Francisco, CA

Showing 1057–1080 of 1278 firms — page 45 of 54.

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