Seed Venture Capital Firms

Helix Microfund targets disruptive biotech startups focusing on biomaterials and tissue engineering.

• Healthcare
• Other

• Pre-Seed, Seed
• $100K – $200K
• London, UK
• 6 portfolio companies

Helix VC invests in blockchain-enabled cross-border payment platforms and fintech startups working at the intersection of crypto and traditional financial systems.

• Other
• Fintech

• Pre-Seed, Seed
• $150K – $1.0M
• San Francisco, CA
• 2 portfolio companies

Specializes in early-stage synthetic biology startups revolutionizing food systems, ingredients, and industrial applications.

• Healthcare
• Other
• Food / AgTech

• Pre-Seed, Seed
• $500K – $4.0M
• San Francisco, CA
• 2 portfolio companies

B2B SaaS-focused micro VC actively backing early-stage marketplace startups that streamline industry-specific workflows.

• SaaS
• Marketplace
• Consumer

• Pre-Seed, Seed
• $500K – $2.0M
• Austin, TX
• 2 portfolio companies

Focused on technologies that improve cannabis cultivation processes, from automation to yield optimization in indoor and greenhouse setups.

• Other
• Food / AgTech

• Pre-Seed, Seed
• $100K – $1.0M
• Denver, CO
• 2 portfolio companies

Focuses on consumer and AI-powered startups that foster human connection.

• Other
• AI / ML
• Consumer

• Pre-Seed, Seed
• $500K – $5.0M
• London, UK
• 2 portfolio companies

Investing in innovative HealthTech solutions that prioritize women's health and privacy.

• Healthcare
• Other

• Pre-Seed, Seed
• $50K – $250K
• Austin, TX
• 22 portfolio companies

Her Impact Ventures is dedicated to investing in innovative health solutions for women, focusing on technologies that elevate women's wellness.

• Other
• Healthcare

• Pre-Seed, Seed
• $100K – $500K
• Boston, MA
• 1 portfolio company

Primarily invests in women-founded businesses in Southeast Asia. Focus is on financial access, education, and inclusion.

• Fintech
• Other
• EdTech

• Pre-Seed, Seed
• $100K – $1.0M
• Singapore
• 2 portfolio companies

Investing in women-led and women-focused startups, particularly innovations that address maternal and digital health.

• Healthcare
• Other
• AI / ML

• Pre-Seed, Seed
• $50K – $250K
• San Diego, CA
• 2 portfolio companies

Focused exclusively on enabling early-stage, lean AI startups through targeted investments in SaaS-based enterprise solutions.

• Other
• Enterprise
• AI / ML

• Pre-Seed, Seed
• $250K – $1.0M
• Atlanta, GA
• 1 portfolio company

Hercules backs companies involved in public-private partnerships and financial innovations for government and enterprise.

• Other
• Fintech
• Enterprise

• Seed, Pre-Seed, Growth
• $1.0M – $5.0M
• Palo Alto, CA
• 31 portfolio companies

Investing in platforms that trace and enhance cultural roots through digital experiences.

• EdTech
• Marketplace
• Other

• Pre-Seed, Seed
• $250K – $1.5M
• San Francisco, CA
• 1 portfolio company

Focuses on technology that revolutionizes interactive entertainment, particularly AR/VR, gaming, and AI-powered platforms.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $1.0M
• Los Angeles, CA
• 1 portfolio company

Seed-focused emerging manager from Israel investing in deep technical enterprise software, including cybersecurity and cloud infrastructure.

• Security
• Developer Tools
• Other

• Pre-Seed, Seed
• $500K – $1.5M
• Tel Aviv, Israel
• 17 portfolio companies

Hexagon Security Partners is a micro-fund dedicated to Cybersecurity, supporting promising Seed-stage companies with scalable solutions.

• Security

• Seed
• $500K – $2.0M
• Austin, TX
• 1 portfolio company

A fund focused on the future of creative work, backing startups that help creators build, earn, and flourish. It invested across tools, services, commerce, payments, and software for creators and adja...

• Other
• Marketplace

• Pre-Seed, Seed
• US
• 1 portfolio company

Focused on early-stage AI and SaaS startups that enhance productivity and workflows for businesses.

• Other
• SaaS
• Enterprise

• Pre-Seed, Seed
• $250K – $2.0M
• Austin, TX
• 1 portfolio company

High Alpha creates and funds B2B SaaS companies, with its capital investment arm focused on enterprise software. It also co-creates companies with founders through its venture studio.

• SaaS
• Enterprise
• Other

• Seed, Series A
• $1.0M – $5.0M
• Indianapolis, United States
• 95 portfolio companies

Regional Rocky Mountain focused specialist fund prioritizing early-stage business software architectures.

• SaaS
• Other

• Seed
• $500K – $1.5M
• Boulder, CO
• 1 portfolio company

Invests in high-performance Web3 and decentralized application (dApp) infrastructure including blockchain technology for DeFi and gaming ecosystems.

• Other
• AI / ML
• Developer Tools

• Seed, Series A
• $500K – $5.0M
• Tel Aviv, Israel
• 2 portfolio companies

High Voltage Capital invests in early-stage startups in Europe and North America working on clean energy, grid technology, and fusion systems.

• Climate / Energy
• Other
• SaaS

• Seed, Pre-Seed
• $300K – $3.0M
• Berlin, Germany
• 2 portfolio companies

Focused on creating and launching enterprise software companies from scratch, particularly in the B2B SaaS space.

• SaaS
• Enterprise

• Pre-Seed, Seed
• $250K – $1.0M
• Indianapolis, IN
• 92 portfolio companies

HighConviction Ventures backs founders creating user-friendly blockchain and crypto tools aimed at driving mass adoption of financial decentralization.

• Other
• AI / ML

• Pre-Seed, Seed
• $250K – $1.0M
• Denver, CO
• 1 portfolio company