Venture Capital Firms in Chicago

Browse 717 venture capital firms headquartered in Chicago. Median check across the 708 firms that disclose a range is $500K–$2.5M; most active at Seed, Pre-Seed, Series A; concentrated in SaaS, AI / ML, Enterprise. Every firm is verified — explore their thesis, check size, and portfolio, then get matched with the best-fit investors for your startup.

Verified Chicago VC firms

SalesTech Capital

Specializes in B2B SaaS companies that are innovating in sales technology and process improvement.

  • Other
  • SaaS
  • Pre-Seed
  • $50K – $250K
  • Chicago, IL

Sandbox Capital

Backs early-stage startups building infrastructure for entrepreneurs, with a focus on SaaS and marketplace models.

  • Marketplace
  • Other
  • SaaS
  • Pre-Seed
  • $300K – $2.5M
  • Chicago, IL
  • 1 portfolio company

Sassafras Capital

Targets enterprise software solutions with a strong AI component, focusing on innovations that drive enterprise productivity and efficiency.

  • Enterprise
  • AI / ML
  • Seed
  • $1.5M – $4.0M
  • Chicago, IL
  • 1 portfolio company

ScaleUp Health

Focuses on startups driving innovations in preventive health and wellness, leveraging AI for better client management.

  • Healthcare
  • AI / ML
  • Pre-Seed, Seed
  • $100K – $2.5M
  • Chicago, IL

ScaleWell Partners

Invests in early-stage SaaS businesses solving organizational challenges, with a focus on scaling talent and productivity.

  • SaaS
  • Other
  • Seed
  • $750K – $5.0M
  • Chicago, IL
  • 2 portfolio companies

SchoolTech Capital

Investing in technology solutions that advance educational administration and student experiences within school systems.

  • EdTech
  • SaaS
  • Pre-Seed, Seed
  • $750K – $3.0M
  • Chicago, IL

ScopeAI Ventures

Investing in AI startups revolutionizing human resources, corporate training, and enterprise productivity.

  • AI / ML
  • Other
  • SaaS
  • Pre-Seed, Seed
  • $250K – $2.0M
  • Chicago, IL
  • 3 portfolio companies

Second Century Ventures (NAR Ventures)

Strategic venture arm affiliated with the National Association of REALTORS®, investing in technology impacting agents, brokerages, and transactions.

  • Other
  • SaaS
  • Seed, Series A
  • $250K – $2.0M
  • Chicago, IL
  • 3 portfolio companies

SectorShift Capital

SectorShift Capital bets on niche AI technologies that enhance operational efficiencies in field services and skilled trades.

  • Other
  • Seed
  • $500K – $3.0M
  • Chicago, IL
  • 1 portfolio company

Secure Horizon Ventures

Dedicated to investing in cybersecurity solutions that offer robust protection layers for enterprises.

  • Security
  • Seed
  • $1.0M – $3.0M
  • Chicago, IL
  • 1 portfolio company

SecuriStart Fund

Dedicated to supporting early-stage cybersecurity startups with unique product offerings.

  • Security
  • Seed
  • $500K – $2.5M
  • Chicago, IL
  • 1 portfolio company

Seed Data Labs

Invests in innovative data infrastructure and software solutions designed to optimize enterprise data workflows.

  • Developer Tools
  • Enterprise
  • Seed
  • $400K – $1.0M
  • Chicago, IL
  • 1 portfolio company

Seismic Capital

Invests in marketplaces and SaaS platforms leveraging blockchain technologies to optimize workflows and marketplaces.

  • Marketplace
  • Other
  • SaaS
  • Seed, Series A
  • $500K – $3.0M
  • Chicago, IL
  • 11 portfolio companies

Sensor Ventures

Focuses on IoT and telematics innovations that transform logistics operations with hardware-software integration.

  • Other
  • Deep Tech
  • Seed, Series A
  • $300K – $5.0M
  • Chicago, IL
  • 2 portfolio companies

Sentry AI Fund

Backing innovative startups in AI-enabled security systems for enterprise applications.

  • Security
  • AI / ML
  • Pre-Seed
  • $200K – $1.0M
  • Chicago, IL

Serial Metric Ventures

Serial Metric Ventures focuses exclusively on early-stage investments in industrial automation, CAD software, and AI-driven engineering tools.

  • Other
  • SaaS
  • AI / ML
  • Pre-Seed, Seed
  • $500K – $3.0M
  • Chicago, IL

ServTech Capital

Focuses exclusively on innovative technologies that enhance operations in field services and small businesses.

  • Other
  • Pre-Seed, Seed
  • $200K – $750K
  • Chicago, IL

ServiceCrafters Capital

Dedicated to B2B SaaS platforms revamping the service industry with technology-driven frameworks.

  • SaaS
  • Other
  • Seed, Series A
  • $750K – $5.0M
  • Chicago, IL
  • 1 portfolio company

Shift Venture Partners

Invests in HR Tech and B2B SaaS innovations that enhance operational efficiencies for shift-based workforces.

  • Other
  • SaaS
  • Enterprise
  • Pre-Seed, Seed
  • $1.0M – $3.5M
  • Chicago, IL
  • 74 portfolio companies

Signal Alpha Ventures

Focused on platforms leveraging AI to streamline B2B workflows, especially in sales and customer operations.

  • Other
  • Seed, Series A
  • $500K – $3.0M
  • Chicago, IL
  • 2 portfolio companies

Signal Catalyst Fund

Sector-focused fund investing in wireless, RF innovations, and next-generation chip-building infrastructure.

  • Other
  • Developer Tools
  • AI / ML
  • Pre-Seed
  • $300K – $6.0M
  • Chicago, IL
  • 33 portfolio companies

Signal Hill Ventures

Focused on data-driven startups modernizing workflows in the B2B space, including analytics, sales strategies, and enterprise enablement tools.

  • SaaS
  • Other
  • Enterprise
  • Seed
  • $250K – $2.5M
  • Chicago, IL
  • 25 portfolio companies

Signal Media Ventures

Invests exclusively in the next wave of digital media platforms and technologies.

  • Other
  • Seed
  • $500K – $2.5M
  • Chicago, IL
  • 1 portfolio company

SignalDrive Ventures

Focused on AI software that provides actionable insights and enhanced decision-making processes for enterprise.

  • Other
  • SaaS
  • AI / ML
  • Seed
  • $2.0M – $5.0M
  • Chicago, IL
  • 1 portfolio company

Showing 577–600 of 717 firms — page 25 of 30.

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