Venture Capital Firms in Boston

Seed-stage venture firm with exposure to real estate software and data-driven workflow tools. Suitable for B2B products that operationalize brokerage and transactions.

• Real Estate
• SaaS
• Consumer

• Seed
• Boston, Massachusetts
• 42 portfolio companies

Focused exclusively on early-stage HealthTech solutions that streamline hospital operations, improve patient outcomes, or optimize payer reimbursement.

• Healthcare
• SaaS
• Other

• Seed, Pre-Seed
• $250K – $2.0M
• Boston, MA
• 26 portfolio companies

Omega Funds focuses on transformative advances across the life sciences, backing innovators in drug discovery and biotech tools.

• Other
• Healthcare

• Pre-Seed, Seed, Series A
• $250K – $2.0M
• Boston, MA
• 2 portfolio companies

Invests in cutting-edge biotech innovations and AI applications revolutionizing healthcare delivery.

• Healthcare
• Other

• seed+, Series A
• $2.0M – $8.0M
• Boston, MA
• 2 portfolio companies

Invests in immigrant founders building scalable B2B and technical infrastructure solutions using AI.

• Other
• SaaS
• Developer Tools

• Pre-Seed, Seed
• $250K – $2.0M
• Boston, MA
• 53 portfolio companies

B2B SaaS specialist known for PLG; primarily later than pre-seed but does seed selectively.

• Other
• SaaS

• Seed
• $500K – $2.0M
• Boston, MA
• 3 portfolio companies

Invests in B2B platforms that revolutionize mid-market operations and enhance e-commerce efficiencies.

• SaaS
• Other

• Seed
• $1.0M – $4.0M
• Boston, MA
• 1 portfolio company

Focuses on startups leveraging IoT and AI to transform operational systems in manufacturing and energy.

• Other
• AI / ML

• Seed
• $750K – $2.5M
• Boston, MA
• 1 portfolio company

Dedicated to enhancing AI infrastructure capabilities and investing in companies transforming machine learning efficiencies.

• AI / ML
• Developer Tools

• Pre-Seed, Seed
• $500K – $3.0M
• Boston, MA
• 5 portfolio companies

Optum Ventures invests from seed through growth in companies at the intersection of healthcare and technology, including value-based care delivery, enterprise software and enabling infrastructure, and...

• Healthcare
• AI / ML

• Seed, Series A
• $1.5M – $5.0M
• Boston, Massachusetts, United States
• 1 portfolio company

Focused on pre-seed and seed investments in enterprise-scale data and developer infrastructure for hybrid/multi-cloud ecosystems.

• Developer Tools
• Other
• SaaS

• Pre-Seed, Seed
• $250K – $2.0M
• Boston, MA
• 1 portfolio company

Early-stage fund backing next-gen software solutions for foodservice and SMB retailers.

• Other
• SaaS

• Pre-Seed, Seed
• $200K – $1.5M
• Boston, MA
• 3 portfolio companies

Focuses on early-stage companies offering productivity and compliance automation tools that streamline regulated workflows.

• Other

• Pre-Seed, Seed
• $100K – $2.0M
• Cambridge, MA
• 2 portfolio companies

Focus on AI and next-gen software transforming healthcare workflows, including clinical decision support.

• Healthcare
• Other

• Seed, Series A
• $500K – $3.0M
• Boston, MA
• 2 portfolio companies

PathAI Ventures invests in early-stage companies developing AI technologies for pathology and diagnostics.

• Healthcare
• Other
• AI / ML

• Seed
• $250K – $3.0M
• Boston, MA

Dedicated to early-stage biotech with cutting-edge innovations in oncology and cell therapy solutions, focusing on niche applications.

• Healthcare
• Other

• Pre-Seed, Seed
• $250K – $3.0M
• Cambridge, MA
• 16 portfolio companies

Focused on transforming education through innovative SaaS solutions, with a strong emphasis on operational improvements.

• EdTech
• SaaS

• Pre-Seed
• Up to $2.0M
• Boston, MA

Investing in innovative pediatric solutions that offer unique technology to improve child healthcare and developmental outcomes.

• Other
• Healthcare
• EdTech

• Seed
• $500K – $2.0M
• Boston, MA
• 1 portfolio company

Percolate Ventures focuses on innovative startups creating new paradigms in FoodTech and marketplaces that foster unique consumer experiences.

• Food / AgTech
• Marketplace
• Consumer

• Pre-Seed, Seed
• $250K – $750K
• Boston, MA
• 5 portfolio companies

Perennial Edge Ventures invests in transformative early-stage startups building enterprise SaaS platforms and cloud management tools.

• Other
• SaaS

• Pre-Seed, Seed
• $1.0M – $5.0M
• Boston, MA
• 1 portfolio company

Invests in companies building critical decision-making and control systems for regulated and high-consequence industries, especially healthcare and industrial domains.

• Enterprise
• Other
• Healthcare

• Series A
• $2.5M – $15.0M
• Boston, MA
• 3 portfolio companies

Invests in startups revolutionizing pet ownership and care through marketplaces, platforms, and engaging digital tools.

• Other
• Marketplace
• Consumer

• Seed
• $250K – $1.5M
• Boston, MA
• 2 portfolio companies

Supports biotech and life sciences startups building transformational companies that solve big, meaningful problems.

• Healthcare
• Other

• Pre-Seed, Seed
• $500K – $5.0M
• Cambridge, MA
• 2 portfolio companies

Backing science-first startups solving problems in synthetic biology, biotech, and health innovation areas.

• Healthcare
• Other

• Pre-Seed, Seed
• $100K – $2.0M
• Boston, MA
• 11 portfolio companies