Series A SaaS Venture Capital Firms

Growth-oriented early-stage investor with a venture practice that backs enterprise software and select industrial technology companies.

• Enterprise
• Other
• SaaS

• Pre-Seed, Seed, Series A
• $500K – $3.0M
• Arlington, Virginia
• 19 portfolio companies

Enterprise software specialist with an early-stage practice (Sapphire Sport) investing in seed/early rounds.

• Enterprise
• SaaS
• Other

• Seed, Series A
• $1.0M – $3.0M
• Palo Alto, CA
• 6 portfolio companies

Global technology investment firm focused on enterprise software.

• Enterprise
• Healthcare
• Fintech

• Series A, Series B, Growth
• $5.0M – $50.0M
• US-SF
• 66 portfolio companies

ScOp backs technical B2B software and deep-tech startups, with recent visibility in AI semiconductor design and verification through ChipAgents. The firm is a strong fit for pre-seed infrastructure so...

• AI / ML
• Other
• SaaS

• Pre-Seed, Seed, Series A
• $250K – $2.0M
• Santa Barbara, California
• 40 portfolio companies

Backing B2B solutions that optimize supply chains through AI and SaaS innovations.

• AI / ML
• Other
• SaaS

• Seed, Series A
• $300K – $2.0M
• London, UK

Partner with category-defining enterprise software companies.

• Enterprise
• SaaS
• Developer Tools

• Series A, Series B
• $5.0M – $40.0M
• US-SF
• 29 portfolio companies

Focuses on infrastructure stack startups enhancing speed, scalability, and efficiency for enterprise clients globally.

• Other
• SaaS

• Seed, Series A
• $300K – $2.0M
• Tel Aviv, Israel
• 1 portfolio company

ScaleHealth Ventures invests in companies developing cutting-edge solutions in HealthTech, with a strong interest in scalable B2B SaaS models.

• Healthcare
• SaaS
• Enterprise

• Seed, Series A
• $1.0M – $3.0M
• Los Angeles, CA
• 23 portfolio companies

Strategic venture arm affiliated with the National Association of REALTORS®, investing in technology impacting agents, brokerages, and transactions.

• Other
• SaaS

• Seed, Series A
• $250K – $2.0M
• Chicago, IL
• 3 portfolio companies

Focused on investing in AI-powered companies solving foundational business and marketing challenges.

• AI / ML
• SaaS

• Seed, Series A
• $2.0M – $5.0M
• San Diego, CA
• 2 portfolio companies

Dedicated to investing in innovative enterprise software solutions enhancing the digital transformation of Asia-Pacific businesses.

• Enterprise
• SaaS

• Seed, Series A
• $1.0M – $5.0M
• Singapore
• 2 portfolio companies

Invests in marketplaces and SaaS platforms leveraging blockchain technologies to optimize workflows and marketplaces.

• Marketplace
• Other
• SaaS

• Seed, Series A
• $500K – $3.0M
• Chicago, IL
• 11 portfolio companies

Invests in early-stage technology startups across high-growth sectors, using curated portfolios and co-investment. The firm does not publish a verifiable current range for typical initial check sizes.

• Enterprise
• SaaS
• AI / ML

• Seed+, Series A
• $500K – $3.0M
• Milton, Georgia, United States
• 100 portfolio companies

Serena Ventures backs bold founders reshaping how we live, work, move, and connect, with a purpose to expand access, ownership, and opportunity at scale — especially supporting underrepresented founde...

• SaaS
• Developer Tools
• AI / ML

• Seed, Series A
• $100K – $500K
• San Francisco, California, United States
• 5 portfolio companies

Seed and Series A investor with broad software and AI interest. Strong option for AI-driven SaaS with diverse founder profiles and market potential.

• AI / ML
• SaaS
• Other

• Seed, Series A
• $500K – $5.0M
• Los Angeles, California

Dedicated to B2B SaaS platforms revamping the service industry with technology-driven frameworks.

• SaaS
• Other

• Seed, Series A
• $750K – $5.0M
• Chicago, IL
• 1 portfolio company

Strategic venture arm investing in enterprise software that advances digital workflows, IT, security, and automation.

• Enterprise
• Other
• SaaS

• Seed, Series A
• $500K – $5.0M
• Santa Clara, CA
• 3 portfolio companies

Early-stage venture firm investing in bold entrepreneurs.

• Enterprise
• Consumer
• Fintech

• Seed, Series A
• $500K – $10.0M
• US-SF
• 7 portfolio companies

Specialized in scaling digital platforms transforming healthcare, marketplaces, or SaaS applications in B2B industries.

• Marketplace
• Healthcare
• SaaS

• Seed, Series A
• $750K – $3.0M
• Austin, TX
• 3 portfolio companies

• SaaS
• Other
• Consumer

• Seed, Series A
• $50K – $100K

Strategic investor in commerce infrastructure and e-commerce enablement, with relevance to fulfillment and delivery adjacency.

• Other
• SaaS
• Enterprise

• Seed, Series A
• $250K – $1.0M
• Ottawa, Ontario
• 7 portfolio companies

Focused on early-stage tech startups at the intersection of media, advertising innovation, and scalable SaaS solutions.

• Other
• SaaS

• Series A
• $1.0M – $4.0M
• Austin, TX
• 2 portfolio companies

Corporate venture arm focused on industrial automation, factory tech, IoT, and software adjacent to Siemens’ industrial ecosystem. Strong fit for companies integrating with plant systems and industria...

• Other
• Deep Tech
• Healthcare

• Seed, Series A
• $2.0M – $20.0M
• Munich, Bavaria
• 8 portfolio companies

Sift Ventures specializes in backing next-generation marketplaces and SaaS-driven platforms disrupting legacy industries.

• Marketplace
• SaaS
• Consumer

• Pre-Seed, Seed, Series A
• $500K – $5.0M
• San Francisco, CA
• 2 portfolio companies